Abstract: A method for preventing the sickling of sickle cells in a patient having sickle cell disease, the method which comprises administering to the patient a therapeutically effective amount of a compound having the formula: ##STR1## wherein X.sup.- is selected from the group consisting of iodide, chloride, bromide, hydroxyl, nitrite, phosphate and acetate.
Abstract: A process and apparatus for continuously treating infectious waste, which comprises: (a) introducing bulk unseparated infectious waste material into a receiving container means, the receiving container means adapted to receive a flow of disinfectant such that the receiving container means remains substantially free of infectious contaminants; (b) shredding the waste material by a primary shredding means; (c) separating the shredded waste material from waste residue in a separation tank means having a predetermined fluid level thereby producing a waste slurry; (d) pumping the waste slurry into a reactor vessel means; (e) contacting the waste slurry with a disinfecting fluid in the reactor vessel means for a sufficient amount of time to disinfect the waste slurry; and (f) dewatering the disinfected waste slurry to recover solid disinfected waste material.
Abstract: A method of treating lead contaminated soil to reduce the amount of mobile lead contained in the soil, the method which comprises: (a) providing an agent selected from the group consisting of inorganic phosphate compounds, inorganic phosphite compounds and mixtures thereof; and (b) contacting the agent with the soil to react the agent with the lead and form immobilized, acid-insoluble lead compounds, thereby reducing the amount of mobile lead in the soil.
Type:
Grant
Filed:
December 28, 1990
Date of Patent:
November 10, 1992
Assignee:
Rheox, Inc.
Inventors:
Charles A. Cody, Steven J. Kemnetz, William Bronner
Abstract: A process for deinking wastepaper with an aqueous system, which includes:(a) contacting wastepaper with an aqueous system which contains an agent of one or more organically modified smectite-type clays; and(b) recovering deinked paper pulp from the aqueous system.
Abstract: An extended release pharmaceutical formulation adapted to approach zero order release of drug over a 12 to at least 24 hour period, comprised of a mixture of 0 to aobut 50% of an immediate release particle containing a drug, inert substrate and binder, coated with talc and up to 100% of an extended release particle comprising the immediate release particle coated with a dissolution modifying system containing plasticizers and a film forming agent.
Type:
Grant
Filed:
January 24, 1990
Date of Patent:
July 28, 1992
Assignee:
KV Pharmaceutical Company
Inventors:
George N. Paradissis, James A. Garegnani, Roy S. Whaley
Abstract: A hydrostatic system includes a variable displacement hydraulic motor whose absorption volume is adjusted by a pressure regulator, depending on the rpms generated by the power source driving the system. The apparatus enables the variable displacement motor to fully utilize the drive power avaiable from the power source over a range of operating speeds.
Abstract: A controlled-release organic nitrate formulation for once-per-day oral administration is provided by spheres having a core which includes an organic nitrate, and a membrane surrounding the core composed of a pharmaceutically acceptable, film forming polymer. The film forming polymer is effective to permit release of the organic nitrate from the spheres, over a daily dosing period, at a rate that achieves a therapeutically effective level of the organic nitrate, while effecting a drug holiday towards a latter portion of the daily dosing period so as not to induce tolerance.
Type:
Grant
Filed:
May 5, 1989
Date of Patent:
June 16, 1992
Assignee:
KV Pharmaceutical Company
Inventors:
George N. Paradissis, James A. Garegnani, Roy S. Whaley
Abstract: The invention is directed to a carbonated beverage dispenser and to a method of dispensing carbonated beverage. The dispenser comprises a canister having a side wall, a bottom wall and an open end with a removable lid for closing the open end during operation. A dispensing tube having a puncturing end is provided in the bottom of the canister for puncturing a beverage container loaded into the canister. The dispensing tube is connected to a flow control valve for controlling dispensing of beverage from the container. Low pressure beverage containers such as plastic or glass bottles and aluminum cans can be used in the dispenser by shaking the canister and container of beverage therein to agitate the carbonated beverage and release dissolved carbon dioxide gas prior to dispensing a serving in order to eventually dispense the entire contents of the beverage container.
Abstract: A process and apparatus for continuously treating infectious waste, which comprises: (a) introducing bulk unseparated infectious waste material into a receiving container, the receiving container adapted to receive a flow of disinfectant such that the receiving container remains substantially free of infectious contaminants; (b) shredding the waste material by a primary shredder; (c) separating the shredded waste material from waste residue in a separation tank having a predetermined fluid level thereby producing a waste slurry; (d) pumping the waste slurry into a reactor vessel; (e) contacting the waste slurry with a disinfecting fluid in the reactor vessel for a sufficient amount of time to disinfect the waste slurry; and (f) dewatering the disinfected waste slurry to recover solid disinfected waste material.
Abstract: A method for preventing the sickling of sickle cells in a patient having sickle cell disease, the method which comprises administering to the patient a therapeutically effective amount of a compound having the formula: ##STR1## wherein X.sup.- is selected from the group consisting of iodide, chloride, bromide, hydroxyl, nitrite, phosphate and acetate.
