Patents Represented by Attorney Joseph T. Majka
  • Patent number: 6136818
    Abstract: A method of treating sexual dysfunction comprising administering a therapeutically effective amount of a combination of phentolamine and apomorphine, as well as pharmaceutical compositions and kits useful in those methods, are disclosed.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: October 24, 2000
    Assignee: Schering Corporation
    Inventor: Thomas Mark Estok
  • Patent number: 6071907
    Abstract: Novel tricyclic compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel tricyclic compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.
    Type: Grant
    Filed: September 11, 1997
    Date of Patent: June 6, 2000
    Assignee: Schering Corporation
    Inventors: F. George Njoroge, Yi-Tsung Liu, Arthur G. Taveras
  • Patent number: 6011043
    Abstract: A method of treating sexual dysfunction comprising administering a therapeutically effective amount of a combination of phentolamine and apomorphine, as well as pharmaceutical compositions and kits useful in those methods, are disclosed.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: January 4, 2000
    Assignee: Schering Corporation
    Inventor: Thomas Mark Estok
  • Patent number: 6001845
    Abstract: A method of treating sexual dysfunction comprising administering a therapeutically effective amount of a combination of phentolamine and apomorphine, as well as pharmaceutical compositions and kits useful in those methods, are disclosed.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: December 14, 1999
    Assignee: Schering Corporation
    Inventor: Thomas Mark Estok
  • Patent number: 5965570
    Abstract: Novel tricyclic compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel tricyclic compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human.
    Type: Grant
    Filed: September 11, 1997
    Date of Patent: October 12, 1999
    Assignees: Schering Corporation, Pharmacopeia Inc.
    Inventors: Alan B. Cooper, Alan K. Mallams, Viyyoor M. Girijavallabhan, Ronald J. Doll, Arthur G. Taveras, F. George Njoroge, John J. Baldwin, John C. Reader
  • Patent number: 5965735
    Abstract: Process for preparing a key intermediate, 2-methyl-3-trifluoromethylaniline (MTA) of Flunixin, as well as novel intermediates thereof are described.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: October 12, 1999
    Assignee: Schering Corporation
    Inventors: Henry J. Doran, Donal J. Coveney
  • Patent number: 5958940
    Abstract: Novel tricyclic compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel tricyclic compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.
    Type: Grant
    Filed: September 11, 1997
    Date of Patent: September 28, 1999
    Assignee: Schering Corporation
    Inventors: Dinanath F. Rane, Alan B. Cooper, Alan K. Mallams, Ronald J. Doll, F. George Njoroge, Arthur G. Taveras
  • Patent number: 5958397
    Abstract: The present invention is directed towards a method, a composition and an article of manufacture for protecting the skin from jellyfish stings. The method comprises topically contacting the skin with a composition containing polymeric quaternary ammonium salt in amounts sufficient to protect against the rupture of jellyfish nematocysts. The composition can be in the form of an emulsion, liquid dispersion, solution, skin cream, face cream, lotion or ointment.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: September 28, 1999
    Assignees: Schering-Plough HealthCare Products, Inc., University of Maryland, Baltimore
    Inventors: Richard V. Smerbeck, James R. Johnson, Joseph W. Burnett, Jennifer E. Purcell
  • Patent number: 5948688
    Abstract: A method of analyzing pharmaceutically useful suspensions of lipophilic oligosaccharide antibiotics by QLS is disclosed.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: September 7, 1999
    Assignee: Schering Corporation
    Inventors: Patricia C. Weber, Ashit K. Ganguly, Eric W. Kaler
  • Patent number: 5948392
    Abstract: Stable sulfide-containing compositions have been developed. The stable sulfide-containing composition comprises a) a sulfide, a polysulfide or mixtures thereof, of an alkali or an alkaline earth metal, and b) a carrier, such that after maintaining the sulfide-containing composition at a temperature of about 37.degree. to about 50.degree. Celsius for about 2 weeks to one month, the sulfide content remaining in the sulfide-containing composition is about 90% or greater of the initial sulfide content. The sulfide-containing compositions can be used for relieving the pain of ingrown toenail by softening the nail, or as a depilatory for removing human hair or hair from animal hides.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: September 7, 1999
    Assignee: Schering-Plough HealthCare Products, Inc.
