Abstract: A TiO.sub.2 hydrogel and method of preparation therefor is disclosed: TiO.sub.2 particles ranging in size from at least about 50 nm to about 150 nm wherein the particle is about 20% to about 90% anatase are disclosed. Topical sunscreen compositions, which comprise 1% to about 15% anatase/amorphous TiO.sub.2 are also disclosed. This composition provides UVA and UVB protection without concomitant dulling or discoloring the skin. The composition also has enhanced stability, is invisible, is easy to apply in an even manner and resists discoloration (or "color-changing") or decomposition on the shelf or on the skin.

Abstract: A make-up composition in the form of a water-in-off emulsion comprising a silicone phase, humectanct, pigment and organic amphiphilic material capable of forming smectic lyotropic liquid crystals in product or on the skin. The make-up composition exhibits superior short and longer term moisturisation and skin feel, together with improved product stability and spreadability.

Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of a therapeutically active agent incorporated into or coated on the surface of a dosage form selected from the group consisting of a spherical substrate, an elliptical substrate, a hard capsule, or a compressed tablet, with a maximum diameter of about 3 mm to about 10 mm; andb. an enteric polymer coating material;wherein the dosage form has a smooth surface free from edges or sharp curves; the elliptical substrate and the hard capsule have a ratio of the long to short diameters of no greater than about 1.

Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of a therapeutically active agent incorporated into or coated on the surface of a dosage form selected from the group consisting of a spherical substrate, an elliptical substrate, a hard capsule, or a compressed tablet, with a maximum diameter of about 3 mm to about 10 mm; andb. an enteric polymer coating material comprising at least one inner coating layer and one outer coating layer;wherein the dosage form has a smooth surface free from edges or sharp curves; the elliptical substrate and the hard capsule have a ratio of the long to short diameters of no greater than about 1.

Abstract: The present invention is for powder compositions containing high levels of talc, low levels of titanium dioxide and a sebum absorbing material wherein the composition has improved skin coverage, uniformity and duration of wear. The invention can be used in formulating numerous cosmetic powder compositions such as eye shadow, foundation, loose powder and the like.

Abstract: The subject invention relates to desquamation compositions comprising a combination of sulfhydryl compounds and zwitterionic surfactants. The subject invention further relates to methods of desquamation in mammalian skin and treating acne in mammalian skin.

Abstract: The present invention are anhydrous after shave lotions comprising a perfume, an alcohol, and a low viscosity silicone fluid. Said compositions have less stinging and burning than compositions known in the art. Furthermore, said compositions are economical and have good skin feel characteristics.

Abstract: The present invention is for powder compositions having high levels of talc and low levels of titanium dioxide wherein said compositions have improved skin coverage and uniformity. Said compositions comprise talc wherein said talc comprises a first talc having a particle size distribution wherein no more than about 45% of the particles are 10 microns or less; no more than about 70% of the particles are 15 microns or less and no more than about 75% of the particles are 20 microns or less and a second talc having a particle size distribution wherein no less than about 75% of the particles are 10 microns or less, no less than about 90% of the particles are 15 microns or less and no less than about 95% of the particles are 20 microns or less. The ratio of said first talc to said second talc is from about 1:1 to about 6:1. The invention can be used in formulating numerous cosmetic powder compositions such as eye shadow, foundation, loose powder and the like.

Abstract: The subject invention relates to desquamation compositions comprising a combination of salicylic acid and certain zwitterionic surfactants. The subject invention further relates to methods of desquamation in mammalian skin and treating acne in mammalian skin.

Abstract: The subject invention involves topical depilatory compositions, at a pH of 7 or below, comprising sulfhydryl compounds. The subject invention further relates to methods for removing vellus hair from mammalian skin comprising topical application of a composition, at a pH of 7 or below, comprising a sulfhydryl compound or a cosmetically- and/or pharmaceutically-acceptable salt thereof.

Abstract: The subject invention relates to low-aqueous gelling compositions comprising optically enriched gellants having the structure: ##STR1## wherein A and B independently represent alkyl groups such that the gellant is an asymmetric, di-chiral, di-hydroxy fatty acid that is about 90% or more in the R, R or S, S form and has from about 6 to about 30 carbon atoms.

