Abstract: Azadirachta indica cell suspension culture was used for the biotransformation of dianabol to yield a metabolite 17?-hydroxy-17?-methyl-5?-androstan-3-one, which can also be synthesized, as a potent antiinflammatory agent.
Type:
Grant
Filed:
July 17, 2011
Date of Patent:
December 11, 2012
Inventors:
Saif Ullah, Saifullah Khan, Muhammed Ahmed Mesaik, Zaheerul Haq, Almas Jabeen, Sobia Ahsan Halim, Muhammad Iqbal Choudhary
Abstract: A method of manufacturing biological products in a single container from the growth of cells to purification of the product is performed in a flexible disposable bioreactor that uses only a compressed gas for mixing and gasification. A porous septum is used to create the gasification and mixing as well as to separate a chromatography media used to harvest and purify a biological product in the same container. The closed container can be used in any environment without the risk of contamination to the product or the risk of contamination of environment with the product. This allows large manufacturing of hazardous substances, drugs and vaccines anywhere at the lowest cost possible. Numerous applications can be found in counter-terrorism and biodefense operations as well in managing epidemic illnesses.
Abstract: Described here a composition comprising of alcoholic extracts of herbs RHIZOMA ZINGIBERIS RECENS, RHIZOMA PINELLIAE, FLOS CARTHAMI, RADIX REHMANNIAE, RADIX ANGELICAE SINESIS, RADIX PAENOIAE RUBRA, CACUMEN BIOTAE, SEMEN SESAMI NIGRUM, RADIX POLYGONI MULTIFLORI, FRUCTUS MORI combined with TINCTURE CAPSICUM, TINCTURE CANTHARIDINATE, and OLEUM RICINI for direct application to scalp for the treatment of all kinds of alopecia in humans. Alternately, the herbs listed here can be used individually.