Patents Represented by Attorney, Agent or Law Firm Nilles & Nilles, S.C.
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Patent number: 6280939Abstract: DNA sequencing is performed in real time using an atomic force microscope (AFM). The AFM's probe detects motions that occur when a polymerase incorporates nucleotides into a growing polynucleotide chain and a newly formed double-stranded polynucleotide helix translocates (or “ratchets”) through the polymerase's reaction site. These motions generate a mechanical force that is reflected, either directly or indirectly, by motion of the AFM cantilever. The resulting changes in cantilever motion are detected and can be recorded as an indication that a nucleotide has been incorporated into the DNA template. To determine which nucleotide type has been incorporated, a characteristic of the incorporation of at least one nucleotide type of interest is flagged so as to be distinguishable from the corresponding characteristics of the incorporation of nucleotides of other types.Type: GrantFiled: September 1, 1998Date of Patent: August 28, 2001Assignee: Veeco Instruments, Inc.Inventor: Michael J. Allen
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Patent number: 6272130Abstract: Systems and methods for time division multiplexing are described. A time division multiplexer-demultiplexer system includes I) a signal transmitting system for transmittal of a serialized signal including A) latency free continuous data and B) at least one member selected from the group consisting of bursty data and packetized data, the signal transmitting system including a multiplexer and a timing control block; and II) a signal receiving system for reception of the signal without disrupting the laminarity of the latency free continuous data, the signal receiving system including a demultiplexer and a sequence detector. The systems and methods provide advantages in that continuous data can be simultaneously transmitted with bursty data and/or packetized data on the same tie line without disrupting the laminarity of the continuous data.Type: GrantFiled: January 19, 1998Date of Patent: August 7, 2001Assignee: Physical Optics CorporationInventors: Allen Panahi, Freddie Lin, Tomasz P. Jannson
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Patent number: 6267562Abstract: At the suction side of a variable displacement compressor a valve structure is provided which either responds to a relative differential pressure value or a relative pressure value or a relative temperature value of the refrigerant processed by the variable displacement compressor such that in case of small load and a minimum operation state of the compressor the suction side will be cut-off or in case of large load and simultaneous minimum operation state of the compressor will not be cut-off. The valve structure automatically decides and responds to parameter changes representing in case of the minimum operation state of the compressor a large load or a small load, in order to avoid freezing of the fins of the evaporator in case of small load and to improve the fuel efficiency of the engine driving the compressor in case of large load.Type: GrantFiled: October 4, 1999Date of Patent: July 31, 2001Assignee: TGK Co., Ltd.Inventor: Hisatoshi Hirota
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Patent number: 6266476Abstract: A monolithic element has a substrate body and at least one macro-optical characteristic integral in a first portion of the optical element. A plurality of surface micro-structures are integral in a portion of the optical element. The micro-structures are designed to homogenize light passing through the optical element to produce a predetermined pattern of smoothly varying, non-discontinuous light exiting the optical element. The light exiting the optical element is therefore altered according to both the macro-optical characteristic of the optical element as well as the homogenizing characteristics of the micro-structures.Type: GrantFiled: August 25, 1998Date of Patent: July 24, 2001Assignee: Physical Optics CorporationInventors: Rick L. Shie, Jeffrey A. Laine, Gajendra D. Savant, Tomasz P. Jannson
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Patent number: 6262140Abstract: Compositions for producing replicated optical components are disclosed. A composition for making a large scale submaster optical component includes a mixture having an acrylated aliphatic urethane oligomer/monomer blend and a tripropylene glycol diacrylate. The mixture is combined with a number of other components including an isobornyl acrylate, an ultraviolet polymerizing varnish, a surfactant, and a photoinitiator. A composition for making a large scale replica optical component includes a mixture having an acrylated aliphatic urethane oligomer/monomer blend and a tripropylene glycol diacrylate. The mixture is combined with an isobornyl acrylate, a &bgr;-Carboxyethyl acrylate, a photoinitiator, and an N-vinyl-2-pyrrolidone. A composition for making a small scale submaster optical component includes an ultraviolet polymarizing varnish and a surfactant.Type: GrantFiled: July 13, 1999Date of Patent: July 17, 2001Assignee: Physical Optics CorporationInventors: Gajendra Savant, Hagop Latchinian
