Abstract: The present invention provides a method for typing of alleles of the Minor Histocompatibility Antigen HA-1 in a sample. The method comprises: a) contacting the genomic polynucleic acids in the sample with at least one pair of primers, whereby the 51- and/or the 31-primer of the at least one pair of primers specifically hybridize to target regions comprising polymorphic nucleotides in the alleles, and performing an amplification reaction; b) for each of the at least one pair of primers detecting whether or not in step a) an amplification product is formed; c) inferring from the result of step b) which HA-1 allele is present in the sample. The present invention also provides a method for genomic typing of alleles of the Minor Histocompatibility Antigen HA-1 in a sample.

Abstract: This invention provides an isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth. This invention provides a polypeptide encoded by the isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth. This invention also provides a polypeptide which comprise the portion of the mutated collagen X capable of regulating bone growth. This invention further provides a transgenic animal comprising an isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth.

Abstract: The invention provides a portable or hand-held vacuum cleaner that includes a filtration system or filtration module that can pick up particles and contaminants. It has a first passive stage (such as a HEPA filter) to collect dust particles, and contaminants over a predetermined size. The invention also includes an active stage filter(such as an ozone generator) which may include one or more chemical (or biological) agents effective to kill bacteria, viruses, and the like.

Abstract: A method for purifying water including nitrification by aerobic bacteria and denitrification by anaerobic bacteria in an apparatus by providing an elongated, closed water channel.

Abstract: The invention provides a gas mask comprising a face piece including a transparent eye covering, and including a space to allow air to circulate around the nose and mouth of a wearer, and having an airtight seal to prevent contaminated air from entering the gas mask; a filtration apparatus containing an active stage and a passive stage, the passive stage for filtering out particles above a predetermined size, and including adsorbent media for removing toxic or harmful substances and fluids from the contaminated air, the active stage containing at least one agent to kill ambient bacteria and viruses; an intake vent permitting contaminated air to enter into the filtration system; at least one passageway connecting the filtration apparatus to the space around the nose and mouth of the wearer; and an exhalation port through which exhaled air may be expelled.

Abstract: An air purifier includes a housing having a purification chamber with an inlet to the housing for drawing in contaminated air and an outlet from the housing for releasing purified air. The air purifier also includes an inlet for introducing a fluid containing a source of antimicrobial ions into the purification chamber. The air purifier also includes at least one microwave radiation source and at least one ultraviolet radiation source which work in combination to increase the effectiveness of the antimicrobial ions. Also included are filters for removing airborne particulates and adsorbing antimicrobial ions from treated air.

Abstract: The present invention relates to an internal anterior transpedicular fixation system and a method for rigidly fixing the spine anteriorly at the level above and below a thoracolumbar burst fracture or tumor. The internal anterior transpedicular fixation system has a support member defining a plurality of engaging portions thereon. At least two of the engaging portions are spaced longitudinally from each other and adapted to span at least one verteba. At least two of the engaging portions are spaced laterally from each other and adapted to span a lateral distance of the verteba. A plurality of fixation elements are provided to mount the engaging portions onto the verteba. Thereby, the support member is restrained from rotational or translational movement relative to the verteba.

Abstract: For the early detection of blindness-causing diabetic retinopathy, an apparatus for measuring the autofluorescence of the cornea of an eye, comprising means for tangentially illuminating the cornea, means for receiving the autofluorescent radiation generated in the cornea by this illumination, and means for processing the measured autofluorescent radiation, wherein the means for tangentially illuminating the cornea comprises at least one light source which radiates blue light and at least one filter which transmits at least a part of the blue light in a light path to the cornea, and the means for receiving the autofluorescent radiation generated in the cornea comprises at least one filter which transmits green light.

Abstract: A computerized lottery or wagering system includes a game generator and a plurality of vendor stations that permit players to select game parameters. The game is graphically portrayed in animation as one or more races (horse race, dog race, car race, motorcycle race, etc.). The game may entail win, place, show, quinella, exacta/perfecta, trifecta, or series bets. At a predetermined time for each game, selection of game parameters for that game is ended and a winning sequence of numbers is randomly generated. The game generator selects and seamlessly composes a plurality of video segments into an animated video sequence of the race(s) corresponding to the winning sequence of numbers, for broadcast via RF transmission, microwave transmission, fiber optic cabling or closed circuit television lines. The video segments are rendered directly to a compressed digital format to maintain the video image in the highest quality possible.

