Patents Represented by Attorney, Agent or Law Firm Pharmaceutical Patent Attys, LLC
  • Arginine derivatives with NP-1 antagonistic activity
    Patent number: 8227606
    Abstract: The present invention is a compound of formula (I) or formula (II) which are suitable as NP-1 antagonists.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: July 24, 2012
    Assignee: Ark Therapeutics, Ltd.
    Inventors: Haiyan Jia, Ian Zachary, Michelle Tickner, Lili Cheng, Chris Chapman, Katie Ellard, Basil Hartzoulakis, Ashley Jarvis, Rosemary Lynch, Jamie Nally, David Selwood, Mark Stewart
  • Solid phase Fmoc chemistry process to prepare peptides
    Patent number: 7897724
    Abstract: The present invention relates to an improved process for the preparation of N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-?-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1?6)-disulfide of formula (1), which involves assembling a peptide chain comprising of six amino acids and a thioalkyl carboxylic acid in a required sequence on a solid support to obtain a peptide bound resin of formula (2), capping the free amino groups after each coupling, cleaving Dde group in the peptide of formula (2) from the solid support to obtain peptide-solid support of formula (3), guanylating the peptide of formula (3) at ?-lysine-NH2 in an organic solvent to obtain peptide-solid support of formula (4), cleaving and deprotecting all groups in the peptide of formula (4) from the solid support to obtain peptide-amide formula (5), oxidizing the SH-peptide of formula (5) with an appropriate oxidizing agent to obtain the crude peptide-amide of formula (1) and purifying the crude peptide-amide of formula (1)
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: March 1, 2011
    Assignee: USV, Ltd.
    Inventors: Divya Lal Saksena, Shrikant Mishra, Chandrakesan Muralidharan, Nilesh Patil, Nikhil Umesh Mohe, Mandar Ravindra Maduskar
  • Process for the preparation of sevelamer hydrochloride and formulation thereof
    Patent number: 7846425
    Abstract: Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: December 7, 2010
    Assignee: USV, Ltd.
    Inventors: Deepak Anant Hegde, Varsha Shashank Choudhary, Yogesh Sharad Bhide
  • Process for preparation of 4-amino-1-isobutyl-1H-imidazo[4,5-C]-quinoline (Imiquimod)
    Patent number: 7678912
    Abstract: A process for preparation of 1-isobutyl-1H-imidazo-[4,5-c]-quinoline-5-N-oxide, comprising oxidation of 1-isobutyl-1H-imidazoquinoline with meta-chloroperbenzoic acid.
    Type: Grant
    Filed: December 27, 2004
    Date of Patent: March 16, 2010
    Assignee: USV, Ltd.
    Inventors: Venkatasubramanian Radhakrishnan Tarur, Suresh Mahadev Kadam, Anil Purushottam Joshi, Sachin Baban Gavhane
  • Rapid resolution process of clopidogrel base and a process for preparation of clopidogrel bisulfate polymorph-form I
    Patent number: 7446200
    Abstract: The present invention discloses a rapid resolution process of racemic clopidogrel base followed by conversion of the resolved (S) isomer to crystalline Clopidogrel bisulfate Form I. The invention also discloses novel racemization process of the unwanted (R) isomer of clopidogrel base. The invention further discloses an improved process for preparation of acid addition salts of clopidogrel.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: November 4, 2008
    Assignee: USV, Ltd.
    Inventors: Manoj Madhukarrao Deshpande, V. R. Tarur, Dhananjay Govind Sathe, Harish Kashniath Mondkar, Kamlesh Digambar Sawant, Tushar Anil Naik
  • Polymorph of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-y1] methyl piperidine hydrochloride (Donepezil hydrochloride) and a process for producing thereof
    Patent number: 7186842
    Abstract: The present invention discloses a novel, stable polymorph of 1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride commonly known as Donepezil hydrochloride. Further the present invention discloses a process for producing Donepezil HCl amorphous and its polymorph Form (VI).
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: March 6, 2007
    Assignee: USV, Ltd.
    Inventors: Umesh P. Aher, Venkatasubramanian R. Tarur, Dhananjay Govind Sathe, Avinash Venkataraman Naidu, Kamlesh Digambar Sawant
  • Weight loss product
    Patent number: 6420350
    Abstract: Supplement compositions designed to support weight loss and increase energy.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: July 16, 2002
    Assignee: Goen Group, Inc.
    Inventor: Albert M Fleischner
  • Portable plumbing sprinkler head array
    Patent number: D668742
    Type: Grant
    Filed: September 21, 2011
    Date of Patent: October 9, 2012
    Inventor: Philip English