Patents Represented by Attorney, Agent or Law Firm Sheela Mohan-Peterson
  • Interleukin-10 antibodies
    Patent number: 8226947
    Abstract: The methods and compositions provided herein relate generally to IL-10 specific antibodies and uses thereof. More specifically, compositions of humanized IL-10 specific antibodies and methods to use such antibodies in modulating the biological activity of IL-10, particularly in autoimmune disorders and pathogen-mediated immunopathology.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: July 24, 2012
    Assignee: Schering Corporation
    Inventor: Leonard G. Presta
  • Anti-MDL-1 antibodies
    Patent number: 8153134
    Abstract: Antibodies to human MDL-1 are provided, as well as uses thereof, e.g., in treatment of immune disorders, in particular, infectious diseases and sepsis.
    Type: Grant
    Filed: April 21, 2008
    Date of Patent: April 10, 2012
    Assignee: Schering Corporation
    Inventors: Michael E. Bigler, Paul G. Heyworth, Joseph H. Phillips, Leonard G. Presta
  • Nucleic acid encoding TNFx protein
    Patent number: 8148507
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: April 3, 2012
    Assignee: Schering Corporation
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • Mammalian genes; related reagents and methods
    Patent number: 7893211
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: February 22, 2011
    Assignee: Schering Corporation
    Inventor: Daniel M. Gorman
  • DIRS1 polypeptides
    Patent number: 7812126
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: October 12, 2010
    Assignee: Schering Corporation
    Inventors: Christi L. Parham, Kevin W. Moore, Nicholas J. Murgolo, J. Fernando Bazan
  • Methods of treating wounds using IL-23
    Patent number: 7332156
    Abstract: Provided are methods of treatment for skin disorders. In particular, treatment, the skin disorders are generally inflammatory skin disorders, including improper wound healing. Provided are methods of using of a cytokine molecule.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: February 19, 2008
    Assignee: Schering Corporation
    Inventors: Edward P. Bowman, Shi-Juan Chen, Daniel J. Cua, Jason R. Chan
  • Uses of IL-23 agonists and antagonists; related reagents
    Patent number: 7282204
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for modulating activity of a cytokine molecule and its receptor.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: October 16, 2007
    Assignee: Schering Corporation
    Inventors: Martin Oft, Terrill K. McClanahan
  • Cytokine receptor
    Patent number: 7071308
    Abstract: Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: July 4, 2006
    Assignee: Schering Corporation
    Inventors: Pedro A. Reche-Gallardo, Vassilli Soumelis, Yong-Jun Liu, Rene de Waal Malefyt, J. Fernando Bazan, Robert A. Kastelein
  • Population of interferon producing cells
    Patent number: 6913924
    Abstract: Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: July 5, 2005
    Assignee: Schering Corporation
    Inventors: Bianca Blom, Yong-Jun Liu
  • Method for detecting IL-B30 polynucleotides
    Patent number: 6835825
    Abstract: The invention provided herein relates generally to purified genes encoding mammalian cytokines as well as reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules. In particular, the novel cytokine, IL-B30, is provided herein as well as methods and kits for the detection of the expression of IL-B30 polynucleotides.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: December 28, 2004
    Assignee: Schering Corporation
    Inventor: J. Fernando Bazan
  • Mammalian cytokine complexes
    Patent number: 6800460
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: March 9, 2000
    Date of Patent: October 5, 2004
    Assignee: Schering Corporation
    Inventors: Birgit Oppmann, Jacqueline C. Timans, Robert A. Kastelein, J. Fernando Bazan
  • AK155 antibodies and binding fragments thereof
    Patent number: 6797813
    Abstract: Purified genes encoding a cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using these reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: September 28, 2004
    Assignee: Schering Corporation
    Inventors: Rene de Waal Malefyt, Helmut Flickensher, Bernhard Fleckenstein, Andrea Knappe
  • IL-23 receptor binding compositions
    Patent number: 6756481
    Abstract: Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: June 29, 2004
    Assignee: Schering Corporation
    Inventors: Madaline Chirica, Robert A. Kastelein, Kevin W. Moore, Christi L. Parham
  • 7 transmembrane receptor family member BLRX
    Patent number: 6737252
    Abstract: Novel chemokines and 7 transmembrane receptors from mammals, reagents related thereto, including purified proteins, specific antibodies, and nucleic acids encoding the chemokines and receptors are disclosed. Methods of using the chemokines, receptors, reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: May 18, 2004
    Assignees: Schering Corporation, Canji, Inc.
    Inventors: Joseph A. Hedrick, Bernhard Homey, Alain Vicari, Monica L. Zepeda, Albert Zlotnik
  • Antibodies that bind chemokine teck
    Patent number: 6723520
    Abstract: Novel chemokines from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said chemokines. Chemokine receptors are also provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: January 3, 2002
    Date of Patent: April 20, 2004
    Assignee: Schering Corporation
    Inventors: Wei Wang, Kurt C. Gish, Thomas J. Schall, Alain Vicari, Albert Zlotnik
  • Nucleic acids encoding CTLA-8; and related reagents
    Patent number: 6706870
    Abstract: CTLA-8 antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: March 16, 2004
    Assignees: Inserm, Institut National de la Sante et de la Recherche Medicale, Schering Corporation
    Inventors: Pierre Golstein, Eric Rouvier, Francois Fossiez, Serge J. E. Lebecque, Odile Djossou, Jacques Banchereau
  • Nucleic acids encoding mammalian interleukin-1&zgr;, related reagents and methods
    Patent number: 6680380
    Abstract: Nucleic acids encoding mammalian, e.g., primate, IL-1&zgr;, purified IL-1&zgr; polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: January 20, 2004
    Assignee: Schering Corporation
    Inventor: Jacqueline C. Timans
  • Dendritic cells; methods
    Patent number: 6660523
    Abstract: Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: December 9, 2003
    Assignee: Schering Corporation
    Inventors: Bianca Blom, Yong-Jun Liu
  • Purified mammalian CTLA-8 antigens and related reagents
    Patent number: 6562333
    Abstract: CTLA-8 antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: May 13, 2003
    Assignee: Schering Corporation
    Inventors: Pierre Golstein, Eric Rouvier, François Fossiez, Serge J. E. Lebecque
  • IL-17-like cytokine binding compounds and antibodies
    Patent number: 6562578
    Abstract: IL-17-like cytokines from mammals, reagents and diagnostic kits related thereto including purified proteins, specific antibodies, and nucleic acids are provided. Methods of using the reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: May 13, 2003
    Assignee: Schering Corporation
    Inventors: Daniel M. Gorman, J. Fernando Bazan, Robert A. Kastelein