Patents Represented by Attorney, Agent or Law Firm Steven T. Trinker
  • Patent number: 5091176
    Abstract: Biocompatible polymers derived from isocyanate-capped high molecular weight triols and higher polyols are covalently linked to drugs. These polymer-modified drugs have one or more of the following advantages over the unmodified drug: reduction of immunogenicity of the drug, increased circulating half-life of the drug due to longer residence time in circulation, ability to administer multiple drugs together, and enhanced potency of the drug.
    Type: Grant
    Filed: April 24, 1990
    Date of Patent: February 25, 1992
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: James A. Braatz, Aaron H. Heifetz
  • Patent number: 5088576
    Abstract: A mass and spring system for soundproofing, particularly in vehicles, comprises a bending-soft heavy plastic layer as the mass and a soft layer as the spring, which is applied to the sound radiating surface or wall and which is a gel of 10 to 50% by weight of an organic polymer or silicone polymer and 50 to 90% by weight of a plasticizer compatible therewith, which at room temperature has a modulus of elasticity E'.ltoreq.5.times.10.sup.5 Pa and an internal loss factor d.gtoreq.0.5.
    Type: Grant
    Filed: July 12, 1989
    Date of Patent: February 18, 1992
    Assignee: E.A.P. Akustik GmbH
    Inventors: Hans-Hermann Potthoff, Ingolf Scheffler, Klaus Ruch, Rainer Joesel
  • Patent number: 5053228
    Abstract: The drug carrier of this invention provides a temperature-sensitive polymer chemically bonded to a drug. The drug carrier is capable of releasing a drug continuously in the body. The drug carrier is a liquid when administered and becomes solid in the body, in which state it is capable of releasing a drug continuously. The drug carrier has a lower LCST than human body temperature.
    Type: Grant
    Filed: July 13, 1990
    Date of Patent: October 1, 1991
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Yuichi Mori, Toshiya Sakai
  • Patent number: 5002872
    Abstract: Disclosed herein is an enzymatic process to bind two amino acids in the presence of a water-miscible solvent. Preferably the amino acids are precursors of aspartame and a preferred solvent is acetonitrile.
    Type: Grant
    Filed: May 10, 1989
    Date of Patent: March 26, 1991
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Akiva T. Gross
  • Patent number: 4970001
    Abstract: Improvement in cross-flow membrane filtration. Chitosan is admixed with an aqueous dispersion of colloids or finely divided solids to flocculate the solids. The chitosan-flocculated liquid is then filtered on a membrane by cross-flow under pressure. A layer of chitosan-containing flocculant material deposits on the membrane and provides superior flux performance as compared to certain commerical flocculants.
    Type: Grant
    Filed: May 5, 1989
    Date of Patent: November 13, 1990
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: John J. Sheehan
  • Patent number: 4966846
    Abstract: Neutral protease genes from Vibrio proteolyticus or Bacillus can be cloned and expressed in gram-negative microorganisms, such as E. coli or Serratia. The functional neutral protease enzyme is expressed.
    Type: Grant
    Filed: November 19, 1987
    Date of Patent: October 30, 1990
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Alan H. Deutch, Victor A. David
  • Patent number: 4950715
    Abstract: Heat- and moisture hardening, one component polyurethane sealants and adhesives based on telechelic isocyanate prepolymers made from aromatic diisoyanates in stoichiometric excess and polyols comprise (a) a catalyst for moisture-hardening and (b) a blocked cross-linking agent activatable by heating, particularly a methylene dianiline/sodium chloride complex compound or a polyamino- or hydroxy-functional compound in microencapsulated form.
    Type: Grant
    Filed: December 16, 1988
    Date of Patent: August 21, 1990
    Assignee: Teroson GmbH
    Inventors: Edward W. Duck, Ingolf Scheffler, Michael Hirthammer, Norman Blank
  • Patent number: 4895621
    Abstract: A water soluble thermosetting resin useful as a promoter for paper sizing is described. Polyallylamine or a modified polyallyamine is reacted with epichlorohydrin and/or formaldehyde. The formaldehyde may be reacted with the polyallylamine in the presence of dicyandiamide, urea or an ammonium salt or mixtures thereof.
