Abstract: The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.

Abstract: A sensor for the detection of an analyte, comprising a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the hologram changes as a result of a variation of a physical property occurring throughout the volume of the medium, wherein the medium is obtainable by formation in situ in the presence of a pore-forming agent, wherein the agent is not present in the sensor or does not react with the analyte and the sensor.

Abstract: The invention relates to receptors of catecholamines and their role in stem cell development and function.

Abstract: An ophthalmic device which comprises a holographic element comprising a medium comprising a phenylboronic acid group and, disposed therein, a hologram, wherein an optical characteristic of the element changes as a result of a variation of a physical property of the medium, and wherein the variation arises as a result of interaction between the medium and an analyte present in an ocular fluid.

Abstract: A novel on-line method is presented for the extraction and preconcentration of amino acids using a sol-gel coated column coupled to a conventional UV/vis detector. Extraction, stacking and focusing techniques are used in the preconcentration procedures. Sol-gel coatings are created by using N-Octadecyldimethyl[3(trimethoxysilyl)proply]ammonium chloride (C18-TMS) in the coating sol solutions. The resulting sol-gel coating carries a positive charge. For extraction, the pH of the samples is properly adjusted to impart a net negative charge to amino acids. A long plug of the sample is then passed through the sol-gel coated capillary to facilitate extraction via electrostatic interaction between the positively charged sol-gel coating and the negatively charged amino acid molecules. The focusing of the extracted amino acids is accomplished through desorption of the extracted amino acid molecules carried out by local pH change. The described procedure provides 150,000-fold enrichment effect for alanine.

Abstract: A method for irrigation of a wound, wherein the method involves the use of a reservoir housing containing a wound irrigation solution and a discharge means attached thereto, wherein the discharge means has multiple ports for directing a stream of the solution at a wound at an appropriate pressure.

Abstract: Control devices and kits of components of control devices are provided. The subject invention also provides systems for designing control devices and/or kits of components of control devices. A system user can provide data about an end user to an expert system via a user interface, and the expert system can use the data and a method for selecting appropriate components to design a control device and/or kit. The control device can be a self-referenced control device and can include a controller and a wearable interface.

Abstract: A plasma actuator incorporates a power source, a first electrode in contact with a first dielectric layer, a second electrode in contact with a second dielectric layer, and a ground electrode. The power source drives the first electrode with a first ac voltage pattern with respect to the ground electrode to produce a first plasma discharge, and a first electric field pattern in the flow region, and drives the second electrode with a second ac voltage pattern with respect to the ground electrode to produce a second plasma discharge in the flow region and a second electric field pattern in the flow region. The first and second electrodes are offset along the direction of flow and the first voltage pattern and the second voltage pattern have a phase difference such that the first and second electric fields drive flow in different portions of the flow region at different times.

Abstract: A photoluminescent sheet is disclosed. A photoluminescent sheet that includes a matrix resin layer, which is a thermosetting resin; a phosphor, which is included in the matrix resin layer and which converts the wavelength of light emitted from a blue LED; a curing agent, which is included in the matrix resin layer and which cures liquid thermosetting resin; and an additive, which is included in the matrix resin layer and which disperses the phosphor uniformly within the matrix resin layer, can implement white light from light having wavelengths corresponding to blue color.

Abstract: A semiconductor memory device is provided including: a spacer shaped floating gate formed on a semiconductor substrate; a dielectric layer spacer formed at one side wall of the floating gate; a third oxide layer formed over the floating gate and the dielectric layer; and a control gate formed over the third oxide layer. According to an embodiment, the structure of the floating gate in a plate shape whose center is concave is improved to the spacer structure, making it possible to minimize the size of the semiconductor memory device and to improve density. Moreover, a LOCOS process can be excluded while forming the floating gate, making it possible to more efficiently fabricate the device.

