Abstract: A programmable memory is provided in each of a plurality of detector modules arrayed in a positron emission tomography (PET) scanner. Each detector module memory stores data associated with its respective detector module. Each memory may be coupled to a processor via a transmission bus. A display device may be coupled to the processor for displaying information relating to information obtained from the detector module memories.

Abstract: A shield for absorbing radiation emitted during generation of a radioisotope. The shield includes an inner portion fabricated from a first type of shielding material. The shield also includes an outer portion fabricated from a second type of shielding material wherein the outer portion serves as a mold for forming the inner portion. The inner portion may be fabricated from a material which shields against gamma rays such as concrete. The outer portion may be fabricated from a material which moderates neutrons such as high density polyethylene. Additional shielding materials may be embedded into the inner portion as desired.

Abstract: An imaging system includes interleaved emission detectors and transmission detectors. Emission detectors and transmission detectors can be interleaved along the axis of relative patient motion. Emission detectors and transmission detectors can be interleaved orthogonal to the axis of relative patient motion. Emission detectors can be single photon emission computed tomography detectors and the transmission detectors can be x-ray computed tomography detectors.

Abstract: An event data transmission scheme is provided for reducing positron emission tomography event losses. The event data transmission scheme employs a more effective use of available data bandwidth. Each of a plurality of detector data slots is connected directly to a data aggregation control interface, and the control interface is connected to a coincidence processor.

Abstract: A method for processing events in a medical imaging device may comprise the steps of receiving analog signals from at least one PMT into an Applied Specific Integrated Circuit (ASIC) comprising a Constant Fraction Discriminator (CFD) and transmitting analog outputs from the ASIC. Further, sampling the analog outputs continuously using an Analog to Digital Converter (ADC) and transmitting digital outputs; and collecting a number of samples of the digital output during a sampling period using a Field Programmable Gate Array (FPGA) when triggered by the CFD. The method may additionally determine the energy of the analog signals from the at lease one PMT by subtracting the peak value of each signal from the baseline value of each signal, wherein the peak value is determined as an average of at least one sample taken only around the peak during the sampling period, and the baseline value is determined as an average of at least one sample taken only around the beginning or end of the sampling period.

Abstract: A method for measuring a SPECT collimator's hole orientation angles includes (a) providing a plurality of parallel spaced apart line radiation sources at a distance from a detector; (b) positioning a first collimator between the plurality of spaced apart line radiation sources and the detector; (c) obtaining a set of line images of the plurality of line radiation sources by scanning/stepping the plurality of line radiation sources across the first collimator in a first direction; (d) obtaining a second set of line images of the plurality of line radiation sources by scanning/stepping the plurality of line radiation sources across the first collimator in a second direction thai is perpendicular to the first direction; (c) repeating the steps (c) and (d) for a second collimator, wherein one of the two collimators is a reference collimator and the other of the two collimators is a collimator being measured.

Abstract: A system and method for smoothing digital images using a non-orthogonal convolution kernel involves steps for rearranging and remapping input image data and the convolution kernel image from hexagonal coordinate mapping to orthogonal mapping of a memory space thus enabling implementation of a general box filter convolution strategy to smooth the input image.

Abstract: A method for performing direct rendering of a multi-volume data, having the steps of determining whether a volume of the multi-volume data is one of active and inactive via interaction with a ray for the multi-volume data, recording in triplicate a starting point and an end point of the ray for an eyespace, repeating the determining whether the volume is one of active and inactive via interaction with a ray for the multi-volume data and the recording in triplicate a starting point and an end point of the ray for an eyespace for all volumes of the multi-volume data, providing triples from all volumes to an array, sorting the array to create a sorted triples list array, breaking the ray into a plurality of segments using the sorted triples list array, determining which volumes are active for each of the segments via an active volume list, and sampling each segment of the ray to acquire an accumulated result.

Abstract: A method for improving timing response in light-sharing scintillation detectors is disclosed. The method includes detecting an event, by a plurality of photo sensors, from a scintillation crystal. The method then includes sampling and digitizing the photo sensor outputs by an analog-to-digital converter. Then the method includes correcting associated timing data, by a processor, for each of the photo sensor outputs based on a lookup table. The method then includes selectively time shifting the photo sensor outputs based on the lookup table to generate corrected photo sensor outputs. The method then includes summing the corrected photo sensor outputs by the processor. The method then includes generating an event time, by the processor, for the detected event based on the sum of the corrected photo sensor outputs.

Abstract: A patient bed drive mechanism, under control of a processor, is capable of continuously moving a patient bed through the a TOF-PET detector array having a stationary field of view (FOV) for a distance in excess of the physical extent of an axis of the array FOV. A direct memory access (DMA) rebinner card is coupled to the detector array to receive therefrom a stream of TOF-PET coincidence event data during the extent of movement of the bed. Image projection data are generated in real time from the acquired stream of TOF-PET coincidence event data via the DMA card.

