Abstract: Pharmaceutical compositions for controlling, by topical administration, localized bleeding in a patient, the composition comprising active PAI-1 protein in an amount effective to control the localized bleeding when topically administered, and a vehicle suitable for the topical administration, as well as methods and kits employing the same, are disclosed.
Type:
Grant
Filed:
January 10, 1992
Date of Patent:
October 19, 1993
Assignee:
The Du Pont Merck Pharmaceutical Company
Inventors:
Adrienne L. Racanelli, Thomas M. Reilly
Abstract: Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.
Type:
Grant
Filed:
April 6, 1988
Date of Patent:
February 16, 1993
Assignee:
Du Pont Merck Pharmaceutical Company
Inventors:
Charles A. Kettner, Ashokkumar B. Shenvi
Abstract: Novel calcium dialuminate/hexaluminate ceramic structures in the form of blends, laminates and composites, and processes for making these structures are disclosed. The ceramics of the invention exhibit relatively lower levels of thermal expansion, high strengths, and good thermal shock resistance over wide temperature ranges.
Abstract: An improved multi-boom field spraying apparatus designed to spray in a sequential manner one or more of a plurality of liquids to a selected spray zone among a number of spray zones is described. The apparatus contains a novel spray, agitate air and rinse system. A novel spray boom and vessel apparatus are also described.
Abstract: Free radical polymerization processes employing cobalt(II) chelates of vicinal iminohydroxyimino compounds, dihydroxyimino compounds, diazadihydroxyiminodialkyldecadienes and diazadihydroxyiminodialkylundecadienes as catalytic chain transfer agents for controlling the molecular weight of the homopolymers and copolymers produced.