Abstract: Novel genetic variants of the Angiotensin Receptor 1 (AGTR1) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the AGTR1 gene. Compositions and methods for haplotyping and/or genotyping the AGTR1 gene in an individual are also disclosed. Polynucleotides defined by the sequence of the haplotypes disclosed herein are also described.
Type:
Grant
Filed:
May 30, 2001
Date of Patent:
February 18, 2003
Assignee:
Genaissance Pharmaceuticals, Inc.
Inventors:
Alison E. Anastasio, Kevin Finkel, Beena Koshy, Helen Lee