Abstract: A method of treating pain in a warm-blooded animal comprising administering to anwarm-blooded animal in need thereof an amount of a compound of the formula wherein the substituents are defined in accordance with the disclosure.
Type:
Grant
Filed:
July 26, 2004
Date of Patent:
October 17, 2006
Assignee:
Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
Inventors:
Pierre Etienne Chabrier de Lassauniere, Serge Auvin, Dennis Bigg, Michel Auquet, Jeremiah Harnett
Abstract: An electrophotographic image forming method is disclosed. A latent image on a photoreceptor is developed to form a toner image on the photoreceptor by a developer and the toner image is transferred to a recording material or an intermediate transfer element, and the developing and the transferring are performed while regulating a contact angle of the photoreceptor with water within ±5° of an average contact angle by applying a surface energy-lowering agent on the surface of the photoreceptor.
Abstract: The invention concerns a colloidal dispersion, in an organic solvent, of a microfibrillated and/or microcrystalline particles of a fibrillated organic substance selected among the group consisting of cellulose, chitin, polysaccharides such as ?1?3 glucan, ?1?3 xylan and ?1?4 mannan, further containing a compound having a hydrophilic part and a hydrophobic part.
Type:
Grant
Filed:
June 13, 2000
Date of Patent:
November 22, 2005
Assignee:
Centre National de la Recherche Scientifique
Abstract: Double-pass pushbutton, able to act successively on one or both independent microswitches (M1), (M2), where the body shell and the pushbutton have a leaktight and flexible cap mounted between them, which hermetically seals the joint without interfering with the guided axial movement of the pushbutton, with respect to the body to be activated, or stopping the operator's action; it has two contact stops at different heights, for their successive contact with the relative rnicroswitches when moved linearly; and there are means between the body shell and the pushbutton for the successive positioning of the pushbutton. The pushbutton is especially useful in control pushbutton panels.
Type:
Grant
Filed:
June 19, 2002
Date of Patent:
November 22, 2005
Assignee:
Angel Iglesias, S.A.
Inventors:
Luis Rodriguez Navarrete, Domingo Revilla Asensio
Abstract: A reusable bacteria inhibiting hygienic device for vaginal/colon and external genital cleansing suited for use while seated on the toilet or standing in a tub respectively, including a rigid stationary/flexible portable container proficient in delivering a sufficient amount of douche, colon or external cleansing preparation provided with a vented cap, a volume sensitive valve, a retainer cap a short length of tubing with threads attached to retainer, and the other end of short length of tubing attached to the top of a control valve with backflush prevention ballcheck, an adequate length of tubing with one end attached to bottom of control valve and opposite end of adequate length of tubing attached to acessory of choice.
Abstract: The invention relates to a pre-filled injection device for injecting a liquid or semisolid composition into a subject, said injection device comprising: a housing (1) containing at its distal end the liquid or semisolid composition (2), a plunger (3) arranged to slide within the housing (1) to which is affixed a plunger stick (7) extending longitudinally from the plunger to the outside of the housing (1), a hollow needle (4) affixed to the distal end of the housing (1), said needle (4) connecting the interior part of the housing (1) with the outside where it extends longitudinally, and an airtight needle shield (5) which protects said needle (4), characterized in that said device further comprises a cap (6) designed to fit around the housing's proximal end and to fully cover said plunger stick (7), said cap (6) both preventing its accidental pushing or breakage before use and being adapted to receive the injection device once the injection into the subject has been carried out.
Type:
Grant
Filed:
October 22, 2002
Date of Patent:
October 11, 2005
Assignee:
Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S)
Inventors:
Christophe Aubert, Roland Cherif-Cheikh
Abstract: The invention proposes a finger lever (1) of a valve train of an internal combustion engine, said finger lever (1) being switchable to different valve lifts for at least one gas exchange valve and comprising an outer lever (2) having two arms (3a, 3b) between which an inner lever (4) is arranged for pivoting relative to the outer lever (2), which outer and inner levers (2, 4) can be coupled to each other by a coupling means (15), the outer lever (2) comprising on one closed end (5), a support (5a) for a gas exchange valve and the finger lever (1) comprising on an opposite end (6), a complementary surface (7, 30) for a support element, the inner lever (4) having a fulcrum (10) in a region of the opposite end (6), and at least this inner lever (4) comprising a contact surface (11) for a cam.
Type:
Grant
Filed:
January 26, 2005
Date of Patent:
September 27, 2005
Assignee:
INA-Schaeffler KG
Inventors:
Michael Haas, Martin Rauch, Bodo Rörig, Dieter Schmidt, Jens Artmann
Abstract: The present invention relates to cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, the method for preparation and the pharmaceutical composition thereof. The cinnamaldehyde derivatives of the present invention can be effectively used as a cell cycle regulator or a cancer cell growth inhibitor, since it has an ability to regulate cell cycle by holding the cells in G2/M stage of the cell division and has activity to inhibit cancer cell growth.
