Abstract: Repellent compositions which contain aromatic aldehydes such as cinnamic aldehyde, .alpha.-hexyl cinnamic aldehyde and/or coniferyl aldehyde are provided, together with methods for their use as repellents for pests including flies, cockroaches, aphids, silverleaf white flies, mosquitoes, ticks, fleas, lice, leafhoppers, thrips, two-spotted spider mites, snails, slugs, biting midges, earwigs, and moths. Also provided are stabilized .alpha.-hexylcinnamic aldehyde (HCA) compositions which reduce the evaporation rate of HCA and/or induce HCA to evaporate at a constant rate over time.
Type:
Grant
Filed:
December 24, 1996
Date of Patent:
August 11, 1998
Assignee:
Proguard, Inc.
Inventors:
Ralph W. Emerson, Bradford G. Crandall, Jr.
Abstract: This invention relates to methods for the utilization of sucrose phosphate synthase encoding sequences to modify the soluble solids in plant sink tissue.
Abstract: The present invention provides methods and compositions for inhibiting microbial growth through the use of flavonoid aldehydes or alcohols for the purpose of disinfecting contaminated environments. The methods include the step of contacting the unsterile area with an amount of a flavonoid aldehyde or alcohol sufficient to control growth of pathogenic microbes. The aldehyde or alcohol can be provided in a variety of formulations.
Type:
Grant
Filed:
November 22, 1995
Date of Patent:
April 14, 1998
Assignee:
Proguard, Inc.
Inventors:
Ralph W. Emerson, Bradford G. Crandall, Jr.
Abstract: Methods and compositions are provided for detecting antigens having a specific epitope associated with melanoma and prostatic carcinoma. The epitope is present in melanoma cells and prostatic cancer cells but is essentially absent from melanocytes and normal prostatic tissue. The antibody can be used in diagnostic methods for histochemical detection of human melanoma and prostate carcinoma, of various progression stages and in treatment of melanoma and prostate carcinoma.
Abstract: Neurospora crassa transformations are employed for production of heterologous proteins, where DNA constructs are prepared using a foreign gene under transcriptional and translational regulatory regions functional in Neurospora. A functional signal sequence is provided for secretion of the heterologous gene product. An auxotrophic Neurospora host is employed and transformed by the combination of the subject construct and a complementing gene. The resulting transformants provide for efficient secretion of the heterologous product.
Type:
Grant
Filed:
June 2, 1992
Date of Patent:
December 9, 1997
Assignee:
Hawaii Biotechnology Group, Inc.
Inventors:
W. Dorsey Stuart, John M. Ivy, Kenneth Koo
Abstract: A method of inducing a temporary substantial paralysis of an area of interest in a patient undergoing a medical procedure is provided. The method involves administering a therapeutically effective amount of vasoactive intestinal peptide (VIP) admixed with a pharmaceutically acceptable carrier to a patient undergoing an endoscopy or other medical procedure.
Abstract: Methods and compositions based upon natural aromatic aldehydes are provided, which find use as pesticides. The pesticides are formulated in a variety of ways, including dusts, sprays, shampoos and soaps, and can be bound to a solid support or provided as bait or directly impregnated into organic matter infested by or susceptible to infestation by a target pest. Pests controlled include mosquitos, lice, ants, cockroaches, lice, and ticks.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
October 14, 1997
Assignee:
Proguard, Inc.
Inventors:
Ralph W. Emerson, Bradford G. Crandall, Jr.
Abstract: Sucrose phosphate synthase (SPS), its process for preparation, its cDNA, and utilization of cDNA to modify the expression of SPS in the plant cells are provided.
Type:
Grant
Filed:
December 27, 1993
Date of Patent:
September 9, 1997
Assignee:
Calgene, Inc.
Inventors:
Charles Van Assche, Danielle Lando, Jean Michel Bruneau, Toni Alois Voelker, Monica Gervais
Abstract: A new oxido reductase enzyme activity obtainable from P. chrysogenum, involved in the production of .beta.-lactams, the set of genes encoding said enzyme activity, and a method to enhance said production by using the above-mentioned oxido reductase system and other oxido reductase systems or genes encoding for the same have been disclosed.
Type:
Grant
Filed:
July 12, 1994
Date of Patent:
July 29, 1997
Assignee:
Gist-Brocades, B.V.
Inventors:
Yair Aharonowitz, Lucia Helena Maria Van Der Voort, Gerald Cohen, Roelof Ary Lans Bovenberg, Rachel Schreiber, Anat Argaman, Yossef Av-Gay, Helena Maria Nan, Alfred Kattevilder, Harriet Pa Lissa, Henk Van Liempt
Abstract: Methods and compositions employing saponin as synergist in combination with a natural product, such as an aromatic aldehyde, are provided for controlling the colonization and/or growth of plant and animal pathogens, such as fungi, insects, arachnids and non-aquatic mollusks, on materials such as plants, plant parts and agricultural products before, during, after and/or processing. The invention finds use in treating agricultural crops for pathogenic organisms which colonize the surfaces of plant parts and tissues and controlling the level of toxic metabolites present in consumable products derived from plant materials, as well as reducing the health risk associated with their consumption. A method of employing saponin to kill nematodes is also provided.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
June 17, 1997
Assignee:
Proguard, Inc.
Inventors:
Ralph W. Emerson, Bradford G. Crandall, Jr.
Abstract: Intraocular devices which are capable of sustained release of a cell proliferation modulating agent, together with methods for their preparation and use, are provided. The intraocular devices are implanted in the tissue, and the drug is released from the intraocular device such that the drug is substantially retained within the implant region. The device may be used to inhibit cellular proliferation around the implant. The device can be provided as a kit, preferably in a form suitable for use.
Abstract: Brassica plants and seeds comprising nucleic acid sequences and methods for their use are provided which afford seed-specific transcription in order to modulate or modify expression in seed particularly in embryo cells. Transcriptional initiation regions are identified and isolated from plant cells such as seed embryo and seed coat and used to prepare expression cassettes which may then be transformed into plants cells for seed specific transcription. The method finds particular use in conjunction with modifying fatty acid production in seed tissue.
Abstract: Methods and compositions are provided for protecting antigens having a specific epitope associated with Melanoma. The epitope is present in melanoma cells but is essentially absent from melanocytes cites or other human tumor cells. The antibody can be used in diagnostic methods for histochemical detection of human melanoma of various progression stages and in treatment of melanoma.
Abstract: Plant species are produced by cocultivation transformation of cotyledon shoot cultures with a foreign gene followed by regeneration of plants from transformed cells, thereby producing plants capable of expressing the foreign gene. Particularly, tomato shoot cultures are employed and are transformed employing a manipulated Agrobacterium transformation system, followed by regeneration of the transformed plant tissue into plants.
Abstract: Plants, plant tissues and plant seeds which are resistant to inhibition by sulfonylurea and/or imidazolinone herbicides are provided. In particular, domestic lettuce varieties having resistance to herbicides which target the enzyme acetolactate synthase are provided. The resistant plants find use in areas where weed growth is controlled by sulfonylurea and/or imidazolinone herbicides.