Patents Represented by Attorney Joseph J. Kenny

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  • Human cytokine polypeptide
    Patent number: 6008022
    Abstract: The invention relates to human cytokine polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: December 28, 1999
    Assignee: Human Genome Sciences, Inc.
    Inventors: Kui Su, Yi Li, Haodong Li
  • Epidermal differentiation factor
    Patent number: 5981220
    Abstract: A human epidermal differentiation factor polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for treating and/or preventing skin diseases. Diagnostic assays for detecting mutations in a nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention are also disclosed.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: November 9, 1999
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Ping Feng, Patrick J. Dillon, Reiner Gentz
  • Cytostatin I
    Patent number: 5977309
    Abstract: A human cytostatin I polypeptide an DNA encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of cancers, particularly breast cancer, leukemias, and other matastases.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: November 2, 1999
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Reiner Gentz, Guo-Liang Yu, Craig A. Rosen
  • Cytostatin III nucleic acids encoding
    Patent number: 5945309
    Abstract: The invention relates to Cytostatin III polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: August 31, 1999
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Guo-Liang Yu, Reiner Gentz, Patrick J. Dillon
  • Human cystatin F
    Patent number: 5919658
    Abstract: The invention relates to cystatin F polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: July 6, 1999
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Haodong Li, Guo-Liang Yu, Reiner L. Gentz
  • Polynucleotides encoding extra cellular/epidermal growth factor HCABA58X polypepides
    Patent number: 5916769
    Abstract: The present invention discloses a novel cDNA isolated from human osteoclastoma tissue which encodes a novel polypeptide identified herein as Extracellular/Epidermal Growth Factor HCABA58X owing in part to the presence in its amino acid sequence of epidermal growth factor (EGF) domains characteristic of the EGF family of polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides. Also disclosed are antagonists against such polypeptides and their uses. Also disclosed are diagnostic assays for detecting altered levels of the polypeptides of the present invention and mutations in the nucleic acid sequences which encode such polypeptides.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: June 29, 1999
    Assignee: Human Genome Sciences, Inc.
    Inventors: Henrik S. Olsen, Steven M. Ruben