Patents Represented by Attorney, Agent or Law Firm Rothwell, Figg, Ernst & Kurz
  • Patent number: 6034301
    Abstract: A deposit of the Asgrow Seed Company soybean cultivar 932311522929 disclosed above and recited in the appended claims has been made with the American Type Culture Collection (ATCC), 10801 University Boulevard, Manassas, Va., 20110. The date of deposit was Oct. 27, 1997. The deposit of 2,500 seeds were taken from the same deposit maintained by Asgrow Seed Company since prior to the filing date of this application. All restrictions upon the deposit have been removed, and the deposit is intended to meet all of the requirements of 37 C.F.R. .sctn.1.801-1.809. The ATCC accession number is PTA-878. The deposit will be maintained in the depository for a period of 30 years, or 5 years after the last request, or for the effective life of the patent, whichever is longer, and will be replaced as necessary during that period.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: March 7, 2000
    Assignee: Monsanto Corporation
    Inventor: Beth Annice Holmes
  • Patent number: 6035004
    Abstract: An inexpensive, compact digital radio receiver corrects IQ imbalance, non-orthogonal I and Q phases, and DC offset by a DSP. The digital radio receiver is equipped with an antenna, an RF/IF converter for converting a radio frequency into an intermediate frequency, an IQ separator for separating I and Q, a filter for eliminating a noise such as a radio frequency, a multiplying sampler for sampling the output of the filter, and a digital signal processing unit mainly comprised of the DSP which implements an algorithm for estimating and correcting an IQ distortion and also performs quadrature phase demodulation. The IQ distortion can be removed inexpensively by making use of a part of a standard radio operation, hardly requiring the use of hardware for adjustment.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: March 7, 2000
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventor: Hiroshi Nakata
  • Patent number: 6034303
    Abstract: A novel soybean cultivar, designated 932359514320, is disclosed. The invention relates to the seeds of soybean cultivar 932359514320, to the plants of soybean 932359514320 and to methods for producing a soybean plant produced by crossing the cultivar 932359514320 with itself or another soybean variety. The invention further relates to hybrid soybean seeds and plants produced by crossing the cultivar 932359514320 with another soybean cultivar.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: March 7, 2000
    Assignee: Monsanto Corporation
    Inventor: Beth Annice Holmes
  • Patent number: 6035288
    Abstract: A computer-implemented method and system for negotiating the purchase of goods and/or services by customers utilizes a simulated human merchant having predefined behavioral attributes. An algorithm representing behavioral attributes of a simulated human merchant is used to receive customer input data relating to particular goods and/or services desired to be purchased. The customer input data is processed to generate merchant responses to the customer input data, and the sale of goods and/or services are agreed to at a particular price as a result of processing of customer replies to merchant responses according to the algorithm.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: March 7, 2000
    Assignee: Cendant Publishing, Inc.
    Inventor: Robert S. Solomon
  • Patent number: 6033857
    Abstract: The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast cancer predisposing gene (BRCA2), some mutant alleles of which cause susceptibility to cancer, in particular breast cancer. More specifically, the invention relates to germline mutations in the BRCA2 gene and their use in the diagnosis of predisposition to breast cancer. The present invention further relates to somatic mutations in the BRCA2 gene in human breast cancer and their use in the diagnosis and prognosis of human breast cancer. Additionally, the invention relates to somatic mutations in the BRCA2 gene in other human cancers and their use in the diagnosis and prognosis of human cancers. The invention also relates to the therapy of human cancers which have a mutation in the BRCA2 gene, including gene therapy, protein replacement therapy and protein mimetics.
