Abstract: The present invention provides substituted di-, tri-, tetra- and penta-sulfide compounds and compositions, and methods of using the same for the treatment and/or prevention of a cell proliferative disorder. The present invention also provides methods for preparing trisulfide compounds and compositions.

Abstract: Provided is a semiconductor laser device that is free from or suffers less from deterioration resulting from a surge or that is less likely to suffer from deterioration resulting from a surge. The semiconductor laser device has a conductive stem 101, a submount 102 fixed to the stem 101, a nitride semiconductor laser chip 103 mounted on the submount 102, pins 104 and 105 fixed to the stem 101 but insulated therefrom, a wire connecting the pin 104 to a p-electrode of the nitride semiconductor laser chip 103, a wire connecting the pin 105 to an n-electrode of the nitride semiconductor laser chip 103, and a cap 106 enclosing the nitride semiconductor laser chip 103 and the submount 102 and fixed to the stem 101.

Abstract: An audio signal processing apparatus comprises input channels, a mix bus, a volume level controller, a path disconnector that connects or disconnects a path from each input channel to the mix bus, a signal selector that select either one of a post-signal and a pre-signal, a volume adjusting operator that groups at least a part of the plurality of input channels and collectively adjusts volume levels of the grouped input channels, a mute setting device that sets muting of the grouped input channels, a mute target selector that selects either one of a first mode in which only the post-signal is muted and a second mode in which both pre-signal and post-signal are muted, and a mute controller that controls, when the mute setting device has set muting of the grouped input channels, the volume level controller to execute the muting of the grouped input channels on the first mode, and controls the path disconnector to execute the muting of the grouped input channels on the second mode.

Abstract: A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X3 and X4 are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I).

Abstract: In an acoustic design support apparatus, a speaker selection supporter selects a desired speaker as a candidate for use in a given space based on shape information representing a shape of the space. A speaker mounting angle optimizer calculates an optimal mounting direction of the selected speaker by selecting a mounting direction pattern which minimizes a degree of variation among sound pressure levels at a plurality of positions on a sound receiving surface defined in the space. An acoustic parameter calculator calculates a variety of acoustic parameters at sound receiving points within the space based on both of the shape information of the space and the optimal mounting direction of the speaker.

Abstract: The present invention improves projection displays of volume data. Using the Minimum Intensity Projection (MinIP), fluid filled regions or other regions of hyporeflective tissue are displayed. By limiting the projection to partial volumes within the volume, differences in the scattering intensity within specific regions are isolated. In this way, hyperreflectivity of weakly scattering tissue can be assessed.

Abstract: A wand assembly for a cleaning appliance includes a handle portion having a channel formed therethrough; a tubular wand received within the channel and moveable between a first position and a second position; a locking mechanism having a lock position and an unlock position and preventing the wand from moving from the first position when in the lock position; and a release mechanism mounted to the wand and which can be actuated to move the locking mechanism from the lock position to the unlock position. The release mechanism is actuated by relative movement of the release mechanism with respect to the wand.

Abstract: The invention reduces unnecessary electromagnetic radiation noise due to an operation clock signal generated by an oscillator circuit. Random number data outputted by a random number generation circuit is stored in a frequency variable data register. The data stored in the frequency variable data register is replaced by random number data sequentially generated by the random number generation circuit. An oscillator circuit is a circuit generating a clock signal, and the clock signal is supplied as an operation clock signal to an internal circuit through an operation clock signal generation circuit. The frequency of the clock signal from the oscillator circuit is variably controlled in response to the random number data stored in the frequency variable data register. A frequency variable range control register which stores control data for controlling the range of the frequency variably controlled in response to the random number data stored in the frequency variable data register is further provided.

Abstract: Provided herein are various schemes for transmitting out of band (OOB) signals over optical connections that may not support the transmission of such signals. One scheme may involve converting the OOB signals to different types of signals that are supported by the optical connection, while another scheme may utilize a separate parallel connection that supports the transmission of out of band signals in order to extend the optical connection. Yet another scheme modulates the reference clock of the original (in-band) signal to transmit and receive the OOB information.

Abstract: A semiconductor device includes a plurality of first output terminals 1-13 and a plurality of first output circuits 203,204 provided corresponding to each of the plurality of first output terminals and coupled to a corresponding first output terminal. The semiconductor device further includes a second output circuit 201 coupled to a second output terminal DQS. The second output circuit automatically adjusts a slew rate based on the state transitions of the plurality of first output circuits. The second output circuit adjusts the slew rate from a first state to a second state based on a transition from first data outputted from the first output circuit to second data following said first data. The second output circuit outputs data in synchronization with the second data with a slew rate in said second state.

