Abstract: Methods for eliciting or enhancing immune responses to antigens, including tumor antigens, and/or DNA vaccines are provided. The methods employ polypeptides or nucleic acid compositions that contain at least a biologically active portion of a Leishmania braziliensis or Leishmania major homologue of the eukaryotic initiation factor 4A, or a variant thereof. Such polypeptides and compositions are useful for enhancing or eliciting a patient's cellular and/or humoral immune response, for instance within methods for treating tumors.
Abstract: This invention relates to a voltage comparator with an input for an analog signal and an output for a digital signal, comprising an inverter which has an input coupled to the comparator input and an output coupled to the comparator output, and comprising at least two MOS transistors coupled to each other, at least one of the two MOS transistors being of the floating gate type.
Type:
Grant
Filed:
October 29, 1997
Date of Patent:
January 11, 2000
Assignee:
STMicroelectronics S.r.l.
Inventors:
Alan Kramer, Roberto Canegallo, Mauro Chinosi, Giovanni Gozzini, Philip Leong, Marco Onorato, Pier Luigi Rolandi, Marco Sabatini
Abstract: A method and apparatus employs a production system-like rule based routine to process signals, such as reflectance signals produced from machine-readable symbols (e.g., bar code symbols). Relevant features data is extracted from each peak or valley in the signal, such as width, height, and relative size. The routine then uses the extracted data for each peak and valley with a set of rules to refine the reflectance signals. Under one or more iterations, the routine selects and resolves conflicting rules and applies resulting rules to process the signal. The processed signal can then be more readily decoded. The routine preferably processes a reflectance signal in portions, such as on a codeword-by-codeword basis. Under an alternative embodiment, a fuzzy inference engine provides sets of values for height, width and relative size. Therefrom rules are applied to determine a size of each peak and valley in the signal.
Abstract: The invention relates to a method of and an apparatus for controlling a plurality of mutually communicating actuators, each of the actuators having at least one signal sensor for determining the state of the actuator, with at least one control apparatus generating, in accordance with the state of at least one of the actuators, control signals used for driving controllers of the actuators. In order to avoid overheating of the individual actuators or the control apparatus in case of a large number of actuations by a user, it is provided to determine the temperature of the actuators and the control apparatus cooperating with the actuators and, in case a predetermined temperature threshold value is exceeded in an actuator or the control apparatus, to generate a control signal for non-driving the controllers of the actuators until the excessive temperature detected drops below the temperature threshold value by a defined temperature value.
Abstract: Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetics of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.
Type:
Grant
Filed:
April 30, 1997
Date of Patent:
January 11, 2000
Assignee:
Molecumetics, Ltd.
Inventors:
Michael Kahn, Masakatsu Eguchi, Hwa-Ok Kim
Abstract: An apparatus designed to damp external noises, allowing the user to sleep in noisy environments. More particularly, it relates to a pair of hearing-protecting ear covers that insulate the user's ears from external noises, ear covers that incorporate a headphone stereo for transmission of a time, smoke, fire and/or security alarms. The headphone stereo can also transmit music, peaceful sounds, or noise reducing frequencies. The sound producing circuitry is connect in parallel to the alarm system to allow alarm detection even when the user is listening to music or other sounds.
Abstract: A control signal compensation method is particularly intended for an analog/digital processing system provided with a control loop, including in turn a controller and a monitoring circuit. The method includes storing corrections made by the controller, fast processing such as corrections before transmitting the corrections throughout the control loop, and generating a compensation signal for the latency effects of the controller, by the use of a negative feedback loop provided at the monitoring circuit level.
Abstract: A single pull-up circuit is shared between a redundant row antifuse cell, and a redundant column antifuse cell. Additionally, a single selection circuit is shared between the two antifuse cells. A row selection signal supplied thereto selects the antifuse cell for the redundant row, while a column selection signal selects the antifuse cell for the redundant column. A small channel length transistor is employed within the latch circuit. As a result, the latch can quickly pull up a value when the antifuse cell is not blown, and quickly latch that value within the latch since an RC time constant of the latch is decreased. A pulsed pull-up signal having a very short duration is employed to enable the latch. Since the pulsed pull-up signal has a short duration, a high voltage supply V.sub.CC is provided through the latch and a blown antifuse cell to ground for only a short duration, thereby minimizing the possibility of such a low resistance current path from damaging the circuitry.
Abstract: A technique for sharing radio frequency spectrum between multiple satellite communication systems. A first and a second satellite communication system each contain a plurality of satellites in a plurality of non-geostationary (non-GSO) Earth orbits. Each of the plurality of non-GSOs has a predefined orbital plane. Within each orbital plane, satellites of the first and second satellite communication systems are alternating, such that each orbital plane contains satellites from each of the satellite systems. In this manner, it is possible to achieve satisfactory discrimination between satellites and Earth-based stations. The Earth-based station of each communication system will communicate with the closest satellite of its respective communication system.
Type:
Grant
Filed:
August 22, 1997
Date of Patent:
January 4, 2000
Assignee:
Teledesic LLC
Inventors:
Janet L. King, Richard C. Deininger, Kenneth C. Grzemski, Thomas L. Hayden, Mark A. Sturza
Abstract: An apparatus for releasably retaining a recreational board, such as a skateboard, snowboard or skis, is shown and described. In one embodiment, the apparatus has a main body with a front portion to which one or more straps is attached, and a rear portion to which a pair of opposing flaps is attached. The flaps extend from the main body such that the second flap overlaps the first flap when the two are wrapped in opposite directions around the recreational board. The overlapping surfaces of the two flaps are secured together to releasably retain the board. A connector is fixed to the second flap and extends from the rear portion of the carrier to the front portion of the carrier where it terminates in a grip. A force exerted on the grip subjects the connector to tension, causes the second flap to be separated from the first flap, and releases the board. In another embodiment, the connector extends through apertures in the front and rear portions of the main body.