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Patent number: 6259562Abstract: A device has a carrier and an optical element supported by the carrier. The optical element has a macro-optical characteristic and at least one surface. A light shaping surface microstructure is integral on the surface of the optical element. The microstructure homogenizes, shapes and controls directionality of light emanating from the surface of the optical element to produce a smooth, consistent and continuous pattern of light in a predetermined distribution shape and direction. The optical element can either transmit or reflect light incident on a portion of the device and the optical element.Type: GrantFiled: August 25, 1998Date of Patent: July 10, 2001Assignee: Physical Optics CorporationInventors: Rick L. Shie, Jeffrey A. Laine, Gajendra D. Savant
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Patent number: 6256447Abstract: A backlight apparatus has a collimating waveguide with a light input end, a top surface, a bottom surface, opposing sides, a far end opposite the light input end, and a total internal reflection critical angle for the material of the waveguide. A plurality of first facets are formed in the bottom surface distributed along the waveguide between the light input end and the far end. Each of the first facets has a first facet bottom surface which converges toward the top surface in a direction away from the far end relative to the top surface. A light scattering and reflective surface is disposed adjacent the far end of the collimating waveguide. The first facet bottom surfaces cause light rays entering the light input end to be totally internally reflected to the far end of the collimating waveguide wherein the scattering and reflective surface at the far end reflects and scatters light rays incident thereon back toward the light input end.Type: GrantFiled: December 31, 1998Date of Patent: July 3, 2001Assignee: Physical Optics CorporationInventor: Jeffrey A. Laine
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Patent number: 6244477Abstract: A device for discharging concrete having a flexible hose which is connected to a concrete supply line, preferably a concrete supply line of a concrete pump, the hose is provided with an input end which is associated with the supply line and through which the concrete conveyed through the supply line enters the hose and an output end through which the concrete conveyed through the hose leaves the hose for the purpose of discharge. The hose is adapted to be bent in at least one swiveling plane between a substantially straight initial position and a curved position, and also has a swivel for moving the hose from its straight initial position to its curved position.Type: GrantFiled: April 9, 1999Date of Patent: June 12, 2001Inventor: Gerhard Hudelmaier
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Patent number: 6246052Abstract: A flexure carriage assembly has a carriage formed of a substantially rigid material. The carriage has four elongate columns arranged spaced apart and parallel to one another. Each of the elongate columns has first and second ends. The flexure carriage has four first cross members disposed between adjacent pairs of elongate columns and arranged to interconnect the first ends. The flexure carriage also includes four second cross members arranged between adjacent pairs of elongate columns and arranged to interconnect the bottom ends. The elongate columns and first and second cross members define a three-dimensional rectangular structure. The flexure carriage also has disposed centrally between the four elongate columns a translating section spaced equidistant between the first and second ends of the columns.Type: GrantFiled: September 20, 1999Date of Patent: June 12, 2001Assignee: Veeco Instruments, Inc.Inventors: Jason P. Cleveland, David Grigg
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Patent number: 6241903Abstract: A diffuser master is provided which is manufactured mechanically instead of holographically. The master can be made from a suitable substrate including relatively hard materials such as plastic, glass or metal. A substrate having a first side is worked to form a diffuser surface relief structure thereon. The substrate can be buffed using a buffing agent of a selected grit in order to form surface scratches in the first side of the substrate. The substrate can also be blasted with shot particles in order to form indentations and depressions in the first side. The substrate can alternatively be acid or alkali etched in order to form surface irregularities in the first side. The scratches, depressions or irregularities can be formed in order to create a desired surface relief and hence desired diffuser output characteristics.Type: GrantFiled: August 20, 1998Date of Patent: June 5, 2001Assignee: Physical Optics CorporationInventors: Gajendra D. Savant, Kevin H. Yu, Andrew A. Kostrzewski
