Patents Represented by Attorney, Agent or Law Firm Joanne Giesser
  • DNA molecules encoding splice variants of the human melanocortin 1 receptor protein
    Patent number: 6693184
    Abstract: The present invention relates to DNA molecules encoding splice variants of the melanocortin-1 receptor (MC-R1) protein belonging to the rhodopsin sub-family of G-protein coupled receptors, recombinant vectors comprising DNA molecules encoding MC-R1B protein, recombinant host cells which contain a recombinant vector encoding MC-R1B, the human MC-R1B protein encoded by the DNA molecule, and methods of identifying selective agonists and antagonists of MC-R1B proteins disclosed throughout this specification.
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: February 17, 2004
    Assignee: Merck & Co., Inc.
    Inventors: Andrew D. Howard, Douglas J. MacNeil, Leonardus H. T. Van Der Ploeg
  • 17 urea, thiourea, thiocarbamyl and carbamyl4-azasteroid 5-reductase inhibitors useful in the prevention and treatment of hyperandrogenic disorders
    Patent number: 5620986
    Abstract: Novel substituted 4-azasteroid 5-.alpha.-reductase inhibitors of formula (I), wherein A is (a), (b) or (c), are claimed as well as pharmaceutically acceptable salts and formulations thereof. These compounds are effective inhibitors of testosterone 5.alpha.-reductase(s) and are thus useful in the treatment of a number of hyperandrogenic conditions including benign prostatic hypertrophy, acne, seborrhea, female hirsutism, and male and female pattern baldness (alopecia).
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: April 15, 1997
    Assignee: Merck & Co., Inc.
    Inventors: Bruce E. Witzel, Richard L. Tolman
  • Pharmaceutical tablet
    Patent number: D400672
    Type: Grant
    Filed: March 21, 1996
    Date of Patent: November 3, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Kenneth A. Kramer, Ashok V. Katdare