Patents Represented by Attorney, Agent or Law Firm Omri M. Behr, Esq.
  • Patent number: 6043293
    Abstract: There are provided foamable, foamable polyvinyl halide resin masses containing: A) 1 to 25 parts relative to 100 parts of polyvinyl halide, of a polymerizate obtainable through the emulsion polymerization of i) up to 20 to not more than 75 parts of methylmethacrylate, ii) 25 to 80 parts of one or more C.sub.2 -C.sub.18 alkylmethacrylates, iii) 0 to 5 parts of one or more vinyl unsaturated monomers copolymerizable with (i) and/or (ii, wherein the components (i)-(iii) together yield 100 parts and are polymerized with up to a further 100 parts of usual additives for emulsion polymerization, wherein the emulsion polymerizate is single stepped and has a viscosity number of >700 cm.sup.3 /g and wherein copolymers are excluded which contain iv) MMA per se, or less than 20 or more than 75 parts of MMA together with either v) one or more acrylic acid esters, and/or vi) ethyl methacrylate, n-butyl-methacrylate, or ethylhexyl methacrylate. The resin mass further includes: B) 0.
    Type: Grant
    Filed: October 19, 1998
    Date of Patent: March 28, 2000
    Assignees: Agomer Gesellschaft mit beschrankter, Barlocher Gesellschaftmit beschrankter Hatfung
    Inventors: Pavel Belik, Georg Schneider, Klaus Dorn, Stefan Forster, Bernd Frischkemuth
  • Patent number: 6037474
    Abstract: The present invention relates to a process for the preparation of cyclic 4-oxoamidines. Such substances are precursors of active substances having biological action. The process according to the invention forms a further method of obtaining this class of compound.By reacting condensation products of aldehydes and aminonitriles or amino acid amides with oxidizing agents, the desired cyclic 4-oxoamidines are obtained according to the invention in good to very good yields.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: March 14, 2000
    Assignee: Degussa-Huuls
    Inventors: Karlheinz Drauz, Rolf Hoffmann, Ivan Pilgrims
  • Patent number: 6018050
    Abstract: The invention relates to a new process for the preparation of optically active amino acids and amino acid derivatives of the general formula (I), wherein *, X and R.sup.1 to R.sup.4 have the meaning given in the description. Starting from commercially obtainable (-)-menthol or (+)-menthol, the enantiomerically pure compounds of the formula (I) are obtained in high yields. The method is particularly suitable for the preparation of sterically demanding amino acids and amino acid derivatives.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: January 25, 2000
    Assignee: Degussa Aktiengesellschaft
    Inventors: Hans-Josef Altenbach, Matthias Kottenhahn, Annegret Vogt, Mike Matthaus, Andreas Grundler, Michael Hahn
  • Patent number: 6013033
    Abstract: Catheter for echographic imaging within a cavity, comprising a proximal end situated to the outside of the patient, a distal end situated close to the tissues which are to be investigated, and a body connecting these two ends, the distal end comprising a guide wire and a capsule which is transparent to ultrasound and in which are accommodated a fixed piezoelectric transducer and a mirror for deflecting the ultrasonic wave and driven by means of rotation accommodated in the said capsule, this catheter being characterized in that the said mirror (30) is placed directly, without torque transmission shaft, on the surface of the rotor (34) of a microactuator constituting the said means of rotation.
