Patents Represented by Attorney Laydig, Voit & Mayer, Ltd.
  • Patent number: 6660521
    Abstract: The present invention provides a method of modulating the persistence of expression of a transgene in an at least E4&Dgr; adenoviral vector in a cell. In one embodiment, the method comprises contacting the cell with an at least E4&Dgr; adenoviral vector comprising (i) a transgene and (ii) a gene encoding a trans-acting factor, which is not from the E4 region of an adenovirus and which modulates the persistence of expression of the transgene. In another embodiment, the method comprises contacting the cell simultaneously or sequentially with (i) an at least E4&Dgr; adenoviral vector comprising a transgene and (ii) a viral vector comprising a gene encoding a trans-acting factor, which is not from the E4 region of an adenovirus and which modulates the persistence of expression of the transgene. In addition, the present invention provides a recombinant at least E4&Dgr; adenoviral vector for use in the method and a composition comprising the vector and a carrier therefor.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: December 9, 2003
    Assignee: GenVec, Inc.
    Inventors: Douglas E. Brough, Imre Kovesdi
  • Patent number: 4621477
    Abstract: An assemblable temporary wall unit construction for industrial buildings wherein horizontally spaced vertical H-beam column members receive, a plurality of preformed stackable reinforced concrete panels positionable between and bridging the columns, the spacing between said columns being such that the panels can be inserted horizontally by positioning one end of the panel adjacent one of said beam columns, aligning the panel and shifting said panel horizontally to bridge the spaced column beams and wedge-like metal filler members being insertable between the panels and column beams for rigidly holding and confining the panels with respect to the column beams.
    Type: Grant
    Filed: July 18, 1985
    Date of Patent: November 11, 1986
    Inventor: Dennis I. Kinst
  • Patent number: D534908
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: January 9, 2007
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Jong-Seong Lee