Abstract: The present utility model relates to submersible motor and its protector. A shared assembling base is provided to support and fix one end of the housing of the submersible motor and protector, the submersible motor has a main shaft to connect through the protector. The end of the assembling base connecting with the protector has a thrust bearing to support the motor shaft and form a thrust bearing chamber with the seal base of the protector, the shared assembling base has a cooling oil connecting passage, the isolation chamber where the bag is put in is formed between the seal base and assembly head base of the protector, a mechanical seal outside the assembly head base is provided for acting on the main shaft.

Abstract: This invention provides a method for treating a cancer subject comprising administering to the subject a combination of ATP-depleting agents at concentrations which deplete the ATP level to at least 15% of normal in cancer cells, a pyrimidine antagonist, and an anticancer agent to which the treated cancer is sensitive. This invention also provides a composition comprising a combination of ATP-depleting agents at concentrations which deplete the ATP level to at least 15% of normal in cancer cells, a pyrimidine antagonist, and an anticancer agent to which the treated cancer is sensitive. Finally this invention provides a pharmaceutical composition comprising the above composition or a combination thereof and a pharmaceutically acceptable carrier.

Abstract: The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic modification in a biosynthetic pathway gene such as the purl gene. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.

Abstract: A tool holder includes a base body having a through hole and a tubular clamp rotatable between first and second positions. The tubular clamp has a plurality of axially extending split parts which extend through the through hole and which define a clamping hole to clamp a cutter. The split parts are resilient to move inward or outward. A plurality of push elements are formed on the base body to push the split parts inward when the tubular clamp is in the first position. The split parts are released when moving from the push elements in the second position of the tubular clamp.

Abstract: The present invention provides methylenetetrahydrofolate reductase (MTHFR) inhibitors for use in selective inhibition of cancer cell growth in a mammal. These inhibitors can be a small molecule, an antisense oligonucleotide, a ribozyme, a triple helix forming oligonucleotide, an anti-MTHFR antibody or fragment thereof, an MTHFR mutant or a fragment of MTHFR. The present invention further provides nucleic acids encoding an inhibitor of MTHFR, and vectors comprising these nucleic acids. Also encompassed by the present invention are methods of using the MTHFR inhibitors for selective inhibition of cancer cell growth, and pharmaceutical compositions comprising the MTHFR inhibitors.

Abstract: An human antibody anti-NS3 protein of the hepatitis C virus (HCV) is described, as will as synthetic and recombinant fragments thereof able to inhibit the helicase activity of the NS3 protein, both in vitro and in vivo, and uses thereof.

Abstract: This invention provides a method to determine alkylguanyltransferase activity in a sample, comprising steps of placing the sample in an appropriate condition so that the AGT is functional; contacting the sample with an AGT Detector under conditions permitting the binding of AGT and AGTD to produce a signal; and measuring the signal, thereby determining the AGT activity in said sample. This invention provides different uses of this method.

Abstract: Novel compounds such as compounds designated herein as Xanifolia-Y or -Y3, -Y1, -Y2, -Y8, -Y9 and -Y10 are disclosed. These compounds have anticancer activity. The compounds of the present invention are obtainable from plants in the sapindaceae family, such as Xanthoceras sorbifolia, or other natural sources or products.

Abstract: A group of compounds that inhibit HIV replication by blocking HIV entry was identified. Two representative compounds, designated NB-2 and NB-64, inhibited HIV replication (p24 production) with IC50 values <0.5 ?g/ml.

Abstract: This invention provides a brewing head unit of a coffee machine for inserting and locking the filter and the filter holder into the brewing head of a coffee machine. The filter and the filter holder can be inserted into the coffee machine visually. This invention further provides a simpler and easier method for inserting filter holder into a pressurized coffee machine. This invention also provides a cabinet filter holder which can be inserted or placed into the brewing head assembly/unit of a coffee machine by sliding the filter holder into the brewing head unit from front or side; by swinging the filter holder into the brewing head assembly/unit on a pivot; or by inserting the filter holder from the top. This invention further provides a brewing head assembly/unit wherein the locking mechanism is motor-driven. In one aspect of this invention, the method for opening and closing the brewing head assembly/unit of the coffee machine can be operated by remote control.

Abstract: Disclosed herein is a process for enhancing anaerobic biohydrogen production, including: adding into a reactor an organic waste containing hydrogen-producing anaerobic bacteria, a first substrate, and a carrier that permits the hydrogen-producing anaerobic bacteria to adhere and grow thereon, so as to form a mixture; acclimating the mixture at a first agitation speed ranging from 5 to 60 rpm, so that the hydrogen-producing anaerobic bacteria adhere to and proliferate on the carrier, followed by the formation of granular biomasses within the acclimated mixture; and feeding a second substrate into the reactor at a second agitation speed ranging from 5 to 60 rpm, so that the content of the granular biomasses is increased while the second substrate is anaerobically fermented by the hydrogen-producing anaerobic bacteria in the granular biomasses to result in the production of hydrogen.