Abstract: The provision of Cephalosporium acremonium resistant to the aminoglycoside G418 allows the use of this aminoglycoside as a marker to select aminogylcoside-resistant cells of Cephalosporium acremonium from non-resistant cells of Cephalosporium acremonium. Aminoglycoside resistance can be imparted by transformation of Cephalosporium acremonium with a suitable vector.
Type:
Grant
Filed:
November 7, 1985
Date of Patent:
June 28, 1988
Inventors:
Miguel A. Penalva, Angeles Tourino, Cristina Patino, Florentina Sanchez, Victor Rubio, Jose M. Fernandez-Sousa