    Type: Grant
    Filed: August 31, 1998
    Date of Patent: January 11, 2000
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Genevieve Berger, Nicolas Bovo, Isabelle Dufour, Jean-Paul Grandchamp, Pascal Laugier, Charles Sol, Sylvain Allano
  • Patent number: 6009729
    Abstract: A process can form an arrangement for a warp knitting or circular knitting machine with (a) a single hardenable retaining material, (b) a plurality of thread processing elements having proximal ends, and (c) a carrier having a face with a groove. The process includes the step of introducing the hardenable retaining material before it is hardened into the groove of the carrier. The process also includes the step of holding the thread processing elements in a single plane. Another step is introducing the proximal ends of the thread processing elements into the non-hardened retaining material, keeping the thread processing elements in a single plane with even separation while protruding from the face of the carrier. The process also includes the step of waiting for hardening of said retaining material, wherein the proximal ends are embedded in the carrier.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: January 4, 2000
    Assignee: Karl Mayer Textilmachinenfabrik GmbH
    Inventor: Josef Halassek
  • Patent number: 6009661
    Abstract: A snake trap is disclosed in which a trigger activated door (4) closes in response to a horizontal force being applied to the trigger (7) which is pushed against by the snake as it moves within the trap.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: January 4, 2000
    Inventor: Graham R. Lloyd
  • Patent number: 5993687
    Abstract: An acrylonitrile solution of maleimide manifesting transparency, precluding coloration and opacification during the course of handling, and excelling in stability, a method for the preparation of the acrylonitrile solution, and an acrylonitrile based copolymer obtained by using the acrylonitrile solution are provided.The acrylonitrile solution of maleimide is such that, when it is subjected to a forced coloration test, the differences .DELTA.L, .DELTA.a, and .DELTA.b values (invariably as absolute values) each between L, a, and b values before and after the test are respectively not more than 5, not more than 5, and not more than 10. The acrylonitrile solution of maleimide is prepared by lowering the water content in the acrylonitrile solution to a level of not more than 0.
    Type: Grant
    Filed: August 27, 1996
    Date of Patent: November 30, 1999
    Assignee: Nippon Shokubai, Ltd.
    Inventors: Kazuo Kishino, Kinichi Nakayama, Fumioki Shimoyama, Yuichi Kita
  • Patent number: 5981804
    Abstract: A catalyst for the production of unsaturated aldehyde and unsaturated carboxylic acid by the vapor-phase catalytic oxidation of at least one compound selected from the group consisting of propylene, isobutylene, t-butanol and methyl-t-butyl ether and a method for the production of unsaturated aldehyde and unsaturated carboxylic acid by the use of this catalyst are provided. The catalyst of this invention comprises (A) a catalyst having Mo, Bi and Fe as essential components and used for the production of unsaturated aldehyde and unsaturated carboxylic acid by vapor-phase catalytic oxidation of propylene, isobutylene, t-butanol and/or methyl-t-butyl ether and (B) a solid acid having acid strength (Ho) of not more than -11.93. Since this catalyst excels in catalytic activity and service life, it allows unsaturated aldehyde and unsaturated carboxylic acid to be produced stably at a high yield for a long time.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: November 9, 1999
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Ikuo Kurimoto, Tatsuya Kawajiri, Hideo Onodera, Michio Tanimoto, Yukio Aoki
  • Patent number: 5976382
    Abstract: There is provided water insoluble cross-linked polycarboxylic acid having at least two strands in a strand skeleton of the formula: ##STR1## wherein one carbonyl group of at least one maleoyl moiety thereof in each strand is covalently linked to a--HN.[(H).sub.p (CH).sub.2.(OH).sub.m ].NH-- moietyto provide the presence therein of at least one cross linked moiety of the formula: ##STR2## wherein R is hydrogen or lower alkylene or lower alkoxy of 1-4 carbon atoms, or phenyl, x and y are integers, z is an integer of 1-6, p is 0 or an integer up to z-1, m is 0 or an integer up to z, and w is an integer from 2-12. There is disclosed a method of making such polycarboxylic acid as well as methods of utilizing same to remove proteins from aqueous media containing same to provide a matrix. Methods are disclosed for recovering proteins from said matrix without denaturing them and methods for recovering the polycarboxylic acid from said matrix.
    Type: Grant
    Filed: July 10, 1996
    Date of Patent: November 2, 1999
    Assignee: LigoChem, Inc.
    Inventor: John Krupey
  • Patent number: 5966969
    Abstract: A segment carrying knitting elements for a warp knitting machine comprising a plurality of similar plates. Holes provided in said plates are penetrated by at least one hollow pin, which at its circumference is connected with the plates. This gives rise to low weight segments for attachment to the bars of a warp knitting machine.