Abstract: A partial ovoidal FAIMS apparatus for separating ions is presented with inner and outer electrodes that have geometrically matched convex and concave partial ovoidal surfaces, respectively, that share at least one common defining axis and display a nearly constant displacement between the opposing surfaces. The ovoidal surfaces can be that of an egg shaped ovoid, an ellipse, or a sphere. The apparatus can have at least one ion inlet and an ion outlet where the outlet is on or as near as possible to a point on the defining axis in the outer electrode and the inlet or inlets are on, near, or symmetrically disposed about the defining axis of the ovoidal surfaces. Electrical contacts to the electrodes permit the application of an asymmetric waveform and a compensation voltage to at least one of the electrodes. The electrodes are positioned, stabilized, and insulated from each other by a base plate.

Abstract: An image sensor is provided. The image sensor comprises a readout circuitry, a first image sensing device, an interconnection, and a second image sensing device. The readout circuitry is disposed in a first substrate. The first image sensing device is disposed at one side of the readout circuitry of the first substrate. The interconnection is disposed over the first substrate and electrically connected to the readout circuitry. The second image sensing device is disposed over the interconnection.

Abstract: Provided are an image sensor and a method for manufacturing the same. The image sensor comprises: a readout circuitry, an interconnection, a contact plug, and an image sensing device. The readout circuitry is formed in a first substrate. The interconnection is electrically connected to the readout circuitry over the first substrate. The contact plug is formed over the interconnection, and includes an insulating layer at regions in an upper side thereof. The image sensing device is formed over the contact plug.

Abstract: The present invention concerns methods for evaluating the emotional response to stimuli, such as marketing communications. The present invention includes a method for correlating an emotional response to brain imaging data, a method identifying an emotional response to a stimulus, and a system for identifying an emotional response to a stimulus. The present invention can incorporate a psychological non-verbal measure, such as AdSAM®, and a neural-physiological measure, functional brain imaging, such as functional magnetic resonance imaging (fMRI), positron emission tomography (PET), or other functional brain imaging modality. For example, in marketing communication research, the emotional response data can be determined for such things as product concepts, advertising (concept and/or finished ads), product attributes, product benefits, brands, logos, tag lines, packaging, music, etc. The method of the invention can also be used to assess emotional response to different purchase options (e.g., retail vs.

Abstract: The present invention is related to a nucleic acid molecule and uses thereof. The nucleic acid molecule comprises a double-stranded structure, whereby the double-stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and said first stretch is at least partially complementary to a target nucleic acid, and whereby the second strand comprises a second stretch of contiguous nucleotides and said second stretch is at least partially complementary to the first stretch, whereby the first stretch comprises a nucleic acid sequence which is at least partially complementary to a nucleotide core sequence of the nucleic acid sequence according to SEQ ID NO:1 (NM_013355).

Abstract: Manzamine compounds have been discovered to decrease cell dissociation and cell migration associated with the metastatic potential of cancer cells and a restoration of cancer cell susceptibility to agents, such as TRAIL, which can induce apoptosis. Specifically, Manzamine A has a formerly unrecognized utility in both blocking tumor cell invasion and tumor metastasis as well in restoring cancer cell susceptibility to standard chemotherapeutic agents which induce apoptosis and, therefore, has utility in treating cancer.

Abstract: The present invention provides a method and apparatus for identifying a desired device handle in a computer system such as a personal computer running Linux™. The desired device handle is capable of facilitating or providing for interaction with a desired peripheral device, such as a USB™ device. The invention comprises providing a database containing information associating device handles with peripheral devices. A first portion of the database is scanned for information associated with the desired peripheral device. This information is used in determining a second portion of the database, which is scanned for information indicative of the desired device handle. The desired device handle is then identified.

Abstract: Disclosed are an image sensor and a method for manufacturing the same. The image sensor includes readout circuitry and an inter-layer dielectric layer on a first substrate, a metal line in the inter-layer dielectric layer and electrically connected with the readout circuitry, a plurality of contact plugs on the metal line, and an image sensing device on the contact plugs. The image sensing device is electrically connected to the metal line through the plurality of contact plugs. The method for manufacturing an image sensor includes forming a readout circuitry on a first substrate, forming an inter-layer dielectric layer on the first substrate, forming a metal line in the inter-layer dielectric layer such that the metal line is electrically connected with the readout circuitry, forming a plurality of contact plugs on the metal line per unit pixel, and forming an image sensing device on the plurality of contact plugs.

Abstract: The present patent application relates to novel combinations of a triazine derivative and of an insulin secretion stimulator.