Abstract: A hair curler set for heating hair curling rollers includes a case accommodating a plurality of cylindrical hair curler rollers arranged in horizontal or slightly inclined parallel alignment and positioned in a row to one or both sides of an elongated heater body containing an electric resistance heater and having its longitudinal axis disposed substantially horizontally and parallel to one side of the case. The case includes cradles for positioning each of the rollers in perpendicular coaxial alignment with a respective one of a plurality of spaced apart horizontally disposed heat transfer portions on the heater body. Each roller has a metallic bottom end shaped to cooperate with the heat transfer portion of the heater body to provide a large heat transfer contact area therebetween. The case and rollers are designed so that the rollers, when positioned in the cradles, have their bottom ends elastically urged into heat-conductive contact with the heat transfer portions of the heater body.

Abstract: A competitive enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies is disclosed. This ELISA technique is more sensitive, more specific, and more accurate than known ELISA techniques. The competitive ELISA of this invention is particularly suited to the detection of human T-cell leukemia-lymphoma virus type III (HTLV-III). Antigenic or viral fragments are bound to a solid support. The bound fragments are then incubated with a heterologous antiserum which binds to the bound fragments. Test sera is then added to the bound fragments and tested for absorbance.

Abstract: The present invention is a method of preparing tetrachlorodiamine cyclohexane platinum (IV) by reacting a diamine selected from the group consisting of 1,2-diaminocyclohexane and operable isomers thereof in the form of a dihydrohalide with alkali metal or hydrogen hexachloroplatinate. The preferred hexachloroplatinate is potassium salt and the isomers utilized from the diamine are selected from the group consisting of cis, trans (d,l), trans-l, and trans-d. The process noted is where the 1,2-diaminocyclohexane is used in about equimolar amounts with hexachloroplatinate which is subjected to heating at reflux temperature for 12-24 hours in aqueous solvent, cooled and filtered.

Abstract: A cell system is disclosed for the reproducible detection and isolation of human T-lymphotropic retroviruses (HTLV-family) with cytopathic effects (HTLV-III) from patients with the acquired immune deficiency syndrome (AIDS), pre-AIDS and in healthy carriers. One neoplastic aneuploid T-cell line derived from an adult with lymphoid leukemia, and termed HT, was susceptible to infection with HTLV-III, which is transformed and provides T-cell populations which are highly susceptible to and permissive for HTLV-III, and convenient for large scale production, isolation, and biological detection of the virus. Other operational neoplastic T-cell lines which are positive for OKT4 marker, e.g., Molt 3, CEM, Ti7.4 and HUT78, can produce HTLV-III in a large amount and retain its unlimited capability for growth.

Abstract: A process for production of improved polyethylene glycol (PEG) is disclosed. This process overcomes the toxicity that results from using the known (and impure) PEG-fusion reagent by incorporation of a purification method that removes the toxic elements always present in PEG preparations stored above 0.degree. C. in the presence of oxygen.

Abstract: A cell system is disclosed for the reproducible detection and isolation of human T-lymphotropic retroviruses (HTLV-family) with cytopathic effects (HTLV-III) from patients with the acquired immune deficiency syndrome (AIDS), pre-AIDS and in healthy carriers. One neoplastic aneuploid T-cell line derived from an adult with lymphoid leukemia, and termed HT, was susceptible to infection with the new variants of HTLV, which are transformed and providing T-cell populations which are highly susceptible and permissive from HTLV-III, and convenience for large scale production, isolation and biological detection of the virus.

Abstract: A compound of the formula ##STR1## wherein Z is hydrogen and Y is nitro, inhibits the growth of murine ductal carcinoma (MXT mammary tumors).

Abstract: Human hepatitis A virus (HAV), taken directly from human clinical specimens, can be isolated and serially passaged in primary African green monkey kidney (AGMK) cell cultures. This strain induced antibody to HAV in inoculated chimpanzees and is useful for vaccine.

Abstract: Monoclonal antibodies have been developed that bind with one or more proteins located on the surface of gametes or zygotes of malaria parasites. These antibodies are specific for antigens on mosquito midgut stages of malaria parasite and sterilize the parasites in mosquitoes otherwise capable of transmitting the disease. The monoclonal antibodies are specific for the 255, 59 and 53 kilodalton surface proteins on Plasmodium falciparum and for the 25 kilodalton surface protein on zygotes and ookinetes of Plasmodium gallinaceum.