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: October 19, 1999
    Assignee: Karl Mayer Textilmachinenfabrik GmbH
    Inventor: Kresimir Mista
  • Patent number: 5962696
    Abstract: There is provided a process for the work-up of this material having the formula ##STR1## because of its poor crystallizability has heretofore been available only with large yield losses. The yield losses are due to the fact that the crystals of this compound are associated with large amounts of residual solvent material which gives rise to complex and expensive drying procedures. In accordance with the present invention the crude LPE is dried by means of fluid or supercritical carbon dioxide which maces it possible to reduce drying times from the previous range of about 124 hours to about 10 hours for the same amount of product and thus produce a dry LPE which has smaller amounts of residual solvent, as well as smaller by-products than that obtained by conventional drying.
    Type: Grant
    Filed: June 9, 1998
    Date of Patent: October 5, 1999
    Assignee: Degussa Aktiengesellschaft
    Inventors: Herbert Tanner, Karlheinz Drauz, Klaus Stingl, Gerhard Sator, Horst Bethge, Roland Moller, Thomas Tacke, Claus Rehren
  • Patent number: 5959124
    Abstract: A vanadium-phosphorus oxide having an X-ray diffraction spectrum (Cu--K.alpha.) showing main peaks of the diffraction angle 2.theta.(.+-.0.2.degree.) at 18.5.degree., 23.0.degree., 28.4.degree., 29.9.degree., and 43.1.degree. and having the intensity ratio of the peaks of the diffraction angle 2.theta.(.+-.0.2.degree.) at 23.0.degree. and 28.4.degree. in the following range0.3.ltoreq.I (23.0)/I (28.4).ltoreq.0.7wherein I (23.0) and I (28.4) respectively represent the intensities of the peaks of the diffraction angle 2.theta.(.+-.0.2.degree.) at 23.0.degree. and 28.4.degree., a method for the production of the oxide, a catalyst for use in a vapor phase oxidation formed of the oxide, and a method for the partial vapor phase oxidation of a hydrocarbon.
    Type: Grant
    Filed: March 31, 1997
    Date of Patent: September 28, 1999
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Hideto Hashiba, Akiyoshi Nakajima, Shinichi Higashi
  • Patent number: 5959147
    Abstract: This invention concerns a novel organic sulfide compound obtained by the reaction of a mercapto alkanol such as 2-mercapto ethanol with an unsaturated amide such as (meth)acrylamide, maleic acid diamide, or fumaric acid diamide and a method for the production of the organic sulfide compound. The invention enables novel organic sulfide compounds of great commercial utility to be obtained with a high yield on a commercial scale.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: September 28, 1999
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Norihiro Wakao, Youichi Hino, Ryuichi Ishikawa
  • Patent number: 5955098
    Abstract: A buccal aerosol spray or capsule using a non-polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprises formulation I: propellant 50-95%, non-polar solvent 5-50%, active compound 0.001-15%, flavoring agent 00.05-5%. The soft bite gelatin capsule of the invention comprises formulation II: non-polar solvent 55-99.8%, emulsifier 0-20%, active compound 0.001-25%, and flavoring agent 0.05-5.0%.
    Type: Grant
    Filed: April 12, 1996
    Date of Patent: September 21, 1999
    Assignee: Flemington Pharmaceutical Corp.
    Inventor: Harry A. Dugger, III
  • Patent number: 5951909
    Abstract: There is provided a method for the detection of leaks of an electrophilic gas from a system, such as chlorodifluoromethane or carbon dioxide, which comprises applying to an exterior surface of the system a gel consisting essentially of a Lewis base capable of removing a proton from the gas or reacting therewith in a similar electrophilic manner; a dye capable of visibly indicating a color change on protonation or deprotonation; a solvent for the dye, the base and the gas; and a rheology modifier capable of producing a non-newtonian gel of all of these components which is sufficiently translucent to permit visual detection of change of color of the dye and of sufficient pseudoplasticity/thixotropy to provide adhesion to vertical and horizontal surfaces.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: September 14, 1999
    Assignee: R-Tec Technologies, Inc.