    Type: Grant
    Filed: March 20, 1998
    Date of Patent: March 7, 2000
    Assignees: Myriad Genetics, Inc., Endo Recherche, Inc., HSC Research & Development Limited Parntership, Trustees of the Univ. of Pennsylvania
    Inventors: Sean V. Tavtigian, Alexander Kamb, Jacques Simard, Fergus Couch, Johanna M. Rommens, Barbara L. Weber
  • Patent number: 6034300
    Abstract: A novel soybean cultivar, designated 942220611985, is disclosed. The invention relates to the seeds of soybean cultivar 942220611985, to the plants of soybean 942220611985 and to methods for producing a soybean plant produced by crossing the cultivar 942220611985 with itself or another soybean variety. The invention further relates to hybrid soybean seeds and plants produced by crossing the cultivar 942220611985 with another soybean cultivar.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: March 7, 2000
    Assignee: Monsanto Corporation
    Inventor: Roger Lussenden
  • Patent number: 6031159
    Abstract: A novel soybean cultivar, designated 958088713716, is disclosed. The invention relates to the seeds of soybean cultivar 958088713716, to the plants of soybean 958088713716 and to methods for producing a soybean plant produced by crossing the cultivar 958088713716 with itself or another soybean variety. The invention further relates to hybrid soybean seeds and plants produced by crossing the cultivar 958088713716 with another soybean cultivar.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: February 29, 2000
    Assignee: Monsanto Corporation
    Inventor: Roger Lussenden
  • Patent number: 6030832
    Abstract: Recent evidence indicates that the carboxy-terminal region of the tumor suppressor protein BRCA1 is a functionally significant domain. Using the yeast two-hybrid assay and an in vitro biochemical assay, it is here shown that a protein, B112, interacts specifically with the carboxy-terminal segment of human BRCA1 from residue 1602 to 1863. A germ line truncation mutation, 1853ter, that removes the last 11 amino acids from the carboxy-terminus of BRCA1 abolishes not only the transcription activation function, but also binding to B112. The B112 protein is apparently the same as an uncharacterized protein known as CtIP, the sequence of which was previously deposited in GenBank. Screenings of a panel of 92 tumor cell lines for mutations in the B112/CtIP sequence have identified a number of missense variants, including a non-conserved lysine to glutamic acid change at codon 337 in the pancreatic cancer line, BxPC3.
    Type: Grant
    Filed: November 21, 1997
    Date of Patent: February 29, 2000
    Assignee: Myriad Genetics, Inc.
    Inventors: Alexander K. C. Wong, Paul L. Bartel, David H. -F. Teng, Sean V. Tavtigian
  • Patent number: 6031507
    Abstract: To obtain a high-performance antenna apparatus free from the shift of its focusing point, there are provided a plurality of pairs of horns, horns of each pair are arranged at opposite positions with respect to the center of the plurality of horns, and each pair of horns operates at a different frequency band.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: February 29, 2000
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventor: Katsuhiko Aoki
  • Patent number: 6030840
    Abstract: A method for the spectroscopic determination of a marker comprises:(a) contacting chelated lanthanide metal ions bound to a marker with a buffered solution comprising a detergent, an enhancer reagent and a polyanion, wherein the buffer maintains the pH of the solution within the range of about 3.5 to about 11.5 and the polyanion is present in sufficient concentration such that the lanthanide metal ion disassociates from the chelate complex and reassociates with the enhancer reagent, thereby transferring the lanthanide metal ion into fluorescent form; and(b) determining the amount of lanthanide metal ion liberated from the marker as a measure of the amount of marker present by subjecting the solution to a short radiation pulse and detecting the fluorescence of the lanthanide metal ion after the fluorescence from any background sources substantially has ceased.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: February 29, 2000
    Assignee: NEN Life Sciences, Inc.
    Inventors: Thomas Robert Mullinax, Margaret R. Cody, Mark N. Bobrow
  • Patent number: 6028172
    Abstract: A solid phase peptide synthesis reactor system and method of operating the reactor are provided. The reactor system includes a basket rotatable about an axis within a housing and a receiver which delivers fluid to, and collects fluid from, the housing. The basket has a perforate side wall against which a resin cake for the peptide synthesis is formed. The reactor and receiver form a loop or circuit through which solutions are circulated. The circulation of the solutions prevents the reactor from flooding so that the basket will not be submerged in solution and allows for the use of less liquid. Thus greater amino acid concentrations may be used. The method includes forming a resin cake of uniform depth on the wall of the spinning basket and spraying the solutions against the resin cake while spinning the basket. The solutions will pass through the resin cake and drain to the receiver to be circulated or recycled through the system or discharged from the system.
    Type: Grant
    Filed: March 9, 1999
    Date of Patent: February 22, 2000
    Assignee: Mallinckrodt Inc.
    Inventors: Nicholas Stepaniuk, Keith Tomazi, Michael C. Stapleton
  • Patent number: 6027709
    Abstract: New fluorescent cyanine dyes are useful as reporter groups for labeling biomolecules.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: February 22, 2000
    Assignee: Li-Cor Inc.
