Patents Represented by Attorney Judy M. Iota Pi Law Group Mohr

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  • Composition and method for dermal and transdermal administration of a cytokine
    Patent number: 6165458
    Abstract: A composition for transdermal administration of a cytokine is described. The composition includes a conjugate composed of a cytokine, such as an interferon, and at least one fatty acid moiety covalently attached to the cytokine. The conjugate has enhanced cutaneous delivery relative to the cytokine alone.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: December 26, 2000
    Assignee: PharmaDerm Laboratories Ltd.
    Inventors: Marianna Foldvari, Sam Kwadwo Attah-Poku
  • Isozyme-specific activators of protein kinase C methods and compositions
    Patent number: 6165977
    Abstract: Isozyme-specific agonists or activators of .epsilon.PKC are disclosed. The agonists include peptides corresponding to the region of .epsilon.PKC between about amino acids 85 and 92. Also disclosed are therapeutic methods employing such .epsilon.PKC-specific agonists to induce preconditioning and thereby reduce injury due to subsequent ischemia, as well as methods for screening test compounds for .epsilon.PKC-selective agonist properties.
    Type: Grant
    Filed: October 17, 1997
    Date of Patent: December 26, 2000
    Assignee: Board of Trustees of the Leland Stanford Junior University
    Inventor: Daria Mochly-Rosen
  • Magnetic recording medium having a nitrogen-containing barrier layer
    Patent number: 6146737
    Abstract: A magnetic recording medium having a barrier layer deposited directly on the magnetic recording layer is described. The barrier layer is deposited by sputter deposition under a nitrogen-containing sputtering atmosphere to form a nitrogen-containing chromium or chromium alloy barrier layer. The barrier layer is effective to inhibit migration of cobalt from the underlying magnetic recording layer, reducing corrosion of the medium and improving magnetic recording performance.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: November 14, 2000
    Assignee: HMT Technology Corporation
    Inventors: Sudhir S. Malhotra, Brij Bihari Lal, James L. Chao, Michael A. Russak
  • Liposomes containing a cisplatin compound
    Patent number: 6126966
    Abstract: A liposome composition containing an entrapped cisplatin compound is described. The liposomes have a surface coating of hydrophilic polymer chains on inner and outer surfaces and an entrapped cisplatin compound. The compound is entrapped with substantially greater retention in the liposomes, when compared to liposomes lacking the polymer coating. A method of preparing the composition is also described.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: October 3, 2000
    Assignee: Sequus Pharmaceuticals, Inc.
    Inventors: Robert M. Abra, Karen Reis
  • Cell membrane fusion composition and method
    Patent number: 6099857
    Abstract: A lipid vesicle composition for use in delivering a vesicle-encapsulated agent to a target cell is disclosed. The composition is formed of vesicle-forming lipids, including at least 10 mole percent plasmalogen phospholipid with a small-volume polar head group. The composition may also include a fusion protein for promoting fusion of the vesicles to the target cells. A novel fusion protein identified as an isoform of glyceraldehyde-3-phosphate dehydrogenase is also disclosed.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: August 8, 2000
    Assignee: Washington University
    Inventor: Richard W. Gross