Abstract: A method for measuring a SPECT collimator's hole orientation angles includes obtaining a set of stepped radiation line images of a line radiation source by scanning/stepping the line radiation source across a first collimator in a first direction; obtaining a second set of stepped radiation line images of the line radiation source across the first collimator in a second direction that is perpendicular to the first direction; and obtaining two sets of stepped radiation line images for a second collimator, wherein one of the two collimators is a reference collimator and the other is a collimator being measured. Calculating the collimator hole orientation angles requires determining offset distances along the two directions for each pair of lines between the reference collimator's line images and the measured collimator's line images by identifying and pairing the lines from the reference collimator line images and the measured collimator line images.

Abstract: A system and methods for volume rendering using n-pass sampling are disclosed. A plurality of first rays in a first density is sampled through a volume. Each of the first rays is in a separate section. A value of at least one first ray is compared to a first threshold. A plurality of second rays in a second density is sampled based on the comparison of the at least one first ray. The second rays are in a first section of the separate sections. The first section being for the at least one first ray. A value of at least one second ray is compared to a second threshold. A plurality of third rays is sampled in a second section spatially different than the first section based on the comparison of the at least one second ray. An image rendered from the sampling of at least the first rays is displayed.

Abstract: A method for tomographic nuclear imaging determines the distance between a non-parallel hole collimator surface and a region of interest (ROI) by obtaining difference images between images acquired at different view angles of the ROI. The distance may be used in a nuclear image reconstruction algorithm to more accurately reconstruct an image of the ROI. The method takes advantage of the non-stationary Point Spread Function of a non-parallel hole collimator to determine depth information of gamma events emitted from the ROI.

Abstract: A grid computing system and method is provided for medical data processing. The grid computing system comprises a software infrastructure, and an imaging device capable of interfacing with the software infrastructure over a distributed electronic network. Also included is a plurality of CPUs capable of interfacing with the software infrastructure over the network. The performance of the plurality of CPUs is dependent on balancing load. A large medical dataset is split onto several processing nodes of the plurality of CPUs, respectively, such that performance and power is increased. In the grid computing method, a grid is limited to a nuclear medicine or radiology network. A tight and easy configuration management of computing nodes, and a tight load balancing between standardized nodes are provided. An existing network of CPUs is utilized, such that the greatest benefit is provided at the lowest cost.

Abstract: LSO scintillation crystals with improved scintillation and optical properties are achieved by controlled co-doping a LSO crystal melt with amounts of cerium and an additional codopant such as calcium or other divalent cations. Crystal growth atmosphere is optimized by controlling the amount of oxygen in the atmosphere. Zinc is added as an additional material to restabilize crystal growth where calcium co-dopant is added. The decay time of the scintillation crystal can be controlled by controlling the concentration of co-dopant added.

Abstract: Estimating time-of-flight (TOF) scatter distribution in a positron emission tomography (PET) system. Obtaining PET TOF projection data: PET random coincidence data and PET TOF prompt coincidence events data. Reducing measured TOF projection data to non-TOF projection data. Reconstructing, unbiased, the non-TOF projection date. Forward projecting unbiased reconstructed non-TOF projection data to estimate TOF trues distribution. Subtracting: The estimated TOF trues distribution and the measured random coincidence, from measured TOF prompt coincidence events.

Abstract: The present invention is a photodetector including improved photosensors configured of an array of small (sub-millimeter) high-density avalanche photodiode cells utilized to readout a single scintillator. Each photosensor comprises a plurality of avalanche photodiodes cells arranged in an (n×n) array of avalanche photodiode cells (where, n>1) that are coupled to a single scintillation crystal. The overall (n×n) array area as the photosensor is the same as the area of a face of the scintillator and each avalanche photodiode cell has a surface area that is not greater than one square millimeter. The photosensor is also configured to facilitate reading the output of each avalanche photodiode cell in the array. By reading out each small avalanche photodiode cell independently, the noise and capacitance are minimized and thereby provide a more accurate determination of energy and timing.

Abstract: An optical mask positioned on a scintillator array. The optical mask includes a reflective layer. One or more windows can be positioned on the surface of optical mask.

Abstract: Providing information representative of an image in an interactive visualization system includes selecting a current image from a stream of images, evaluating context information within the visualization system, and determining representative information for the current image on the basis of the context information.

Abstract: A computer-implemented method of presenting an image of an object includes causing a computer to execute instructions for providing a signal distribution of values N, generating a transformed distribution by calculating, for each value N, a transformed value X=?{square root over (N+?)}, and outputting the transformed distribution.