Type:
Grant
Filed:
May 28, 2004
Date of Patent:
September 27, 2005
Assignee:
Korea Research Institute of Bioscience and Biotechnology
Inventors:
Byoung-Mog Kwon, Kwang-Hee Son, Dong Cho Han, Sangku Lee, Jong Han Kim, Sung-Gyu Choi, Mi-Young Lee, Sun Bok Jeon
Abstract: Disclosed are an organic-inorganic hybrid film comprising a cellulose derivative and a polycondensation product of a condensation polymerizable reactive metal compound, wherein the film contains a plasticizer in an amount of 1 to 20% by weight and its manufacturing method.
Type:
Grant
Filed:
August 13, 2003
Date of Patent:
September 20, 2005
Assignee:
Konica Corporation
Inventors:
Yasushi Okubo, Takahiro Takagi, Yasuo Kurachi, Kaori Ono
Abstract: The invention relates to the use of Ginkgo biloba extracts for preparing a medicament intended to ease the withdrawal of individuals dependent on the consumption of a substance engendering dependency and/or addiction, such as in particular alcohol, amphetamines, tobacco, drugs inducing toxicomania.
Type:
Grant
Filed:
December 1, 1998
Date of Patent:
August 30, 2005
Assignee:
Societe de Conseils de Recherches d'Application Scientifiques (S.C.R.A.S.
Abstract: Polymeric prodrugs of the formula: wherein B is selected from the group consisting of OH, leaving groups, residues of amine-containing moieties and a residues of hydroxyl-containing moieties; Y1 is selected from the group consisting of O, S, and NR5; M is NR3, O or S; Ar is a moiety which when included in Formula I forms a multi-substituted aromatic or heteroaromatic hydrocarbon or a multi-substituted heterocyclic group; (m) is zero or a positive integer; R1-3 and R5 are independently selected from the group consisting of hydrogen, C1-6 alkyls, C3-12 branched alkyls, C3-8 cycloalkyls, C1-6 substituted alkyls, C3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C1-6 heteroalkyls, substituted C1-6 heteroalkyls, C1-6 alkoxy, phenoxy and C1-6 heteroalkoxy; and R4 is a polymeric residue; as well as methods of making and using the same are disclosed.
Abstract: A coating apparatus for a plurality of cylindrical light sensitive members each for use in an electrophotography, is provided with a coating tank in which a coating liquid is stored; a dipping device to lift down the plurality of cylindrical base members into the coating liquid and to lift up the plurality of cylindrical base members above the coating liquid so that the plurality of cylindrical base members are coated with the coating liquid; and a plurality of drying hoods corresponding in number to the plurality of cylindrical base members and provided above the coating tank so that each of the plurality of cylindrical base members is lifted up from the coating tank into a respective drying hood among the plurality of cylindrical base members.
Abstract: The present invention relates to a method for fabricating a functional dental element, such as a crown. According to the invention, use is made of a three-dimensional printing technique. The major advantages of the invention are that no mold is needed anymore, which entails a considerable saving of costs, that a great accuracy is achieved, and that the element can be made of different materials.
Type:
Grant
Filed:
August 24, 2000
Date of Patent:
July 26, 2005
Assignee:
Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO
Abstract: A dispensing apparatus and an aerosol type dispenser therewith for discharging contents stored in a measured chamber effectively. The dispensing apparatus is comprised of a cylindrical portion for providing a circular recess portion which keeps a part of the contents in the measured chamber and a cylindrical skirt for providing a detour in the circular recess portion. The cylindrical portion and/or the cylindrical skirt form grooves so as to make a sectional area for flowing contents smaller. In mode in use, the upstream contents positioned inside space of the cylindrical skirt take a long way around the circular recess portion at high speed and high pressure, therewith contents settled in the circular recess portion are forced to sent to the passage of the valve stem certainly.
Abstract: An electrophotographic photoreceptor is disclosed. The charge transport material comprising a mixture of stereoisomers as a charge transport material and glass transition point Tgb of the binder resin of the charge transport layer and glass transition point Tg1 of the charge transport layer satisfy 100° C.<Tg1 <Tgb (both Tgb and Tg1 in ° C.). An image forming method employing the photoreceptor is also disclosed.
Abstract: The present invention is directed to a solid propellant for rocket motors, gas generators and comparable devices, comprising a cured composition of hydrazinium nitroformate and an unsaturated hydroxyl terminated hydrocarbon compound.
Type:
Grant
Filed:
May 19, 1999
Date of Patent:
July 12, 2005
Assignee:
Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO
Inventors:
Jeroen Louwers, Antonius Eduard Dominicus Maria Van Der Heijden, Petrus Johannes Maria Elands
Abstract: A process for the production of a solid dispersion of at least one therapeutic agent in a hydrophilic carrier having enhanced solubility in an aqueous media comprising dissolving at least one therapeutic agent in a volatile organic solvent containing a very hydrophilic polymer and evaporating the solvent to dryness to form a co-precipitate of therapeutic agent and hydrophilic polymer and the resulting products and their therapeutic method of use.