Patents Represented by Attorney, Agent or Law Firm Sandy S. Zaradic
  • UL54.5 of Marek's disease virus (MDV)
    Patent number: 6299882
    Abstract: The present invention provides methods and reagents for inducing active immunity in animals. In particular, the present invention provides recombinant herpesviruses having foreign DNA that are capable of inducing immunity to the herpesvirus and/or the source of the foreign DNA. The present invention also provides mutant herpesviruses having portions of their genome deleted. Preferably, foreign DNA is introduced, or portions of the genome are deleted, in the UL54.5 open reading frame of avian herpesviruses or the UL43 open reading frame of Marek's disease virus.
    Type: Grant
    Filed: April 9, 1999
    Date of Patent: October 9, 2001
    Assignee: Schering Corporation
    Inventor: David E. Junker
  • Recombinant raccoonpox virus and uses thereof as a vaccine in mammalian and avian species
    Patent number: 6294176
    Abstract: The present invention provides a recombinant raccoonpox virus comprising a raccoonpox virus viral genome which contains a foreign DNA sequence inserted into a non-essential region within the HindIII “U” genomic region, the HindIII “M” genomic region, or HindIII “N” genomic region of the raccoonpox virus genome. The present invention provides a recombinant raccoonpox virus comprising a raccoonpox virus viral genome which contains a deletion in a raccoonpox virus host range gene of the viral genome. The present invention provides a homology vector for producing a recombinant raccoonpox virus by inserting a foreign DNA sequence into the raccoonpox virus genome. The present invention provides a recombinant raccoonpox virus which is useful as a vaccine in mammalian and avian species.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: September 25, 2001
    Assignee: Schering-Plough Veterinary Corp.
    Inventors: Mark D. Cochran, David E. Junker