    Inventors: Robert J. Verdicchio, Stewart R. Kaiser, Shawn Walsh
  • Patent number: 5942218
    Abstract: The subject matter comprises anti-infective materials such as antimicrobial materials based upon poly(hexamethylene)biguanide having a weight proportion of said polymer containing 5 or less units per chain is less than 2% based on entire polymer weight, which are suitably in the form of a wound antiseptic and/or a wound treating material or a material for anti-microbial, antiviral, and/or antiparasitic treatment which may suitably be administered by the intravenous mode. The utilization concentration of the poly(hexamethylene)biguanide as a wound antiseptic and/or a wound treatment material suitably lies in the range of 0.001 through 0.05 wt. %, in particular 0.005 through 0.012 wt. %.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: August 24, 1999
    Assignee: Fresenius AG
    Inventors: Ulrich Kirschner, Frank Jethon, Frank Rauch
  • Patent number: 5942489
    Abstract: A peptide selected from the group having the formulae:.alpha.) X-R.sup.1 -R.sup.2 -R.sup.3 -R.sup.4 -R.sup.5 -R.sup.6 -Thr-R.sup.8 -R.sup.9 -R.sup.10 -R.sup.11 -R.sup.12 -Val-Leu-R.sup.15 -Gln-Leu-Ser-R.sup.19 -R.sup.20 -R.sup.21 -Leu-Leu-Gln-Asp-Ile-R.sup.27 -R.sup.28 -R.sup.29, wherein X is H, Ac, Aqc, IAc, BrProp, For, Ibu, Nac, 2-Nac, 1- or 2-Npt, 1- or 2-Npr, PhAc, Fpr, or any other aromatic or nonpolar acyl group, R.sup.1 is Tyr, His or Phe(Y), in which Y=H, F, Cl, Br, NO.sub.2, CH.sub.3 or OCH.sub.3, R.sup.2 is D-Arg, D-Cit, D-Har, D-Lys, D-Tic or D-Orn, R.sup.3 is Asp, D-Asp, Ala, D-Ala or Gly, R.sup.4 is Ala, Abu or Gly, R.sup.5 is Ile, Ala or Gly, R.sup.6 is Phe, Tic, Ala, Pro, Tpi, Nal or Phe(Y), in which Y=H, F, Cl, Br, NO.sub.2, NH.sub.2, CH.sub.3 or OCH.sub.3, R.sup.8 is Asn, Gln, Ser, Thr, Val, Leu, Ile, Ala, D-Ala, D-Asn, D-Gln, D-Thr, D-Leu, Abu, D-Abu, Nle, or Alb, R.sup.9 is Ser, R.sup.10 is Tyr or Phe(Y), in which Y=H, F, Cl, Br, NO.sub.2, CH.sub.3 or OCH.sub.3, R.sup.
    Type: Grant
    Filed: May 3, 1996
    Date of Patent: August 24, 1999
    Assignee: The Administrators of the Tulane Educational Fund
    Inventors: Andrew V. Schally, Marta Zarandi, Katalin Toth
  • Patent number: 5932758
    Abstract: Disclosed is a process for producing .beta.-amino-.alpha.-hydroxycarboxylic acid derivatives of general formula (2R,3S)- or (2S,3E)-N-(X,Y)-3-amino-2-hydroxy-3-phenyl propionic acid-Z of Formula I, ##STR1## e.g. of (2E,3S)-3-amino-2-hydroxy-3-phenyl propionic acid or (2R,3S)-N-benzoyl-3-amino-2-hydroxy-3-phenyl propionic acid methylester. Compounds of type I are valuable intermediates in the total synthesis of Taxols which can be used in the treatment of various forms of cancer.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: August 3, 1999
    Assignee: Degussa Aktiengesellschaft
    Inventors: Klaus Stingl, Matthias Kottenhahn, Karlheinz Drauz
  • Patent number: 5929139
    Abstract: A method for the recovery of microfine suspended particles from a suspension medium, characterized by subjecting a polymeric monomer suspended in a suspension medium to suspension polymerization thereby forming microfine globular particles in the suspension solution, adding microfine water-insoluble particles to said suspension solution of microfine globular particles thereby inducing cohesion of said microfine globular particles, and separating said microfine globular particles in the form of an aggregate from said suspension solution filtration.
    Type: Grant
    Filed: October 8, 1997
    Date of Patent: July 27, 1999
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Yoshikuni Mori, Mitsuo Kushino, Hideki Oishi, Tadahiro Yoneda
  • Patent number: D422853
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: April 18, 2000
    Inventor: Martha Frimer Cheslow