    Inventors: Joseph A. Haslwanter, Gerald R. Dever, Thomas J. Laughlin
  • Patent number: 5945430
    Abstract: Novel aminooxyamide tricyclic compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide tricyclic compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: August 31, 1999
    Assignee: Schering Corporation
    Inventors: Ronald J. Doll, Tarik Lalwani
  • Patent number: 5925648
    Abstract: Novel tricyclic N-cyanoimine compounds and pharmaceutical compositions of formula (1.0) ##STR1## or a pharmaceutically acceptable salt or solvate thereof, wherein a, b, c, d, R.sup.1 -R.sup.8, X and Z are defined herein. Such compounds are inhibitors of the enzyme, farnesyl protein transferase. The compounds are useful for inhibiting Ras function and therefore inhibiting the abnormal growth of cells, in a mammals such as a human.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: July 20, 1999
    Assignee: Schering Corporation
    Inventors: Alan B. Cooper, James J-S Wang, Raymond G. Lovey, Jagdish A. Desai, Anil K. Saksena, Viyyoor M. Girijavallabhan, Ronald J. Doll
  • Patent number: 5922470
    Abstract: An article comprising a soft, polysiloxane elastomer having a hardness of 5-55 durometer units (Shore 00), the elastomer having a pressure sensitive adhesive on at least one of its surfaces is described. A process for bonding a pressure sensitive adhesive to the soft polysiloxane elastomeric is also described.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: July 13, 1999
    Assignee: Schering-Plough HealthCare Products, Inc.
    Inventors: Ronald L. Bracken, Gerald R. Dever, Ronald M. Feret, Daniel B. Snyder
  • Patent number: 5895679
    Abstract: An novel egg holder is claimed. The egg holder is used in combination with a tray and dye containing liquid for coloring eggs.
    Type: Grant
    Filed: May 30, 1997
    Date of Patent: April 20, 1999
    Assignee: Schering-Plough HealthCare Products, Inc.
    Inventors: John C. Pender, Charles Wood Saunders, Jr., Daniel Robert Williams, James S. Mandle
  • Patent number: 5880128
    Abstract: Novel carbonyl piperazinyl and piperidinyl compounds and pharmaceutical compositions are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel carbonyl piperazinyl or piperidinyl compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: March 9, 1999
    Assignees: Schering Corporation, Pharmacopeia Inc.
    Inventors: Ronald J. Doll, Alan K. Mallams, Adriano Afonso, Dinanth F. Rane, George F. Njoroge, Randall R. Rossman, John J. Baldwin, Ge Li, John C. Reader
  • Patent number: D414024
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: September 21, 1999
    Assignee: Schering-Plough HealthCare Products
    Inventors: Albert Kress, Harold A. Howlett
  • Patent number: D422358
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: April 4, 2000
    Assignee: Schering-Plough Healthcare Products, Inc.
    Inventors: Charles E. Lundy, Jr., Jerome D. Muchin, Gary C. Wildman
  • Patent number: D422702
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: April 11, 2000
    Assignee: Schering-Plough Healthcare Products, Inc.
    Inventors: Charles E. Lundy, Jr., Jerome D. Muchin, Gary C. Wildman, Ronald M. Feret
  • Patent number: D422703
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: April 11, 2000
    Assignee: Schering-Plough Healthcare Products, Inc.
    Inventors: Charles E. Lundy, Jr., Jerome D. Muchin, Gary C. Wildman
  • Patent number: D422782
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: April 18, 2000
    Assignee: Schering Corporation
    Inventors: Albert Kress, Harold A. Howlett