Patents Represented by Attorney Karol Pessin

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  • Stem cell factor formulations and methods
    Patent number: 6020469
    Abstract: Disclosed is a method of preparing a lyophilized stem cell factor (SCF). The method comprises mixing the SCF with histidine and/or glutamic acid and lyophilizing the formulation. Optionally, a bulking agent or an osmolarity regulating agent is included in the formulation prior to lyophilization.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: February 1, 2000
    Assignee: Amgen Inc.
    Inventor: Susan I. Hershenson
  • Computer apparatus for expressing a three dimensional structure of a G-CSF molecule or analogs thereof
    Patent number: 5790421
    Abstract: The present invention is directed towards a computer apparatus for expressing a three dimensional structure of a G-CSF molecule or analogs thereof.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: August 4, 1998
    Assignee: Amgen Inc.
    Inventor: Timothy David Osslund
  • Computer-based methods and articles of manufacture for preparing G-CSF analogs
    Patent number: 5581476
    Abstract: Provided are computer-based methods for preparing G-CSF analogs involving (a) providing computer expression of the three dimensional structure of a G-CSF molecule wherein the chemical moieties, such as each amino acid residue or each atom of each amino acid residue of the G-CSF molecule are correlated with said structure: (b) selecting from said computer expression a site on a G-CSF molecule for alteration; and (c) preparing a G-CSF molecule having such alteration. Also provided are articles of manufacture associated with such methods.
    Type: Grant
    Filed: January 28, 1993
    Date of Patent: December 3, 1996
    Assignee: Amgen Inc.
    Inventor: Timothy D. Osslund