    Type: Grant
    Filed: November 18, 1986
    Date of Patent: January 23, 1990
    Assignee: W. R. Grace AB
    Inventor: Thord G. Hassler
  • Patent number: 4892585
    Abstract: A process for producing polyurethane foam articles is described, in which the article is produced in the conventional manner by foaming in a mould and a release agent is applied to the mould surface prior to filling with the foam-producing components. According to the invention, a solvent-free, aqueous release agent is used in combination with one or more alkali metal and/or ammonium salts of higher fatty acids and one or more higher alcohols and the combination is applied in the hot state, preferably at a temperature of at least 75.degree. C. to the mould surface. In addition, an additive is described, which is suitable for performing the process according to the invention and contains one or more alkali metal and/or ammonium salts of higher fatty acids, one or more higher alcohols and otherwise water.
    Type: Grant
    Filed: October 17, 1988
    Date of Patent: January 9, 1990
    Assignee: Grace Service Chemicals GmbH
    Inventors: Wolfgang Fischer, Thomas Hattich, William Krug, Gerhard Schuster
  • Patent number: 4879306
    Abstract: A composition killing or inhibiting the growth of microorganisms is described and which contains a mixture of 4,5-dichloro-1,2-dithiol-3-one and dibromonitrilopropionamide. The combination leads to a marked synergistic action of the two active substance components in the control of microorganisms. The composition is suitable for use in a large number of industrial systems.
    Type: Grant
    Filed: September 27, 1985
    Date of Patent: November 7, 1989
    Assignee: Grace Service Chemicals GmbH
    Inventors: Wolf-Dieter Henkels, Marion Balzer
  • Patent number: 4875436
    Abstract: There is provided a waste heat recovery system characterized by a boiler assembly including a heat recovery steam generator through which exhaust gas is flowed. The boiler assembly includes a high temperature steam tube heat exchanger, or superheater, and at a location downstream therefrom a water tube boiler. An ammonia gas injector is utilized for injecting ammonia into the exhaust gas stream which injector is located upstream of the superheater and water tube boiler. Finally, there is provided a low temperature selective catalytic reduction unit located downstream of the low temperature water tube boiler or evaporator. This arrangement simplifies retrofitting of existing heat recovery systems.
    Type: Grant
    Filed: May 23, 1988
    Date of Patent: October 24, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Edward M. Smith, Richard C. Cornelison
  • Patent number: 4873359
    Abstract: Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspartame or derivative by enzymatic coupling of phenylserine or derivative with aspartic acid or derivative. Hydrogenation of the coupled product to give as final product aspartame or analog with related processes and products.
    Type: Grant
    Filed: October 1, 1987
    Date of Patent: October 10, 1989
    Assignee: W. R. Grace & Co. - Conn.
    Inventors: Alan B. Chmurny, Akiva T. Gross, Robert J. Kupper, Rowena L. Roberts
  • Patent number: 4869738
    Abstract: A regenerable particulate trap for continuously separating particulates from, for example, the exhaust gas from a diesel engine, is characterized by a rotatable trap member mounted for rotation in the exhaust gas stream. Disposed over the face of the rotatable trap member on the upstream side is an enclosed, stationary chamber which isolates a portion of the rotatable trap member from the exhaust gas stream and directs a regenerating fluid through the rotating trap member, co-currently to the exhaust gas stream, to continuously remove the trapped particles by, e.g. burning in an oxygen-containing gas.
    Type: Grant
    Filed: August 26, 1987
    Date of Patent: September 26, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: William R. Alcorn, Wesley P. Bullock, Edward M. Smith, William A. Whittenberger
  • Patent number: 4865983
    Abstract: Cleaning compositions containing an extracellular protease produced by a microorganism of the genus Vibrio are provided. Such enzymes are characterized by a high proteolytic activity, stability over wide pH and tmperature ranges and excellent stability to oxidizing agents, including a unique stability to chlorine bleaches, and are well-suited for formulation into laundry detergents, automatic dishwasher detergents, laundry bleaches, pre-soaks, as well as other types of cleaning compositions.
