Abstract: Systems and methods for analyzing a sample are disclosed. The system may include a light source operable to transmit light onto the sample, a detector operable to detect intensity of the light emitted from the sample, and a power modulator. The power modulator modulates the light source power such that light is emitted from the light source in more than one mode to reduce changes in the emitted light due to temperature changes in the light source.

Abstract: A method and apparatus for obtaining and displaying in real time an image of an object obtained by one modality such that the image corresponds to a line of view established by another modality.

Abstract: Systems and methods for providing analog to digital conversion with improved dynamic range. Multiple low cost analog to digital converters may be used in parallel to provide the dynamic range of a single high resolution analog to digital converter that would otherwise be available only at very high cost. One application is an orthogonal frequency division multiplexing (OFDM) digital receiver which requires high dynamic range analog to digital conversion for accurate reception.

Abstract: The present invention generally provides a rapid efficient method for analyzing polymorphic or biallelic markers, and arrays for carrying out these analyses. In general, the methods of the present invention employ arrays of oligonucleotide probes that are complementary to target nucleic acids which correspond to the marker sequences of an individual. The probes are typically arranged in detection blocks, each block being capable of discriminating the three genotypes for a given marker, e.g., the heterozygote or either of the two homozygotes. The method allows for rapid, automatable analysis of genetic linkage to even complex polygenic traits.

Abstract: Systems and methods for remotely monitoring the execution of computer programs are provided. Monitoring instructions are added the computer program so that during execution of the program, data may be collected regarding the program execution. The collected data may be automatically sent to a remote system or site for analysis. The monitoring instructions create little or no performance impact on the client yet provide valuable information to the developer of the program. Additionally, the monitoring instructions may be changes during computer program development.

Abstract: A computer system for analyzing nucleic acid sequences is provided. The computer system is used to calculate probabilities for determining unknown bases by analyzing the fluorescence intensities of hybridized nucleic acid probes on biological chips. Additionally, information from multiple experiments is utilized to improve the accuracy of calling unknown bases.

Abstract: Systems and methods for detecting differences in sample polymers, such as nucleic acid sequences, are provided. Hybridization affinity information for the sample polymers is clustered so that the differences, if any, between or among the sample polymers can be readily identified. By clustering the hybridization affinity information of the sample polymers, differences in the sample polymers can be accurately achieved even in the presence of random and systematic errors.

Abstract: An adaptive reception and transmission technique according to one embodiment of the invention offers the advantages of adaptive reception transmission using feedback without the associated mobile radio complexity increase and information capacity penalty. The technique has been developed to exploit structured variation which occurs in the multipath fading present in the wireless antenna array channel. Thus, multipath propagation effects are explicitly accounted for in the problem approach. The technique is blind in that the antenna beam is formed in the absence of explicit knowledge of the array geometry, and without the necessity of array calibration or mobile feedback. The basic approach is to estimate the optimum receive and transmit antenna beam pattern based on certain statistical properties of the received antenna array signals. The optimum receive and transmit beam pattern is found by solving an optimization equation.