Abstract: A synchronous clock generator is comprised of a delay-locked loop for producing a plurality of signals in response to an external clock signal. Each of the plurality of signals is delayed a predetermined period of time with respect to the external clock signal. A plurality of multiplexers is responsive to the plurality of signals for producing at least one clock signal in response to control signals input to the plurality of multiplexers. A clock driver is provided for driving the clock signal. A variable delay circuit is positioned to delay the external clock signal before input to the delay-locked loop. A compound feedback loop is responsive to certain of the plurality of signals for producing a control signal input to the variable delay circuit.
Abstract: An improved method and system for displaying original documents and translations and transcriptions thereof is provided. In a preferred embodiment, separate spatially aligned bitmaps are created and displayed in a main display and translation window. Image scrolling and movement of the translation window facilitate review and study of larger document pages. An overview feature with logical links to subject matter categories and a left to right mirroring feature are provided in preferred embodiments.
Type:
Grant
Filed:
October 21, 1996
Date of Patent:
January 4, 2000
Assignee:
Corbis Corporation
Inventors:
Mark B. Arend, Melanie B. Goldstein, Cecil J. Juanarena, Curtis G. Wong
Abstract: A programming method for a nonvolatile memory includes the steps of: a) determining a current value of the threshold voltage; b) acquiring a target value of the threshold voltage; c) calculating a first number of gate voltage pulses necessary to take the threshold voltage from the current value to the target value; d) applying a second number of consecutive voltage pulses to the gate terminal of the cell, the second number being correlated to the first number and having a uniformly increasing amplitude; e) then measuring a current value of the threshold voltage; and repeating steps c) to e) until a final threshold value is obtained.
Type:
Grant
Filed:
November 3, 1998
Date of Patent:
January 4, 2000
Assignee:
STMicroelectronics S.r.l.
Inventors:
Marco Pasotti, Pier Luigi Rolandi, Roberto Canegallo, Danilo Gerna, Ernestina Chioffi
Abstract: A coloring kit project for children producing magnetic frames for photographs and art work. The frame is composed of a flexible magnetic material suitable having designs for coloring or decoration which will adhere to a ferrous surface such as the door of a refrigerator. The invention focus is in particular on a magnetic frame kit composed of a plurality of printed outlines of frames with designs on a single sheet of flexible magnetic material and a plurality of decorative elements on a single sheet of flexible magnetic material which will magnetically adhere to either a magnetic frame or to a ferrous surface. Children will cut the magnetic frames and the decorative elements from the respective magnetic frame kit material sheets, will color the respective designs and use the resulting frame to display art work.
Abstract: The device is a one piece molded unity of resilient material consisting of a base (10) having upper and lower surfaces. The lower surface is generally flat. The upper surface is made non-planer by the presence of numerous irregularities, such as projections (12) (16) (18), formed as part of the unit during the fabrication process. A through hole (14) is provided for carrying purposes.
Abstract: A method for recovering at least one metal from an acidified waste water sludge by liquid-liquid extraction by providing an acidified waste water sludge containing ions of at least one metal and organic material, treating the waste water with an oxidizer to convert the organic material into a form that does not have an unfavorable effect on a subsequent liquid-liquid extraction, and subjecting the treated, acidified waste water sludge to a liquid-liquid extraction thereby obtaining an organic phase loaded with ions of said at least one metal, and subsequently recovering ions of said at least one metal from said organic phase.
Abstract: The present invention discloses carbohydrates and carbohydrate analogs that bind to epidermal growth factor (EGF) receptors. Methods of using such carbohydrates or analogs for a variety of uses related to the EGF receptor are also provided. In preferred aspects of the present invention, methods for killing or inhibiting the growth of tumor cells with increased EGF receptor activity are disclosed.
Abstract: A monolithic integrated multiple mode circuit having an output stage, a transfer gate, a control circuit arrangement, and a well contacting region where a well potential may be applied, the multiple mode circuit adapted to be controlled into an output stage mode or an input stage mode by means of control data.
Abstract: A telecommunications connector includes a body having a first end to mate with a mating connector and a second end having an aperture. A plurality of connector elements have a connection portion to make electrical contact with individual wires from wire cables. In an exemplary embodiment, the individual wires are in the form of twisted pair cables. The connector elements also include a terminating portion to make electrical contact with the mating connector, and an elongated intermediate portion coupling the corresponding connection and terminating portions. The elongated intermediate portion minimizes the overall surface area of the electrical contacts thereby reducing the capacitance between individual ones of the connector elements. In addition, the connector elements are mounted in a low dielectric constant material to further reduce capacitance between individual ones of the connector elements.
Type:
Grant
Filed:
November 18, 1997
Date of Patent:
December 28, 1999
Assignee:
Leviton Manufacturing Company, Inc.
Inventors:
Alan S. Lorenz, Franklin C. Marti, Clifford R. Curry
Abstract: A control and monitoring circuit for a power switch comprises a first portion (20) connected to this switch and fed with reference to a floating voltage (V.sub.F) of an electrode of this switch, a second portion (10) connected to circuits external to the switch and fed with reference to a fixed voltage, a coder (40) arranged on the side of the second portion and a suitable decoder (50) arranged on the side of the first portion.