Abstract: This invention provides a process for conducting Stille coupling reactions. The processes of the present invention make use of N-heterocyclic carbenes as ancillary ligands in Stille couplings of aryl halides.
Type:
Grant
Filed:
February 22, 2000
Date of Patent:
March 26, 2002
Assignee:
University of New Orleans Research & Technology
Foundation
Inventors:
Steven P. Nolan, Jinkun Huang, Mark L. Trudell, Chunming Zhang
Abstract: The use of one or several alkyl hydrogen fumarates of the general formula
wherein R is a C1-5 alkyl, optionally in admixture with dialkyl fumarate of the formula
and optionally customary pharmaceutical excipients and carriers for preparing a pharmaceutical composition in the form of micro-tablets or micro-pellets for treating psoriasis, psoriatic arthritis, neurodermatitis and enteritis regionalis Crohn.