Abstract: The present invention relates to personal care compositions, especially hair care compositions, containing non-silicone, hydrophobic graft copolymers and a hydrophobic, volatile solvent for the copolymer, the solvent being selected from branched chain hydrocarbons, silicones and combinations thereof. This invention also relates to hair conditioners and hair styling products such as rinses, leave on conditioners, and combination shampoo products useful for cleansing, styling and conditioning the hair.The graft polymers should satisfy the following three criteria:(1) the graft portion is covalently bonded to the polymeric backbone portion;(2) the molecular weight of the graft portion is at least about 500; and(3) when used in a composition, such as a personal care composition for application to the hair or skin, the polymeric backbone portion should permit the graft polymer to deposit on the intended surface, such as hair or skin.

Abstract: The present invention is for mascara compositions having improved application characteristics. Said improvement is attributed to incorporation of a setting rate agent which delays the setting of the composition long enough to provide sufficient time to distribute the mascara in semi-liquid form onto the lashes as well as contribute to lash-thickening properties while avoiding negative aesthetics.

Abstract: A dual chamber-child-resistant blister package is provided. The blisters of the package include a storage chamber and a discharge chamber. In addition, the blister includes restraint means for preventing the medicament from moving from the storage chamber to the discharge chamber until a predetermined force is applied to the blister package. The medicament may not be dispensed directly from the storage chamber, since a nonrupturable layer is located adjacent the storage chamber of the blister. The nonrupturable layer includes an opening, or a mechanism such as a score line for forming and opening) through which the medicament can pass adjacent the discharge chamber. A rupturable layer is also provided to seal the medicament within the blister. Typically, the rupturable layer is located adjacent the nonrupturable layer to seal the opening in the nonrupturable layer. The blister package may also include indicia associated with the blisters to help insure compliance with complex therapeutic regimens.

Abstract: The subject invention relates to low-aqueous gelling compositions comprising optically enriched gellants having the structure: ##STR1## wherein A and B independently represent alkyl groups such that the gellant is an asymmetric, di-chiral, di-hydroxy fatty acid that is about 90% or more in the R, R or S, S form and has from about 6 to about 30 carbon atoms.

Abstract: The present invention is for mascara compositions having improved application characteristics. The improvement is attributed to incorporation of a setting rate agent which delays the setting of the composition long enough to provide sufficient time to distribute the mascara in semi-liquid form onto the lashes as well as contribute to lash-thickening properties while avoiding negative aesthetics.

Abstract: This invention relates to polymeric liquid crystals prepared from a polysaccharide and a solvent, preferably water, which are used to deliver nutrients, perfumes, flavors, drugs and other ingredients in foods, cosmetics, household soaps, health care products e.g. bar or liquid soaps, toothpaste, shampoos, creams, and lotions and other preparations. The encapsulated active vehicle comprises:(a) from about 0.001% to about 60% of an active; and(b) from about 40% to about 99.999% of a stable polymeric liquid crystal consisting essentially of:(1) from about 10% to about 90% of a solvent; and(2) from about 10% to about 90% of a polysaccharide having a molecular weight of from about 500 to about 1,000,000.

Abstract: The present invention is for long lasting, physically stable, moisturizing lipstick compositions essentially free of water. Said lipsticks contain lipophilic materials with high levels of moisturizers distributed throughout. Said lipsticks resist separation of the moisturizing material from the body of the lipstick.

Abstract: The present invention is for a process for preparing monoacetals of hydroquinone wherein said process provides for higher yields of greater purity. Said process utilizes a two step reaction wherein a protected hydroquinone is reacted with an enol ether to form a protected intermediate. Upon hydrogenolysis of said intermediate a final product, monoacetal hydroquinone, is formed having higher degree of purity and in greater yields that the yields attributed to reactions known in the art.

Abstract: The present invention provides a useful cosmetic having high ultraviolet-screening effects (sunscreening effects), and excellent safety, and giving a natural makeup finish. This composition comprises a metal oxide flake having an average thickness of from 0.01 to 3 .mu.m, and an average size of from 1 to 100 .mu.m, and a ultraviolet absorbent-encapsulated polymer resin particle obtained by polymerization of a polymer resin monomer uniformly mixed with an ultraviolet absorbent.