Patents Represented by Attorney, Agent or Law Firm Serge Sira
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Patent number: 6746665Abstract: The present invention relates to a sun protection product which contains microparticles as the active agent, wherein the microparticles comprise water-insoluble linear polyglucan.Type: GrantFiled: February 25, 2002Date of Patent: June 8, 2004Assignee: Celanese Ventures GmbHInventors: Holger Bengs, Alfred Braunagel
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Patent number: 6747173Abstract: The invention relates to a method for the preparation of lactic acid and calcium sulphate, in which (a) an aqueous solution that contains lactate is reacted with sulphuric acid at a temperature that is essentially higher than the transition temperature of calcium sulphate dihydrate (CaSO4.2H2O), with the formation of a mixture that contains calcium sulphate hemihydrate and lactic acid, (b) the mixture from step (a) is subjected to at least one recrystallisation step at a temperature that is essentially lower than the transition temperature of calcium sulphate dihydrate, with the formation of a precipitate of calcium sulphate dihydrate and an aqueous solution of lactic acid, and (c) the precipitate of calcium sulphate dihydrate is separated off from the aqueous solution of lactic acid.Type: GrantFiled: August 29, 2002Date of Patent: June 8, 2004Assignee: Purac Biochem B.V.Inventors: Markus Gerkema, Aldwin Korevaar, Damien Michel Andre Camelot, Jan Van Breugel, Geert-Jan Witkamp, Agusti CerdàBaro
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Patent number: 6720044Abstract: The invention relates to pharmaceutical closures for containers made of flexible polyolefinic materials which are suitable to be filled with parentally administrable fluids prior to their sealing and sterilization. The polyolefinic closures have an excellent resealing capacity after being penetrated by a piercing device for establishing fluid communication with the container, even after multiple entries into the container.Type: GrantFiled: February 20, 1998Date of Patent: April 13, 2004Assignee: Pharmacia ABInventors: Gunnar Andersson, Des Mulligan
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Patent number: 6719815Abstract: The invention relates to a fuel composition which comprises a diesel fuel, a C1-C4 alkyl ester of an &agr;-hydroxymonocarboxylic acid and, if appropriate, a C1-C4 alcohol. The diesel fuel is either obtained from petroleum or from a petroleum fraction, such as middle distillate, or is obtained by conversion of material of biological origin (so-called biodiesel). The fuel composition preferably contains from 3 to 6% by weight of C1-C4 alkyl ester, calculated on the basis of the total weight of the composition.Type: GrantFiled: September 18, 2002Date of Patent: April 13, 2004Assignee: Purac Biochem B.V.Inventors: Gerrit Leendert Nanninga, Jan Van Breugel
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Patent number: 6713137Abstract: The present invention relates to a flexible polyolefin multilayered film for preparation of medical containers by self sealing, comprising at least a first outer layer and a second layer, each of the layers consisting essentially only of one or more polypropylene based polymers selected from the group consisting of polypropylene homopolymers, polypropylene copolymers having randomly distribute ethylene units and mixtures of said homopolymers and said copolymers, wherein said second layer has a melting point in the range between 120° C. and 150°, said first outer layer has a lower flexibility and a higher melting point than said second layer, and said second comprises a polypropylene polyethylene copolymer with a higher amount of ethylene units than said outer layer. The present invention also relates to medical containers made of or comprising the above film.Type: GrantFiled: November 23, 1999Date of Patent: March 30, 2004Assignee: Fresenius Kabi ABInventors: Gunnar Andersson, Vittorio Sala
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Patent number: 6696563Abstract: The invention relates to a production method of &agr;-amylase resistant polysaccharides with high RS content, comprising the following steps: a) producing a paste of water-insoluble poly-(1,4-&agr;-D-glucan) and water; b) heating the paste; c) cooling off and retrogradation of the past at a temperature that is lower than the temperature of the heated paste and d) optionally drying the resulting product.Type: GrantFiled: December 21, 2000Date of Patent: February 24, 2004Assignee: Celanese Ventures GmbHInventors: Holger Bengs, Gisela Jacobasch, Detlef Schmiedl, Jörg Riesmeier, Martin Quanz, Michael Bäuerlein, Nicholas Provart
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Patent number: 6676956Abstract: The invention relates to an oil-in-water emulsion comprising, as an active ingredient, &agr;-tocopherol or the stereoisomers thereof and comprising, as an emulsifier, phospholipids. The inventive emulsion is used in order to attain a protective action against damages to human organs resulting from peroxidation. The emulsion contains a &agr;-tocopherol content, with regard to action, of 1.48 g/l to 30 g/l RRR-g(a)-tocopherol, 0-25 g/l of an oil which is compatible with I.V. administration, and 0.25 g/l to 3 g/l of a phospholipid. The emulsion is preferably administered as an infusion and is especially used to reduce damages resulting from peroxidation due to ischemia and /or reperfusion and, among other things, during an organ transplantation.Type: GrantFiled: October 1, 2001Date of Patent: January 13, 2004Assignee: Fresenius Kabi Austria GmbHInventors: Udo Eggenreich, Norbert Feichtinger, Gerald Hofer, Karin Schaupp, Klaus Sommermeyer, Anneliese Wurm, Eckhard Nagel, Andreas Meyer zu Vilsendorf
