Patents Represented by Attorney Nicole A. Beeler

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  • Cyanoalkylamino derivatives as protease inhibitors
    Patent number: 7371747
    Abstract: The present invention is directed to novel cyanoalkylamino derivatives that are inhibitors of cysteine protease such as cathepsins K, S, B and L, in particular cathepsin K Pharmaceutical composition comprising these compounds, method of treating diseases mediated by unregulated cysteine protease activity, in particular cathepsin K utilizing these compounds and methods of preparing these compounds are also disclosed.
    Type: Grant
    Filed: November 13, 2002
    Date of Patent: May 13, 2008
    Assignee: Merck Frosst Canada & Co.
    Inventors: Cameron Black, Sheldon N. Crane, Dana Davis, Eduardo L. Setti