Abstract: Vaccine formulations for inducing protective immune response to Hantaviruses in humans are disclosed. These formulations include an attenuated vaccinia virus vector containing cDNA's encoding Hantavirus nucleocapsid N protein, G1 and G2 glycoproteins. Methods for the use of these formulations also are disclosed.

Abstract: Creams formed from about 35% to about 50% fine particulates of certain poly(tetrafluoroethylene) (PTFE) resins dispersed in perfluorinated polyether oils having viscosities from about 20 cSt to about 350 cSt afford good protection against chemical warfare agents such as sulfur mustard (HD), lewisite (L), sulfur mustard/Lewisite mixtures (HL), pinacolyl methylphosphonofluoridate (soman or GD), thickened soman (TGD) and O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (vx).

Abstract: Apparatus and methods for dispensing medicinals encapsulated in a biodegrble polymer in surgical and other wounds are described. The apparatus, a microcapsule drug applicator, allows the caregiver to implant or spread measured and uniform quantities of microencapsulated medicinals in or on surgical or traumatic wounds to prevent and/or treat infections. Specific examples where microencapsulated antibiotics may prove useful include, soft-tissue wounds, following debridement and reduction or fixation of open fractures, to osteomyelitic bone after surgical debridement, after surgical insertion of prostheses such as hip/knee replacements (arthroplasty), and following vascular surgery or grafting.

Abstract: A pump and a method for pumping liquid or fluid through a pair resilient es includes a shuttle block which partially compresses the tubes in a balanced, alternating manner. The resilient tubes are held in a parallel relationship with a predetermined space defined therebetween. Within the predetermined space, a shuttle block is oscillated along the linear axis to partially compress the tubes in an alternating fashion. As one of the two parallel tubes is compressed, fluid is pumped out of the tube and at the same time fluid is drawn into the second tube as the latter tube resumes its original shape. The resilience of both tubes also is used to assist the pumping action in a balanced fashion, thereby providing a pump that has low power consumption and is lightweight.

Abstract: This invention relates to the prevention and treatment of thrombi using pminogen activators, including t-PA, urokinases, and streptokinases, in conjunction with intermittent (pulsed mode) ultrasound. A preferred modality interposes liquid-containing interface between the skin of the patient and the transducer of the ultrasound generator.

Abstract: The present invention relates to a surgical table capable of supporting a litary litter. The table, comprising a base and at least one cross member, is made of lightweight, durable material, is portable, and is relatively easy to assemble, disassemble, and package for transport. The cross member may be positioned such that the patient's head or feet are elevated or lowered relative to the table's base. The fabric of the litter is used as the direct support for the patient while the patient receives medical attention.

Abstract: Tissue adhesive compositions are disclosed which comprise at least one 2-noacrylate ester of the general formula (I) ##STR1## in admixture with from about 2 percent to about 25 percent of at least one oxalic acid polymer of the general formula (II) ##STR2##

Abstract: The compounds belong to the class of non-narcotic, non-opiate derivatives the 1-phenylalkanecarboxylic acid basic structure useful as anticonvulsant and neuroprotective agents. The compounds include novel derivatives as well as previously published species. Methods for controlling convulsions in a variety of pharmaceutical formulations and modalities are also provided.

Abstract: Nucleotide sequences coding for Hantaan virus nucleocapsid protein and glproteins G1 and G2 can be used to produce these proteins for vaccine and diagnostic applications.

Abstract: A method of preparing substantially purified alkaloids from seeds, stems, uit-rind and bark of a plant selected from Picralima nitida, Gongronema latifolia, Dorstenia multiradiata, Cola attiensis, Rothmania withfieldii and Desmodium gangeticum, for use in the treatment of protozoal diseases, comprising:pulverizing said plant;a first solvent, drying the extracted material and re-extracting the dried material with a different solvent;extracting a fresh sample of said plant with boiling water;filtering and concentrating the boiling water solvent extracts under reduced pressure;concentrating the dried extract to a gum and re-extracting said gum with an aqueous acidic HCl solution;filtering the acidic extract and making it alkaline to a pH of about 9 with a concentration NaOH solution;extracting the alkaline solution with dichloromethane;concentrating organic layers of the extracted alkaline solution to dryness under reduced pressure to obtain an alkaloid fraction; andseparating the alkaloid fraction by liquid chr

Abstract: A height measurement system uses an inexpensive ultrasonic height measuring evice to provide an apparent height of a descending airborne object. To compensate for movement of the object during the ultrasonic measurement, a Doppler radar velocity measuring device determines the vertical velocity in a short measurement period. The measured vertical velocity is used to determine the vertical distance travelled during the ultrasonic measurement and to compensate therefor by converting the apparent height to a true height of the descending object. Updates of the true height may be obtained by storing the vertical velocity and retrieving the vertical velocity for multiplication by a time value to obtain an updated value of the true height.

