Abstract: A process is disclosed for the preparation of simvastatin which enables highly regio selective C-methylation of the 2′-position group of lovastatin without requiring protection/deprotection of 13-OH of lovastatin and lactone ring opening/closure.

Abstract: Motorized wheels in a wheelchair or other light vehicle are each mounted on an axle for limited rotation relative to a secondary connection to the frame of the vehicle which incorporates a sensor providing feedback which controls the motor according to torque sensed through the secondary connection. The motor and associated gearing and control circuitry are housed within a wheel hub of which a drum supporting a wheel rim is supported at its inner surface on multiple bearings spaced around its periphery.

Abstract: A process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives of general formula I: or their pharmaceutically acceptable salts, wherein the meaning of X is hydrogen, carboxyl, alkoxycarbonyl, aryloxycarbonyl, nitrile, or carbamoyl of formula wherein R1 and R2 can be individually or simultaneously hydrogen, alkyl or part of a heterocyclic structure; Z can be hydrogen, halogen, alkyl, aryl, aryloxy or alkoxy group.

Abstract: Solid pharmaceutical compositions comprising cefuroxime axetil as active ingredient and a zinc salt as stabilizer.

Abstract: A retractable screen is located within a frame portion of a window. The screen accumulates on and pays out from a spring biased roller located in said frame portion. The screen is fully retractable and for the most part hidden for viewing, egress or cleaning purposes, and is available as desired when moved to the operable position. The screening material utilized includes “T” shaped members for easy installation in compatible grooves provided with the handle and the roller.

Abstract: The bioavailability of fenofibrate is improved by making a solid dispersion of a disentegrant in the fenofibrate. Method of making said solid dispersion comprising melting the fenofibrate, blending the disintegrant into the melt, and resolidifying the mixture.

Abstract: A process is provided for the preparation of compounds of formula I, useful in the preparation of compounds such as Omeprazole, Lansoprazole and Pantoprazole, wherein R1=H or CH3, R2=H or CH3, R3=Alkoxy (1-4C), OCH2CF3, Cyano, Hydrogen, Halogen, Acetoxy or Aryloxy, any electron withdrawing group or salts (organic or inorganic) of electron donating groups, R=Alkoxy, Hydroxy, Halogen, Activated ester, Tosylate, Mesylate, Thiol or Xanthyl, wherein the process for the preparation of compound of formula I employs a free radical reaction to functionalize the 2-position.

Abstract: Paroxetine hydrochloride anhydrous designated as Form IV having at least one, some or all of the following characteristics: a) Infrared spectra as shown in FIG. 1 and 2, b) A X-ray powder diffraction pattern as shown in Schedule “C”, c) A melting point of between about 80°0 C. to about 95° C.

Abstract: A roll screen cassette is provided for installation in a closure assembly which has a frame for moveably retaining a closure member. The frame includes a header, sill, and vertical jamb sections. At least one of the sections includes a pocket formed within its interior. The pocket having a first predetermined configuration defined by the interior of the section and for receipt of the roll screen. The roll screen including a pair of brackets from which said roll screen is pivotally supported. The pair of brackets having a second predetermined configuration compatible with the pocket of the frame section having the first predetermined configuration. The pair of brackets utilized for removeably retaining the roll screen within the pocket in use.

Abstract: A process for separating diastereomeric mixtures of compounds of formula 1 and formula 2 wherein R1=H or R1 denotes a carboxyl-esterifying group selected from C1-C6 alkyl and C7-C8 aralkyl, by treating the mixture of 1 and 2 with a solvent or mixture of solvents to obtain a substantially pure compound of formula 1.

Abstract: A corner block joined at the side edges thereof and including two mirror image blocks joined at said edge, each of said blocks having a pair of exposed faces, at least one of said faces including a removable portion separated from said block by a scoreline so as to allow an installer to remove said removable portion, wherein said corner block may present a pair of smooth faces when exposed, or alternatively a smooth and a rough split face as exposed, wherein said blocks including key-receiving key ways disposed proximate the top and bottom thereof.