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Patent number: 6234656Abstract: A fiber optic luminaire is arranged to couple light energy from a light source along its length. The fiber optic luminaire includes a plurality of light redirecting structures distributed along its length; the light redirecting structures are arranged to uniformly distribute by reflection light energy from the fiber optic luminaire. The light redirecting structures are preferably non-scattering structures, including structures such as microprisms, microfacets, microgrooves and micrometers. The fiber optic luminaire may be configured to a variety of shapes and to provide customized light distribution patterns.Type: GrantFiled: August 20, 1998Date of Patent: May 22, 2001Assignee: Physical Optics CorporationInventors: Abbas Hosseini, Tomasz P. Jannson, Stephen A. Kupiec, Anatoly Vasiliev
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Patent number: 6228909Abstract: Systems and methods for combining a mineral acid and a polymer additive in an asphalt composition are described. Methods of preparing a polymer modified asphalt include providing a source of a neat asphalt; heating the neat asphalt; providing a source of a polymer; adding the polymer to the neat asphalt to form a blend; providing a source of a dilution asphalt; and adding the blend to the dilution asphalt to form a diluted product. The systems and methods provide advantages in that the addition of the mineral acid widens the temperature range in which satisfactory performance from a given polymer asphalt composition can be achieved or, as a corollary, reduces the amount of polymer additive that would otherwise be needed to achieve satisfactory performance within a given temperature range.Type: GrantFiled: December 30, 1999Date of Patent: May 8, 2001Assignee: Ergon, IncorporatedInventors: Gaylon L. Baumgardner, Martin R. Burrow
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Patent number: 6226296Abstract: Systems and methods for connecting and configuring a communication network are described. A network includes a first router; a tie-line having a plurality of full duplex dedicated router interconnects connected to said first router; a second router connected to said plurality of full duplex dedicated router interconnects; a first user connected to said first router with a first full duplex loop; and a second user connected to said second router with a second full duplex loop. The systems and methods provide advantages in that bursty control information can be multiplexed with time sensitive laminar data.Type: GrantFiled: May 21, 1997Date of Patent: May 1, 2001Assignee: Physical Optics CorporationInventors: Lonnie Lindsey, Allen Panahi, Tomasz P. Jannson
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Patent number: 6216100Abstract: A method for the simulation of responses of a nonlinear amplifier provides for measuring characteristics of nonlinearity of amplitude and of amplitude/phase-shift conversion of the amplifier, each measurement being made at an amplitude that is constant in input. The method further includes measuring the characteristics at different frequencies, developing the characteristics in sequences of direct transfer functions, computing frequency correctors for the direct transfer functions, measuring characteristics of distortion of amplitude modulation, each measurement being performed by modulating the input amplitude, computing modulation transfer functions reproducing the distortion amplitudes at output according to the input modulation amplitudes and correcting the direct transfer functions when the input amplitude is modulated in order to simulate the envelope memory effect. There is a direct application of the invention to the field of the simulation of high efficiency microwave amplification.Type: GrantFiled: July 29, 1998Date of Patent: April 10, 2001Assignee: France Telecom SAInventors: Vahid Meghdadi, Jean-Pierre Cances, François-René Chevallier, Jean-Michel Dumas
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Patent number: 6206317Abstract: An apparatus for coiling a fire hose includes a base and a main support extending generally vertically and having upper and lower opposed ends, the lower end being attached to the base. The upper end includes a hose reel having an axle that is rotatably mounted to the upper end and which has an axle distal end. A crank is coupled to the axle of the hose reel to rotate the hose reel as the crank is correspondingly rotated. The crank has first and second opposed ends, the first end being releasably coupled to the axle distal end and the second end being configured to be gripped by a user. Next, the apparatus includes a retainer for coupling the fire hose to the hose reel, retainer including a handle and a pair of elongated rods that are spaced. To operate the apparatus, a portion of the fire hose near the male hose end is positioned between the elongated rods of the retainer, and then the retainer is coupled to the hose reel.Type: GrantFiled: April 23, 1999Date of Patent: March 27, 2001Assignee: Lake Area Fire Equipment Company, Inc.Inventor: Ronold L. Harvestine
