Abstract: Aromatic 1,4-benxodiazepines with fused 5- or 6-membered heterocyclic rings which are antagonists of cholecystokinins and/or gastrin, and are useful in the treatment or prevention of CCK-related and/or gastrin-related disorders of the gastrointestinal, central nervous and appetite regulatory systems; compositions comprising these compounds; and methods of treatment employing these compounds.
Type:
Grant
Filed:
December 23, 1986
Date of Patent:
April 5, 1988
Assignee:
Merck & Co., Inc.
Inventors:
Roger M. Freidinger, Mark G. Bock, Ben E. Evans