Abstract: The present disclosure provides tissue collection devices comprising biosensors that can be used for the detection of target analytes, such as nucleic acids and proteins, including antibodies and enzymes.
Abstract: The present invention provides an apparatus and methods for the electrical detection of molecular interactions between a probe molecule and a protein or peptide target molecule, but without requiring the use of electrochemical or other reporters to obtain measurable signals. The methods can be used for electrical detection of molecular interactions between probe molecules bound to defined regions of an array and protein or peptide target molecules which are permitted to interact with the probe molecules.
Type:
Grant
Filed:
February 17, 2000
Date of Patent:
November 30, 2004
Assignee:
Motorola, Inc.
Inventors:
Changming Li, Jaymie Robin Sawyer, Vi-En Choong, George Maracas, Peiming Zhang
Abstract: The field of the invention is generally related to pharmaceutical agents useful in treating graft-versus-host disease (GVHD) in patients that have received allogenic bone marrow transplants.
Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
Type:
Grant
Filed:
March 8, 2000
Date of Patent:
July 13, 2004
Assignee:
Clinical Micro Systems, Inc.
Inventors:
Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen D. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
Abstract: The invention relates to novel insulin activity (IA) proteins and nucleic acids. The Invention further relates to the use of the IA proteins in the treatment of insulin related disorders such as type 1 diabetes and type 2 diabetes.
Abstract: The present invention relates to the treatment of wood, and is particularly concerned with a method for increasing the permeability of wood, especially moist wood.
Type:
Grant
Filed:
May 8, 2003
Date of Patent:
June 1, 2004
Assignee:
The University Of Melbourne
Inventors:
Peter Vinden, Francisco Javier Romero, Grigory Torgovnikov
Abstract: The invention relates to the use of signal processing methods in order to acheive higher signal to noise ratios, to increase the detection limits of target analytes. These techniques include the monitoring of the output signal at higher harmonic frequencies.
Type:
Grant
Filed:
September 17, 1999
Date of Patent:
May 25, 2004
Assignee:
Clinical Micro Sensors, Inc.
Inventors:
Hau H. Duong, Stephen D. O'Connor, Robert H. Terbrueggen, Jon Faiz Kayyem, Gary T. Olsen, Daniel A. Litvack, Javier Gonzalez
Abstract: The invention relates to novel targeted magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances.
Type:
Grant
Filed:
November 16, 2000
Date of Patent:
March 30, 2004
Assignee:
Research Corporation Technologies, Inc.
Inventors:
Thomas Meade, Scott Fraser, Russell Jacobs
Abstract: The invention relates to compositions and methods useful in the detection of nucleic acids using a variety of amplification techniques, including both signal amplification and target amplification. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the nucleic acid, either directly or indirectly, to allow electronic detection of the ETM using an electrode.
Type:
Grant
Filed:
July 20, 2000
Date of Patent:
February 3, 2004
Assignee:
Clinical Micro Sensors, Inc.
Inventors:
Gary Blackburn, Bruce D. Irvine, Jon Faiz Kayyem, Edward Lewis Sheldon, III, Robert H. Terbrueggen
Abstract: The invention relates to novel xylanase activity (XA) proteins and nucleic acids. The invention further relates to the use of the XA proteins in the process of pulp bleaching.