Abstract: A method for improving the radial enlargeability and other properties of tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. Broadly, the method comprises the step of radially shrinking the reinforcement tape layer of the graft, or the entire tape-reinforced graft, after sintering thereof. Such radial shrinkage of the reinforcement tape layer, or of the entire graft, renders the graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel.

Abstract: A catheter-based material removal device includes an elongated tube having a distal material removal tip thereon. The material removal tip includes a one- or two-piece housing affixed to the tube, and a rotating member therein. The rotating member includes a screw thread for coarsely chopping material received within the housing and an outwardly projecting flange for finely chopping the material. The housing includes at least one shearing member located axially adjacent the outwardly projecting flange. The shearing member has a relatively small circumferential size and a shearing edge that removes any material buildup on the axially-facing surface of the flange. Two shearing members may be provided, one each on both the proximal and distal sides of the flange. There may be three flanges restrained within a groove formed with the housing.

Abstract: An intraluminal catheter for directing a guidewire and/or catheter in a desired direction within a bodily vessel or cavity. The intraluminal catheter has a first elongate tubular member and a support means which can comprise a second elongate tubular member that can pass over a main support guidewire. The catheter acts as a platform as the guidewire is passed through the first elongate tubular member and is deflected transversely outwardly by an angled surface through an aperture. A second intraluminal catheter has a first elongate tubular member and a support means comprising a second elongate tubular member. The first elongate tubular member has a main portion and an end portion, with the end portion being deflectable relative to the locus of the main portion so as to direct the guidewire passing through the end portion in a desired direction in the bodily vessel.

Abstract: Methods for utilizing a device for blocking (e.g., embolizing) the side branches of an anatomical passageway under endoscopic guidance. The device comprises an elongate catheter body having a side branch blocking apparatus, such as an embolization catheter, disposed therein and further incorporating an endoscope (e.g., an angioscope). The incorporated endoscope is useable to a) visually locate side branches which emanate from the anatomical passageway and b) visually observe the operation of the side branch blocking apparatus. Disclosed are methods for performing in situ embolization of the side branches of a vein, under angioscopic visualization. The endoscopic component of the device may also be utilized to visually observe the use and/or effect of one or more separate device, such as valvulotome(s) used for cutting venous valves located within the lumen of a vein.

Abstract: Methods for folding a catheter mounted balloon, and delivery catheter systems which incorporate radially expandable intraluminal devices (e.g., stents, grafts and stented grafts) which are mounted on a balloon folded in accordance with this method. The method comprises generally folding the balloon at least twice, in opposite directions, so that any rotational forces created by the unfolding of the balloon as it is inflated will counteract each other, and will thus avoid substantial rotational movement of the intraluminal device during its radial expansion.

Abstract: A smooth-walled non-crimped inflow conduit for an implantable ventricular assist system. The conduit has an internally smooth lumen surface for enhanced washing of the conduit under irregular blood flow conditions. The conduit includes a tubular graft body that may be formed of a knitted fabric sealed with bovine collagen or gelatin, or formed of closed structured PTFE. The conduit may include external ribbing or support to prevent inward collapse under negative pressure conditions and also protect against damage from inadvertent physical contact in the operating room. The external support may be bonded to the exterior or formed integrally with the tubular graft body. An outer reinforcement cage may be provided to help prevent gross distortion or damage to the tubular graft body. The ends of the tubular graft body are left unsupported and wrapped around opposed lips of conduit coupling structure to minimize blood contacting surfaces at junctions with other conduits or with the heart.

Abstract: An externally supported, tape-reinforced tubular prosthetic graft and method of manufacturing therefore. The graft comprises a tubular base graft formed of expanded, sintered fluoropolymer material, a strip of reinforcement tape helically wrapped about the outer surface of the tubular base graft and attached thereto, and, an external support member helically wrapped around the outer surface of the reinforcement tape and attached thereto. The helical pitch of the reinforcement tape is different from the helical pitch of the external support member. Preferably, the helical pitch of the reinforcement tape is in a direction which is opposite the direction of the external support member.

Abstract: A process for producing a surfboard having rails encapsulated with a tight woven band of fabric providing up to sixty percent improvement in strength over conventional fiberglass constructions is disclosed. A product produced by said process is also taught, which allows extreme surfers to push the performance envelope and attack bigger waves, among other things.

Abstract: The body of a rail vehicle is lowered when it is stationary to facilitate ingress and egress. The body is raised in preparation for motion to provide satisfactory road clearance. In one embodiment of the invention, a lifting cylinder, in series with a supplementary spring, is extended during travel, and is contracted when the rail vehicle is stopped. In other embodiments, a hydraulic cylinder, either alongside, or coaxial with the supplementary spring, compresses the supplementary spring when the rail vehicle is stopped. In a further embodiment, the hydraulic cylinder is replaced with an electromechanical adjusting element such as a screw drive. A control system, preferably actuated by unlocking and locking of the door opening lock, actuates the lowering and raising of the body.

Abstract: A camera with a data imprinting device has a plurality of in-line LEDs producing light focused by an optical system upon a photographic film at a first and a second position, corresponding to a full size format and a panorama size format, respectively. The focused light imprints data images upon the film at the first position are larger than data images imprinted at the second position. The optical system has first and second prisms, with integrated lenses, for reflecting and focusing the light upon the film at the first and second positions, respectively. A shutter plate is selectively positioned over apertures through which the light is focused, thus blocking the light and allowing only a selected imprint to be made upon the film. A vertical pattern of the data image is created by a controller selectively illuminating the in-line LEDs while a horizontal pattern is produced by the controller illuminating the LEDs in coordination with the movement of the film past the apertures.

Abstract: A therapeutic agent for allergic diseases containing as an active ingredient an extract of Acanthopanax senticosus Harms. It became possible to provide a medicine enabling allergic diseases to be treated without causing almost no side effects.

Abstract: A cell analyzing system flows a liquid to be tested and a sheath liquid through a flattened flow passage. An image of the flattened flow passage is formed at two different magnifications. The thickness of the liquid to be tested in the flattened flow passage is changed between the two different magnifications to maintain this thickness at a value smaller than a depth of field of the apparatus forming the image. The thickness of the liquid to be tested is changed by changing its flow relationship to the sheath liquid.