    Type: Grant
    Filed: December 4, 1987
    Date of Patent: September 12, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Donald R. Durham
  • Patent number: 4849274
    Abstract: There is provided an improved honeycomb type gas conduit characterized by alternating noncorrugated aluminized ferrous metal foil and corrugated metal foil sheets in contact with each other at the apices or crests of the corrugation. The conduit has an inlet and an outlet for the gas and the honeycomb structure from 20 to 200 cells per square inch. The axes of the cells are parallel throughout their length. A hardened ceramic lip is provided at the leading edge of the cells, and preferably at the leading and trailing edges. When hardened by curing, e.g., with high temperature, the ceramic applied as a slip, forms fillets at the nips between the corrugations and the flat foil sheets, and cements the two together very tightly.
    Type: Grant
    Filed: September 28, 1987
    Date of Patent: July 18, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Richard C. Cornelison
  • Patent number: 4847315
    Abstract: A water-soluble, thermosetting resin comprising units derived from tris(2-aminoethyl)amine, and preferably units derived from dicyandiamide and/or epichlorohydrin, is useful as an accelerator in paper sizing, e.g. using an alkyl ketene dimer.
    Type: Grant
    Filed: June 3, 1987
    Date of Patent: July 11, 1989
    Assignee: W. R. Grace AB
    Inventor: Thord G. G. Hassler
  • Patent number: 4838067
    Abstract: There is provided a method for inhibiting corrosion at elevated temperatures of a nonnesting accordion folded or wound corrugated thin metal strip. The strip is corrugated with a longitudinally running series of peaks and valleys by passing the strip through a set of corrugating gears, each of the corrugations including one longitudinally extending displacement deviating from and returning to an imaginary line extending between the longitudinal marginal edges of the strip. The corrugations are characterized further in that the deviation extends in the direction of movement of the strip through the corrugating gears and is first to enter and exit from such gears. This places the maximum of the deviation in compression which has been found to minimize corrosion, e.g., from the pollutants contained in the exhaust from an internal combustion engine.
    Type: Grant
    Filed: May 18, 1987
    Date of Patent: June 13, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Richard C. Cornelison
  • Patent number: 4831009
    Abstract: There is provided a washcoat for applying a catalyst coating to a catalyst support. The washout includes alumina and a catalyst metal from the platinum group. Thus, the alumina and the catalyst metal are applied to the support in a single coating. The invention also includes a method of making the washcoat. The washcoat made by the present invention is economical to apply, and it has the additional advantage that it adheres tightly to a metal support.
    Type: Grant
    Filed: May 2, 1988
    Date of Patent: May 16, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: William B. Retallick
  • Patent number: 4829655
    Abstract: This invention relates to catalyst supports, such as are used in catalytic converters for vehicles, and in other applications, such as diesel particulate traps. The invention discloses a novel composition for a catalyst support, and a method of making it. The support includes a base material, such as a stainless steel. If the base material is a metal, it can be rolled down to the thickness of a foil and then coated with a layer of aluminum. The coating is done by a vapor deposition technique, so that the aluminum coating is thin and substantially uniform. The base material can be almost any substance capable of withstanding the high temperatures expected in the catalytic converter or other application. Because the material is already of foil thickness when it is coated, it is not necessary to select a material which is capable of being rolled down after being coated with aluminum. Thus, the invention makes it possible to use a much wider variety of materials than have been used in the prior art.
    Type: Grant
    Filed: March 24, 1987
    Date of Patent: May 16, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Richard C. Cornelison, William B. Retallick
  • Patent number: 4823583
    Abstract: There is provided a particulate trap for reducing the amount of particulates emanating from the exhaust of an internal combustion engine. The device utilizes a wound or accordion folded corrugated metal strip. The corrugations are characterized by a plurality of isolated projecting geometric configurations, such as a V-shaped chevrons spaced along a straight line extending between the parallel marginal edges of the thin metal strip. The apices of the metal strip pass through the corrugating rolls to place such apices in compression rather than in tension. These devices are not subject to nesting and are effective to remove diesel exhaust particulates.
    Type: Grant
    Filed: August 10, 1988
    Date of Patent: April 25, 1989
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Wesley Bullock, William A. Whittenberger