Abstract: Novel growth hormone releasing factor analogs in which glycine at position 15 is replaced by appropriately selected amino acids demonstrate enhanced potency for the release of growth hormone and the analogs can be administered to a subject having a deficiency of growth hormone.
Type:
Grant
Filed:
September 24, 1984
Date of Patent:
November 11, 1986
Assignee:
Hoffmann-La Roche Inc.
Inventors:
Arthur M. Felix, Edgar P. Heimer, Thomas F. Mowles