Abstract: An improved therapeutic corset which is peculiarly adapted for the sacrum, lumbar and thoracic region of the body comprises an elongated support surface formed from material that is bendable when subjected to forces encountered thereby. Disposed on the support surface and secured thereto along its edges is a flexible cover disposed thereover to form an envelope. The envelope is provided with a duct of introducing fluid therein and retaining same, thus inflating the envelope causing the surface to bend to assume a predetermined curvature, which is preferably in the shape of a crescent. The support surface is further equipped with a fastener removably securing the free ends of same to the wearer.

Abstract: Human hepatitis A virus (HAV) can be purified by a process in which master seed lots of HM-175 strain of hepatitis A virus are prepared from triply cloned virus by terminal dilution at passage level about 20 or preferably at least 20-30. The clones tested induced minimal or no hepatitis although significant antibody response was provoked in inoculated primates. A method of preparing the triply cloned inoculum is also described.

Abstract: This invention is concerned with a new compound, useful to reduce tumors in laboratory animals, having the following structural formula: ##STR1## The compound is prepared by reacting the free base of homocysteine thiolactone with all trans retinoic acid in the presence of dicyclohexylcarbodiimide as a dehydrating agent as follows: ##STR2## The reaction is carried out in a suitable non-polar solvent. The compound may also be used to agglutinize human blood platelets.

Abstract: A simplified and efficient sound generating device consisting of a self-contained audible signaling device and a means of affording said device protection against moisture and cold temperatures, comprised of a photoelectric cell, a source of energy, a sound transducer means, and appropriate container that permits the entry of light therein. When positioned in an appropriate darkened enclosure, the device permits an immediate audible signal upon the opening of said enclosure and the introduction of light therein. Said device is particularly suited for use as an aid to behavior modification programs that are associated with the need to eliminate the habitual and compulsive over-consumption of food from the diet.

Abstract: A method of inactivating a lipid virus contained in a dry protein carrier by contacting said virus-containing protein carrier for an abbreviated period of time at from 4.degree.-40.degree. C. with a composition including a halohydrocarbon treating agent and water dissolved in said treating agent. Preferred lipid viruses are Hepatitis B virus (HBV) and non-A, non-B Hepatitis (NANBH) virus.

Abstract: A hand-held smocking apparatus consisting of a crossbar and at least two fabric covered dowels rotatably and perpendicularly attached to said crossbar is suitable for performing needlework on pre-pleated material without tangling, snagging, or crushing the material.

Abstract: The invention relates to an apparatus for roughening road surfaces, which consists of a roller which is mounted on a chassis so as to be vertically adjustable, is disposed transversely to the direction of travel, is driven by a motor and is equipped with milling cutters, wherein the milling cutters are fastened resiliently on the roller.

Abstract: The invention relates to a cutting finger for finger-bar cutters of harvesting machines with a top finger and a bottom finger stamped out from flat material and connected to one another in front of the blade gap, in which cutting finger the top finger and/or the bottom finger are deformed in the region located in front of the blade gap and are connected to one another by welding.

Abstract: There is disclosed herewith a method of producing morphinan compounds by total synthesis which incorporates utilization of N-cycloalkylcarbonyl compounds, which show certain advantages over the prior art which has been previously expressed in U.S. Pat. No. 4,368,326.

Abstract: A hair roller adapted to be heated by being positioned on a hot post of a hair setting unit, consists of a plastic, cylindrical and hollow outer body, provided with outstanding teeth on its outside surface. It is closed at its upper end and open at its lower end, its hollow portion being cylindrical in its upper part, extending to about two thirds of its length, and the remaining lower third is tapered towards the lower opening. A tubular insert, made of a resilient aluminum alloy, extends the length of the hollow portion. It is longitudinally slit over its entire length, and the two edges of the slit extend to both sides of an inwardly projecting longitudinal ridge provided in the cylindrical part of the hollow portion. The insert is provided with an outwardly projecting lug on one edge of the slit, which engages with a perforation or a recess in the outer body.