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Patent number: 6634076Abstract: The invention relates to an article of manufacture comprising a partial or complete tubular primary part defining a tube axis and having an at least partially curved circumferential wall at least partially encircling the axis; said wall comprising a joint edge, defining a) a joint line along said edge on said wall, b) a joint plane drawn to contain said joint line, c) a joining direction having at least a direction component perpendicular to said joint line and said joint plane, d) a locking plane at least partially at the surface or within a section through said wall in which both said joint line and said joining direction lies and e) a normal direction being perpendicular to said joint plane; and at least one locking structure, the improvement comprising that the locking structure includes at least one positive or negative hook structure in said locking plane, extending in the joining direction away from the joint line and having an undercut in the locking plane and that the hook structure is exposed from aType: GrantFiled: May 3, 2002Date of Patent: October 21, 2003Assignee: Pharmacia ABInventors: Birger Hjertman, Rudolf Cseke
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Patent number: 6627443Abstract: The present invention relates to new color compositions which are especially suitable to be used in oxygen indicators. The compositions comprise iron(II), an agent containing pyrogallol entities and an organic acid.Type: GrantFiled: April 27, 2000Date of Patent: September 30, 2003Assignee: Fresenius Kabi ABInventors: Åke Stenholm, Lars Karlsson, Anders Löfgren, Bo Nystrom, Otto Skolling
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Patent number: 6579899Abstract: A method of treating stress in a patient showing stress related symptoms is disclosed, where the method comprises administering to the patient an effective amount of a serotoninergic drug or prodrug. Specific examples of such drugs are described, and include, among others, tryptophan or 5-hydroxytryptophan, or their salts.Type: GrantFiled: January 27, 2000Date of Patent: June 17, 2003Assignee: Massachusetts Institute of TechnologyInventors: Judith J. Wurtman, Richard J. Wurtman
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Patent number: 6548075Abstract: The present invention relates to a topical preparation containing spherical microparticles as the essential component, wherein the microparticles comprise water-insoluble linear polyglucan.Type: GrantFiled: November 14, 2001Date of Patent: April 15, 2003Assignee: Celanese Ventures GmbHInventors: Holger Bengs, Arnold Schneller, Jürgen Grande, Silke Schuth, Gitte Böhm, Alfred Braunagel
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Patent number: 6528165Abstract: The present invention provides novel encapsulation compositions and methods. In particular, the invention relates to fluorescent capsule compositions, which consists of a layer of a polymer shell enclosing one or more fluorescent materials such as fluorescent microspheres and which are capable of emitting at least two distinct fluorescent signals. Also provided are methods for their preparation. The compositions and methods of this invention are useful in a variety of applications, including preparation of multiplexed arrays for industrial, chemical, immunological, and genetic manipulation and analysis especially as related but not limited to flow cytometry.Type: GrantFiled: March 25, 2002Date of Patent: March 4, 2003Assignee: Luminex CorporationInventor: Don J. Chandler
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Patent number: 6524793Abstract: A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry. Flow cytometric measurements are used to classify, in real-time, beads within an exposed beadset and textual explanations, based on the accumulated data obtained during real-time analysis, are generated for the user. The inventive technology enables the simultaneous, and automated, detection and interpretation of multiple biomolecules or DNA sequences in real-time while also reducing the cost of performing diagnostic and genetic assays.Type: GrantFiled: June 18, 1999Date of Patent: February 25, 2003Assignee: Luminex CorporationInventors: Van S. Chandler, R. Jerrold Fulton, Mark B. Chandler
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Patent number: RE38566Abstract: A composition is disclosed for alleviating or managing symptoms associated with premenstrual syndrome “PMS” comprising an effective amount of an aqueous mixture of water and a rapidly digestible carbohydrate blend. The aqueous mixture is essentially free of protein and is characterized by a certain pH and ratio of water to carbohydrate blend. Methods of use of the composition for alleviating or managing symptoms associated with PMS are also disclosed.Type: GrantFiled: September 4, 1998Date of Patent: August 17, 2004Assignee: Walden Laboratories, Inc.Inventors: Judith J. Wurtman, Jeff L. Shear, Alvin Kershman