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Patent number: 6208776Abstract: A sensor system comprises a broadband light source, a birefringent sensor, a detection circuit, and a signal processing unit. The preferred detection circuit further includes a variable frequency oscillator, a modulator, and a photodetector. The modulator modulates the output of the birefringent sensor with a modulation signal from the variable frequency oscillator. The modulation produces an interference signal having a variable interference frequency. By determining the frequency of the modulation signal from the variable frequency oscillator that minimizes the interference frequency, the detection system is able to determine the difference in frequency between first and second spectral components of the output of birefringent sensor. The detector may be constructed using entirely solid state optics/electronics. The preferred fiber grating sensor comprises a birefringent optical fiber having a cladding and a core.Type: GrantFiled: April 8, 1998Date of Patent: March 27, 2001Assignee: Physical Optics CorporationInventors: John D. Prohaska, Lothar U. Kempen, Robert A. Lieberman
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Patent number: 6201915Abstract: A remote light source lighting system is provided having an illuminator assembly including a housing. Held within the housing is a high intensity light source for providing light energy to a fiber optic cable bundle connected to the housing and facing the light source. The cable bundle includes a plurality of plastic optical fibers wherein at least one of the terminal ends of the bundle is formed by molding an optical quality resin around an optically transparent ferrule that binds the exposed ends of the optical fibers. The housing further includes a separate air plenum containing a blower. The blower produces a high velocity air stream directed precisely at the terminal end of the cable adjacent the light source to cool the terminal end.Type: GrantFiled: October 13, 1998Date of Patent: March 13, 2001Assignee: Physical Optics CorporationInventors: Alexander Rizkin, Yevgeniy Durets, Vladimir Rubtsov, David Ruiz, Robert H. Tudhope
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Patent number: 6201912Abstract: A sensor system comprises a broadband light source, a birefringent sensor, a detection circuit, and a signal processing unit. The preferred detection circuit further includes a variable frequency oscillator, a modulator, and a photodetector. The modulator modulates the output of the birefringent sensor with a modulation signal from the variable frequency oscillator. The modulation produces an interference signal having a variable interference frequency. By determining the frequency of the modulation signal from the variable frequency oscillator that minimizes the interference frequency, the detection system is able to determine the difference in frequency between first and second spectral components of the output of birefringent sensor. The detector may be constructed using entirely solid state optics/electronics. The preferred fiber grating sensor comprises a birefringent optical fiber having a cladding and a core.Type: GrantFiled: November 5, 1999Date of Patent: March 13, 2001Assignee: Physical Optics CorporationInventors: Lothar U. Kempen, John D. Prohaska, Robert A. Lieberman
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Patent number: 6196061Abstract: Thermal drift and acoustic vibrations in the AFM are reduced using a probe-based detection device that references the topography measurement of the AFM to the sample surface in the proximity of the measurement probe. A differential measurement is made between the reference probe and the measurement probe for high sensitivity roughness quantification and defect detection. Multi-probe arrays may be used for large area defect detection with immunity from thermal and acoustic noise sources.Type: GrantFiled: November 5, 1998Date of Patent: March 6, 2001Assignee: Nanodevices, Inc.Inventors: Dennis M. Adderton, Stephen C. Minne
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Patent number: RE37214Abstract: A side dam assembly for a continuous casting apparatus for continuously casting thin steel strips between casting rolls. The side dam assembly has a side dam for bearing directly against the rolls of the casting apparatus for preventing leakage of molten metal therebetween. The side dam is attached by a pair of belts to an insulating refractory plate which is carried by a cooled panel. To allow axial motion, one of the belts is not rigidly affixed to either the insulating refractory plate or the side dam. The cooled panel is carried by a thrust plate and is urged toward the rolls by biasing elements which preferably comprise a plurality of pistons urged outwardly from the thrust plate by springs. Preferably, the biasing elements are constructed and arranged so that they are distributed over a zone of shape corresponding to that of the side dam and are capable of exerting on the side dam thrust forces independently of one another.Type: GrantFiled: December 17, 1998Date of Patent: June 12, 2001Assignees: Usinor, Thyssen Stahl AktiengesellschaftInventors: Jacques Barbé, Luc Vendeville, Pierre Delassus