Abstract: A compound of the formula A, wherein R* is a chiral auxiliary, and where the configuration at the asymmetric carbon atom between oxygen and sulfur is (R), (S), or combinations of (R) and (S), useful in the preparation of enantiomerically enriched 1,3-oxathiolane nucleoside analogues, for example (−)-FTC and 3TC.

Abstract: A solution for oral administration comprising intraconazole or saperconazole, an acid, an alcoholic co-solvent.

Abstract: This valve uses a rotatable balancing chamber to control the waterflow into the balancing chamber. A pair of exit ports on the rotatable balancing chamber are in communication with the balancing chambers on either side of a diaphragm equipped shuttle to control the outlet mixture of hot and cold water. The diaphragm equipped shuttle responds to changes in pressure in the respective balance chambers to throttle the water through the valve in response to changes in inlet pressures. The pressure balancing chambers are isolated from the water supplies feeding the valve when the valve is in the “off” position, and the pressure balancing chambers are pre-pressurized before any water is permitted to exit from the valve.

Abstract: A process for manufacturing Simvastatin is provided comprising reacting lovastatin with an organic boronic acid to produce a derivative of lovastatin (lovastatin phenylboronate) methylating the 2-methylbutyryloxy group on the lovastatin derivative to form a 2,2-dimethylbutyryloxy group on the lovastatin derivative and thereafter removing the boronate group to produce simvastatin.

Abstract: A system of connectors for use in temporary structures to connect the bracing members of open lattice towers and trusses to the legs of towers and chords of trusses and space frames. A connector is permanently fitted to each end of all bracing members. The connector is configured to engage a cylinder (or projection) that is integral to the leg (or chord as the case may be). After one end is engaged on a cylinder (projection) the member is rotated about the engaged end until the connector on the opposing end of the member engages a corresponding cylinder (projection) on the opposed leg or chord. Installation of the next member using the method as described permanently locks the previously installed member in place such that it can not be removed until the member that was installed after it is removed. The assembly sequence is therefore fixed and begins at the bottom of a tower leg or one end of a truss chord. Disassembly requires following a sequence that is exactly the reverse of the assembly sequence.

Abstract: This invention provides a safety mechanism for a winch assembly when storing a load, such as a tire under a vehicle or a boat on a trailer, in a raised or stored position. The invention finds particular application to a spare tire, but those skilled in the art will appreciate the broader benefits of such a structure when used with a winch assembly for other uses such as a boat winch for a trailer or any analogous use wherein it is desirable to secure a load in the raised or stored position. A unique actuator is described with an improvement of the invention, which includes a control path therewith to control a rod end and thereby actuates in a preferred embodiment a latch by converting rotary motion to linear motion.

Abstract: A multiple vehicle position cantilevered lift comprising a stiff support for a cantilevered lift, said support being sized so as to be resistant to twist and torque loads, said support having a base plate with openings for selective alignment with openings provided in a concrete floor or footing, the openings in said floor having disposed therein an anchoring member comprising a compressible sleeve having a predetermined diameter and a threaded piston, having a predetermined diameter slightly larger than the cylinder and being contained in said sleeve and having a threaded internal or interior wall for receiving an anchor bolt and having a substantially tapered outer wall wherein as the bolt is fastened to a predetermined torque, the piston rises in the sleeve and expands the sleeve compressing the sleeve outwardly against the concrete surrounding the opening to anchor the sleeve and the bolt in the base plate, said support including framework to movably engage and support at least one cantilevered vehicle li

Abstract: A roll screen cassette for installation in a closure assembly having a frame for moveably retaining a closure member, the frame including a header, sill, and vertical jamb sections, at least one of the sections including a pocket formed within the interior thereof, the pocket having a first predetermined configuration defined by the interior of the section and for receipt of the roll screen, the roll screen comprising a pair of brackets from which the roll screen is pivotally supported, the pair of brackets having a second predetermined configuration compatible with the pocket of the frame section having the first predetermined configuration, the pair of brackets utilized for removeably retaining the roll screen within the pocket in use, the pair of brackets and roll screen being removeably held in position with respect to said frame only by the pocket having the first predetermined configuration and the pair of brackets having a second predetermined configuration compatible with the pocket and being located