Abstract: A solid fuel burning stove is provided and includes a housing within which a combustion chamber is located. The combustion chamber receives combustion air via an adjustable inlet formed through a channel member running along the base of the housing. The channel member defines a combustion air duct which communicates with a combustion air intake in the rear wall of the housing. Combustion air is drawn into the stove via the air intake and is forced through the combustion air duct by a fan. The combustion air passes through the adjustable inlet into the combustion chamber. A fire box is located within the combustion chamber above the adjustable inlet and holds the solid fuel to be combusted. Hot flue gases heat air flowing through a plurality of heat exchange tubes passing through the combustion chamber. The heated air flowing through the heat exchange tubes is directed into the room in which the stove is located via a plurality of vents in the front wall of the housing.
Type:
Grant
Filed:
July 25, 1991
Date of Patent:
April 21, 1992
Inventors:
Alexander M. Gulutzen, W. Stanley Gulutzen
Abstract: A soft shoe in which there is a non-snag liner having only one seam exposed to the inside of the shoe, and with no exposed stitching on the inside of the shoe. The lining is made of a fabric such as tricot which prevents heel slip and prevents snags or runs in hosiery. The shoe may also be provided with padding around the upper, a soft outsole, and an inner pad for a cushioning effect.
Abstract: A heat stable, purified, pyrogen-free, heat sterilized fraction of hyaluronic acid suitable for use in formulations for intra-articular treatment of animals which includes minor amounts of sulphated mucopolysaccharides, sulphated ash, chlorides, solvents and less than 0.6% protein, having a molecular weight of less than 750,000 and exhibiting a specific absorbance of a 1% solution at A257nm of less than 3. A formulation for intra-articular treatment of animals including an aqueous solution of the heat stable fraction of hyaluronic acid and preservatives, such as sodium benzoate, methylparaben and propylparaben, having a pH of 6.8-8.0 at 25.degree. C. A method of preparing a formulation for intra-articular treatment of animals involving adding and dissolving methyl parahydroxybenzoate, propyl parahydroxybenzoate and sodium benzoate in hot water, mixing the preservative solution to dissolve the parabens, adding sodium hyaluronate in the solution, adjusting the pH of the resultant solution to 6.8-8.
Abstract: A metal porcelain dental restoration for filling an edentulous region is provided. The dental restoration comprises a first layer of a thin metal foil which closely fits the contours of the two abutment teeth on either side of the edentulous region, a layer of ceramic on the first metal foil layer, a second layer of thin metal foil connected to the ceramic layer and extending at least across the joint from the abutment teeth to the edentulous region and a ceramic build-up to fill the edentulous region.
Abstract: A method of treating a horse suffering from navicular disease which involves administering an amount of a composition including pentoxifylline in a daily dose for a sufficient period of time effective to alleviate lameness in horses resulting from navicular disease. A pharmaceutical composition including an effective amount of pentoxifylline and a pharmaceutically acceptable carrier for alleviating lameness resulting from navicular disease.
Abstract: Solid delivery systems which at body temperature exhibit controlled release and bioadherence characteristics. These systems are emulsions which are water in oil in nature and whose internal phase is greater than that of the external phase. That is, the internal phase comprises at least 60% of the system.
Abstract: A method for the treatment of immune system disorders in humans by administration of pp14; derivatives, fragments, or subunits of pp14; or monoclonal antibodies thereto. The method may be used to treat allergic disorders, autoimmune disorders, inflammatory disorders, lymphoproliferation disorders, and neoplastic disorders. Monoclonal antibodies to pp14, and the hybridoma cell lines which produce them. A method for the detection and quantitation of pp14 using monoclonal antibodies thereto, as well as a method for the purification of pp14 using an affinity or immuno-precipitation reaction.
Abstract: A method for producing a food product comprising the steps of providing a base layer of cheese; covering the base with a layer of previously popped popcorn; adding a second layer of cheese on top of and in the interstices of the popcorn layer; heating to melt the cheese and to bond the second layer of cheese and popcorn to the base, thereby forming a structure having a plurality of layers; freezing the structure to form a frozen structure; and freeze-drying the frozen structure; and the resulting food product.
Abstract: Method and apparatus for automatically cleaning a roll for handling sheet stock while in service, including signale ended reciprocally actuated scrubbing of a fully roll surface width polishing surface swingingly engaged with the roll surface to provide effective cleaning action without leaving residual scars on the roll surface. Single ended actuation of the scrubbing action is enhanced with special self aligning bearings.
Abstract: A metal foil is provided for use in a metal-porcelain dental restoration, which metal foil provides improved color qualities to the finished restoration and improved bonding of the metal to the porcelain. The metal foil is made of an alloy comprising a major amount of gold, an amount of platinum or palladium, and an amount of a non-precious metal. An improved dental veneer and dental bridge can also be made using the metal foil of the invention.