Patents Represented by Attorney Suzanne Miller

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  • Intermediates for preparing peptide boronic acid inhibitors of trypsin-like proteases
    Patent number: 5250720
    Abstract: Intermediates for the preparation of Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: October 5, 1993
    Assignee: The Dupont Merck Pharmaceutical Company
    Inventors: Charles A. Kettner, Ashokkumar B. Shenvi
  • Peptide boronic acid inhibitors of trypsin-like proteases
    Patent number: 5242904
    Abstract: Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: September 7, 1993
    Assignee: The Dupont Merck Pharmaceutical Company
    Inventors: Charles A. Kettner, Ashokkumar B. Shenvi