Abstract: The methods of the invention can be used to treat mycobacterial infections, or any disease or disorder that is caused by (or aggravated by) an intracellular pathogen. Accordingly, the invention features methods for treating a subject who has a disorder that is associated with an intracellular pathogen by administering, to a subject, a molecular conjugate that includes a photosensitizer (a term used herein to refer to a light activatable compound) and a targeting moiety, the targeting moiety being capable of targeting the conjugate to the intracellular pathogen.

Abstract: Disclosed and claimed is bone or bone tissue supplemented with a therapeutically effective compound and methods for supplementing bone or bone tissue with the therapeutically effective compound.

Abstract: Disclosed and claimed is a laminar structure. The laminar structure has multiple layers. Each layer has tissue and vasculature. The layers are abjacent. The vasculature is in three dimensions through the structure. The structure has connections for flow into and out of the vasculature. The structure can be implanted directly by connecting blood vessels to flow into and out of the vasculature.