Abstract: A condiment grinder includes a housing, a chamber within or attached to the housing for containing articles to the ground such as pepper seeds. A trigger is attached to the housing. An elongate piston extends through the chamber and has serrations along a portion of its length. A linkage co-operates with the trigger and the piston to transmit reciprocal movement of the trigger to reciprocal movement of the piston. A grinding aperture adjacent to the chamber has an internal periphery and is co-operative throughout its internal periphery with the serrations of the piston to grind the articles upon reciprocation of the piston.

Abstract: The invention provides a spinal disc implant comprising two side walls which are opposed and substantially parallel spaced apart by a front wall and a back wall to define an interior space. The side walls define substantially elliptical curves joining the front and back walls. The front wall is also curved and the back wall may be either curved or straight. The walls may have openings or holes which may be circular or elliptical in shape. The upper and lower edges of the implant have a plurality of teeth extending therefrom for engaging adjacent vertebrae. The implant is made of a biocompatible metal such as titanium or an alloy thereof, and the first and second sides tapering from the second end to the first end. The interior space has a porous hydroxyapatite block shaped to fill the interior space. The porous hydroxyapatite substance helps the prosthesis integrate into the vertebral structure by allowing into the pores.

Abstract: An intelligent video monitor system includes a video monitoring unit having a plurality of detectors arranged in an array for monitoring for an intrusion within a defined area. A plurality of video receiver units are dispersed with and arranged in an array along with the plurality of detectors for monitoring video within the defined area, each of the plurality of video receiver units arranged for monitoring a portion of the defined area. Processing and control circuitry processes outputs from the plurality of detectors and video receiver units and automatically selects at least one of the video receiver units based on the processed outputs and a wireless transmitter transmits the output from the automatically selected at least one video receiver unit. A wireless receiver unit receives the output signal transmitted by the transmitter. The receiver unit includes an antenna for receiving the signal output from the transmitter.

Abstract: A method of packaging a nuclear reactor vessel for decommissioning and removal, wherein closure plates are installed onto the vessel, concrete is injected into the vessel, shielding material is installed around the exterior of the vessel and the main nozzles of the vessel, the installed shielding materials are welded to themselves, the vessel is placed on shipping cradles and attached to longitudinal restraint mechanisms for transport.

Abstract: In the paper coating operation a wet or dry edge from coating composition is formed on the, seen in the direction of movement of the paper web, downstream side of the doctor, the so-called stalagmite formation. This stalagmite formation leads to various problems in the papermaking process and especially occurs at high speeds of the paper web and/or a high solids content of the coating composition, which two operating conditions are exactly required to obtain a maximum paper yield and a high paper quality. According to the invention the stalagmite formation is effectively prevented by supplying a fluid inhibiting the stalagmite formation to an area bounded, on the one hand, by the paper web and, on the other hand, by the above side of the doctor blade.

Abstract: An improved porous ceramic biomaterial is disclosed in which a polymer such as polylactic acid is polymerized in situ to fill the micropores substantially without filling the macropores. The polymer reinforcement helps improve the strength of the implant while preserving its ability to support ingrowth of bone to help integrate the implant into its surgical environment.

Abstract: This invention provides an isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of the DNA regulates bone growth. This invention provides a polypeptide encoded by the isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of the DNA regulates bone growth. This invention also provides a polypeptide which comprise the portion of the mutated collagen X capable of regulating bone growth. This invention further provides a transgenic animal comprising an isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of the DNA regulates bone growth.

Abstract: The oligonucleotides: (i) the 23-mer 5′-TTTGTTACTGTGGTAGATACTAC-3′ (SEQ ID NO: 1) or the 23-mer which is complementary to it; (ii) a 23-mer derived from (i) by from 1 to 5 nucleotide substitutions; (iii) a 23+-mer having a 3′ terminal sequence consisting of (i) or (ii); (iv) a fragment of (i) or (ii) having a length of from 8 to 18 nucleotides; (v) the 25-mer 5′-GAAAAATAAACTGTAAATCATATTC-3′ (SEQ ID NO: 2) or the 25-mer which is complementary to it; (vi) a 25-mer derived from (v) by from 1 to 5 nucleotide substitutions; (vii) a 25+-mer having a 3′ terminal sequence consisting of (v) or (vi); (viii) the 28-mer 5′-GAAAAATAAACTGTAAATCATATTCTTC-3′ (SEQ ID NO: 10) or the 28-mer which is complementary to it; (ix) the 28-mer 5′-GAAAAATAAACTGTAAATCATATTCCTC-3′ (SEQ ID NO: 18) or the 28-mer which is complementary to it; (x) a 28-mer derived from (viii) or (ix) by from 1 to 5 nucleotide substitutions; (xi) a 28+-mer having a 3′ terminal seq