Abstract: Novel compounds are provided which exhibit high levels of anti-parasitic activity, specifically against parasites of the genus Trypanosoma. The compounds are comprised of aryl-substituted quaternary heteroaromatic salts which include a positively charged imidazolium or other heterocyclic ring, a linking group, a phenyl ring, and a polar functional group. The polar functional group is preferably a quanylhydrazone or a heterocyclic hydrazone. A method is also provided for treating the diseases associated with Trypanosoma parasites which comprises administering to infected animals or humans an effective amount of a compound of the present invention.

Abstract: The present invention relates to a synergistic antimicrobial compound (mafenide-phosphanilate) having especially high activity for topical prophylaxis and therapy of burn wound infections. The invention further relates to anti-microbial pharmaceutical compositions and a method for treating microbial infection. More particularly, the invention relates to the effective unexpectedly improved treatment of burn wounds involving Pseudomonas and Proteus bacteria.

Abstract: A slide (19) is driven by a gear mechanism (21) to position a scanning device (15) in a radial direction relative to the record carrier between an innermost track 3) and an outermost track (4), a stop (38) of the slide (19) abutting against a fixed stop (39) on the apparatus when the scanning device (15) is positioned at the outermost track (4). The gear mechanism (21) comprises a pinion (24) driven by a motor (20) and two gear racks (26, 27) which are tensioned relative to one another by a spring (25) and driven by the pinion, one of the gear racks (27) being fixed to the slide (19). When the slide (19) abuts against the fixed stop (39) the gear rack (27) is not in mesh with the pinion (24) and at least one end tooth (40) of the other gear rack (26) is situated in a range where it can mesh with the pinion (24).

Abstract: A method and apparatus are revealed for recording information on a record carrier (1) having a magneto-optical recording layer (2), a pattern of magnetic domains (23, 24) having a first and a second direction of magnetization being formed in the recording layer (2). In accordance with the method, areas (22) of the recording layer are heated by the radiation pulses (20). The heated areas (22) are magnetized by means of a coil (12) which is energized with energizing-current pulses (21) which lag the radiation pulses (20) to such an extent that cooling of the areas (22) takes place substantially during the generation of the energizing pulses (12).

Abstract: Method of and arrangement for image data compression by vector quantization in accordance with a precoding in blocks, thereafter comparing by means of a neural network precoded blocks with reference words stored in the form of a code book so as to transmit selected indices to a receiver. In accordance with the method, the neural network effects a learning phase with prescribed prototypes, thereafter with the aid of test vectors originating from the image generates an adaptive code book which is transmitted to the receiver. This adaptation utilizes attractors, which may be induced metastable states, of the neural network, and which are submitted to an optimizing procedure. The arrangement can process images with a view to their storage. It is also possible to utilize two devices which operate alternately, one device for generating the adaptive code book and the other one to utilize it with the object of processing television pictures in real time.

Abstract: Circuitry for processing, in a television signal, a first, low-frequency synchronizing signal on which a second, high-frequency synchronizing signal is superposed, for supplying standardized television signal capable of being processed by a customary television signal processing arrangement or display device, respectively by inhibiting a shift between the picture content of the signal representing the television signal and the synchronizing signal.

Abstract: A record carrier (1) in the form of a disc-shaped carrier provided with a radiation-sensitive layer (6) having a servo track (4). The servo track produces track modulation by having a radial wobble, or lateral periodic deviation whose frequency is modulated with a position-information signal (FIG. 2). Apparatus (FIG. 8) is presented which forms the track pattern during manufacture of the record carrier (1). When an information signal (Vi) is recorded on the record carrier (1) and the recorded signal is read by recording and/or read apparatus (FIG. 4), the position-information signal (FIG. 2) is recovered by an FM demodulator device (60) from variations in the scanning beam (55) which are propduced by the track modulation. Moveover, a clock signal for the purpose of scanning-velocity control is recovered from this variation in the scanning beam. Furthermore, embodiments of the record carrier highly suitable for recording EFM-modulated signals are described.

Abstract: An optically readable record carrier for storing digitally coded information having a power spectrum with a substantially zero level at a predetermined frequency. The information is recorded on and/or reproduced from substantially parallel elongated tracks on the record carrier which have a periodic undulation at the aforesaid predetermined frequency. Such undulation generates a clock signal for synchronizing the recording and/or reproduction of the digitally encoded information on the tracks, and does not interfere with the recording or reproduction of such information. Apparatus is disclosed for forming such tracks on the record carrier.

Abstract: An apparatus for recording information on a disk-shaped record carrier body by a beam of radiation. The carrier body comprises a diffractive follow-on track which is capable of being scanned with an opto-electronic system so as to produce an electrical signal for controlling the position of the beam during recording of the information.