Abstract: A surface treating appliance, such as a vacuum cleaner, includes a device generating a flow of fluid in the form of a motor and fan, housed in a main body. A hose and wand assembly, a surface treating head and a rotary change over valve are also provided. The valve is selectively rotatable so as to allow fluid flow from either the surface-treating head or the hose. A support assembly is moveable between a supporting position, in which it supports the main body, and a retracted position. The change over valve and support assembly are arranged so that motion of the support assembly between the supporting and retracted positions induces rotary motion of the change over valve.

Abstract: Compact input devices formed on flexible substrates are disclosed. The input devices may be formed using three or more conducting layers. By including three or more conducting layers, the diameter of the input device may be minimized. In addition, to improve the flexibility of portions of the input device mounted, some portions of the input device may be made to have fewer layers than other portions of the input device.

Abstract: The invention is directed to a positive airway pressure (PAP) system with a head mounted harness assembly with a housing and a head position sensor located within or secured to the housing that detects the position of a patient's head, and communicates this head position information to a controller of the system which may be disposed within the housing having the position sensor or a second housing. The controller varies the output pressure of the pressure source, e.g. a rotary compressor, based, at least in part, on the head position information provided by the head position sensor. In a preferred embodiment, the position sensor is an accelerometer.

Abstract: Calculation is performed for sound paths 112-1, 114-1 along which sounds emitted from a sound emitting point 104 in an acoustic space 102 are reflected and delivered to a sound receiving point 106. By the calculation, entering angles eR1, eR2 by which the sound paths enter the front side 106a of the sound receiving point 106 are obtained. Calculation is then performed to obtain angles by which respective speakers 52C, 52L, 52R, 52SR, 52SL of a 5.1 surround system are arranged in a listening room, with the front side 106a of the sound receiving point 106 centered thereon. Audio signals on the respective sound paths are distributed among channels for any two speakers. Consequently, sharp localization of sound images is achieved, requiring less calculation in simulating acoustic characteristics of the acoustic space 102 in which the sound emitting point 104 for emitting sounds and the sound receiving point 106 for receiving the sounds are placed.

Abstract: The present invention relates to novel methods and compositions useful for detecting whole parathyroid hormone at a physiological level and parathyroid fragments in a mammalian sample. Such detections may be useful to different parathyroid diseases or disorders in a subject, such as hyperparathyroidism and related bone diseases, from normal or non-disease states. One detects whole or non-fragmented (1 to 84) parathyroid hormone in a biological sample and optionally one or more of a selection of non-whole parathyroid hormone peptide fragments that may or may not function as a parathyroid hormone antagonists. By either comparing values or using independently the value of either the one or more of a selection of non-whole parathyroid hormone peptide fragments, the whole parathyroid hormone, or the combination of these values one is able to differentiate parathyroid and bone related disease states, as well as differentiate such states from normal states.

Abstract: Apparatus and methods are disclosed for simultaneously tracking multiple finger and palm contacts as hands approach, touch, and slide across a proximity-sensing, multi-touch surface. Identification and classification of intuitive hand configurations and motions enables unprecedented integration of typing, resting, pointing, scrolling, 3D manipulation, and handwriting into a versatile, ergonomic computer input device.

Abstract: Advertising data is incorporated into predictively encoded, for example MPEG encoded, digital video representing a video feature such as a film or movie or television show or program or video game by re-encoding one or more sequences or groups of pictures of the video feature with reference to at least one frame of advertising data representing at least one advertisement so that the sequence of the video feature cannot be decoded without decoding the advertising data, thereby making it difficult, when the video feature is delivered to an end user by, for example, downloading or streaming over a network, for the end user to skip or delete the at least one advertisement from the video feature, without detrimentally affecting the video feature.

Abstract: This invention provides a motor drive circuit, which makes it possible to prevent braking when a power supply voltage is lower than a predetermined voltage while suppressing at a low cost a rise in a voltage on a power supply line when a kickback occurs. The motor drive circuit is formed to include first and second power supply lines connected with and shunted from a power supply, an H-bridge circuit, and a means to control the H-bridge circuit. The means controls the H-bridge circuit so that a regeneration path is not created in the H-bridge circuit when the power supply voltage is lower than a predetermined voltage.

Abstract: The present invention relates to an interlabial pad which is attached between female labia, especially to the pad which can be used together with the sanitary napkin, which has a good sealing efficiency with the labia deepest portion when the user moves and can prevent the chance that the leak of the menstrual blood or the dropping off of the pad is occurred. Further the interlabial pad comprises the absorbing sheet portion facing to the body side upon wearing the pad and the support sheet portion backing the absorbing sheet portion.