    Inventors: Garrick Murray Little, Ramesh Raghavachari, Narasimhachari Narayanan, Harry Leonard Osterman
  • Patent number: 6027892
    Abstract: Provided are antisense oligonucleotides directed against the raf-1 gene, Ha-ras gene and HER-2 gene, components of a signal transduction pathway involving oncogenes and their normal counterparts and leading to the phenotype of cellular radioresistance. Administration of these antisense oligonucleotides is shown to reverse the radioresistance phenotype in cells overexpressing HER-2 or a mutant form of Ha-ras. Methods and compositions for reversing radiation resistance among other conditions involving these genes are disclosed.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: February 22, 2000
    Inventors: Esther H. Chang, Kathleen F. Pirollo
  • Patent number: 6028253
    Abstract: A novel soybean cultivar, designated 41373519, is disclosed. The invention relates to the seeds of soybean cultivar 41373519, to the plants of soybean 41373519 and to methods for producing a soybean plant produced by crossing the cultivar 41373519 with itself or another soybean variety. The invention further relates to hybrid soybean seeds and plants produced by crossing the cultivar 41373519 with another soybean cultivar.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: February 22, 2000
    Assignee: Stine Seed Farm, Inc.
    Inventor: William H. Eby
  • Patent number: 6027923
    Abstract: The extensive synthesis ("amplification") of a nucleic acid sequence of interest is attained through a linked series of multi-cycle primer extension reactions (LLA). The primers used in each of the primer extension reactions of the process contain non-replicable elements that halt nucleic acid synthesis and thereby prevent the synthesized molecules from serving as templates in subsequent cycles. Synthesized molecules accumulate during primer extension in a mathematically linear fashion, thereby rendering the process relatively insensitive to contaminating nucleic acids. Multiple primer sets are employed, thereby ensuring the accumulation of a large number of copies of the nucleic acid sequence of interest. The invention also provides for the detection of an amplified nucleic acid sequence of interest, as well as reagent kits for carrying out the reaction.
    Type: Grant
    Filed: April 2, 1997
    Date of Patent: February 22, 2000
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Robert Bruce Wallace
  • Patent number: 6028180
    Abstract: An ink comprising water, a water-dissipatable polymer and one or more dyes having a benzene ring carrying a hydroxy group at each of the 1-, 3- and 5-positions and an azo group at each of the 2-, 4- and 6-positions or a tautomer thereof.Also claimed are certain dyes, compositions printer cartridges and ink jet printers.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: February 22, 2000
    Assignee: Zeneca Limited
    Inventors: Andrew Paul Shawcross, Gavin Wright, Barry Huston Meyrick, Mark Holbrook
  • Patent number: 6024817
    Abstract: A belt-shaped member cut into a predetermined length is fed from a feeding devices to a tire forming drum and is wound on its cylindrical peripheral surface. Center portions of the opposite ends of the belt-shaped member are pushed to be joined to each other and the side portions of at least one of the opposite ends of the belt-shaped member are held by upper and lower holding pawls. Such holding pawls are swung along an arcuate path so that both side portions of the opposite ends of the belt-shaped member are drawn near each other to abut against each other. The abutting end portions are pushed toward the peripheral surface of the drum by pushing devices for joining them together.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: February 15, 2000
    Assignee: Yokohama Rubber Company, Ltd.
    Inventors: Yoshinori Miyamoto, Hidemasa Sato, Jiro Agawa, Keizo Yamashita, Toshinari Matsumoto
  • Patent number: 6025172
    Abstract: The invention relates to the isolation from hazel (Corylus avellana L.) of the FAD2-N gene coding for the .DELTA.12 desaturase enzyme of the microsomal fraction and, in particular, provides the nucleotide sequence and the deduced amino-acid sequence of the gene and provides for the use of the FAD2-N gene as a probe for the isolation of other plant desaturases. The invention also relates to the use of the FAD2-N gene for altering desaturase levels and consequently the fatty-acid composition of the plant.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: February 15, 2000
    Assignee: Soremartec S.A.
    Inventors: Maria Dani, Sergio Catello
  • Patent number: D420618
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: February 15, 2000
    Inventor: John Minister
  • Patent number: D421449
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: March 7, 2000
    Inventor: Winston Wolfe