Patents Represented by Attorney, Agent or Law Firm Thomas P. McBride
  • Patent number: 7939708
    Abstract: Maize markers useful for genotyping and association studies, e.g. association with oil content QTLs in populations derived from the Illinois High Oil and Illinois Low Oil maize lines. Primers and hybridization probes for Taqman™ assays are provided for 488 SNP markers in 484 loci.
    Type: Grant
    Filed: July 22, 2004
    Date of Patent: May 10, 2011
    Assignee: Monsanto Technology LLC
    Inventor: Cathy C. Laurie
  • Patent number: 7423203
    Abstract: A method of changing the activity of hexokinases in a plant sink comprising introducing into the plant a gene encoding a fungal hexokinase. In the method, the gene is expressed in the plant seed tissue to produce the protein, thereby changing characteristics of hexokinase activity in the seed of the plant.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: September 9, 2008
    Assignee: Monsanto Technology, LLC
    Inventors: Nordine Cheikh, Dane Fisher, Rebecca Thompson
  • Patent number: 6825400
    Abstract: The present invention relates to corn plant PV-ZMGT32 (nk603 ) having a transformation event that produces glyphosate tolerance. The invention also relates to progeny corn plants having this event.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: November 30, 2004
    Assignee: Monsanto Technology LLC
    Inventors: Carl Frederick Behr, Gregory R. Heck, Catherine Hironaka Hironaka, Jinsong You
  • Patent number: 6815580
    Abstract: Sedoheptulose 1,7-bisphosphatase (SBPase) is an enzyme catalyzing the reaction converting sedoheptulose 1,7-bisphosphate into sedoheptulose 7-phosphate. This enzyme is located in the chloroplast in leaves and stems. Overexpression of the Chlorella sorokiniana SBpase in transgenic plants is provided to improve plant yield by increasing leaf starch biosynthetic ability in particular and sucrose production in general.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: November 9, 2004
    Assignee: Monsanto Technology LLC
    Inventors: Philip W. Miller, Robin L. Staub
  • Patent number: 6812379
    Abstract: Constructs and methods are provided for expressing peptides derived from eukaryotic organisms in plant plastids. Constructs have a promoter functional in a plant plastid, a DNA sequence encoding a peptide derived from an eukaryotic organism and a transcription termination region. Other elements include a selectable marker for selection of plant cells comprising a plastid expressing the marker and DNA regions of homology to the genome of the plastid and optionally a ribosome binding site joined to the promoter. By methods using such constructs high levels of eukaryotic peptides, such as mammalian proteins, are produced in a plant cell by growing plant cells under conditions whereby the DNA encoding sequences are expressed to produce eukaryotic peptide in said plastid.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: November 2, 2004
    Assignee: Calgene LLC
    Inventor: Jeffrey M. Staub
  • Patent number: 6781033
    Abstract: Novel compositions and methods useful for genetic engineering of plant cells to provide a method of producing plastid transformed plants are provided in the instant invention. In particular, the present invention provides methods for obtaining plastid transformed plants on medium containing plastid lethal compounds.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: August 24, 2004
    Assignee: Monsanto Technology LLC
    Inventors: Jeffrey M Staub, Guangning Ye, Debra L. Broyles
  • Patent number: 6723837
    Abstract: This invention relates to the field of biotechnology, particularly as it pertains to a nucleic acid molecule encoding a protein associated with sterol and phytosterol synthesis and metabolism. The invention also relates to methods of detection using the nucleic acid molecule, or the encoded protein as a probe or in a microarray.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: April 20, 2004
    Assignee: Monsanto Technology LLC
    Inventors: Balasulojini Karunanandaa, Jaehyuk Yu, Ganesh Kishore
  • Patent number: 6716474
    Abstract: Fructose-1,6-bisphosphate aldolase (FDA) is an enzyme reversibly catalyzing the reaction converting triosephosphate into fructose-1,6-bisphosphate. In the leaf, this enzyme is located in the chloroplast (starch synthesis) and the cytosol (sucrose biosynthesis). Transgenic plants were generated that express the E. coli fda gene in the chloroplast to improve plant yield by increasing leaf starch biosynthetic ability in particular and sucrose production in general. Leaves from plants expressing the fda transgene showed a significantly higher starch accumulation, as compared to control plants expressing the null vector, particularly early in the photoperiod, but had lower leaf sucrose. Transgenic plants also had a significantly higher root mass. Furthermore, transgenic potatoes expressing fda exhibited improved uniformity of solids.
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: April 6, 2004
    Assignee: Monsanto Technology LLC
    Inventors: Gerard F. Barry, Nordine Cheikh, Ganesh M. Kishore
  • Patent number: 6706950
    Abstract: This invention relates to sequences encoding &bgr;-ketoacyl-ACP synthase (KAS) and methods of use thereof. Also provided are methods for decreasing saturated fatty acid levels as a component of total triglycerides found in plant oils. The method generally comprises growing a soybean plant having integrated into its genome a DNA construct comprising, in the 5′ to 3′ direction of transcription, a promoter functional in a soybean plant seed cell, a DNA sequence encoding a KAS protein, and a transcription termination region functional in a plant cell. The present invention also provides a soybean seed with less than about 3.5 weight percent total saturated fatty acids.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: March 16, 2004
    Assignee: Calgene LLC
    Inventor: Katayoon Dehesh
  • Patent number: 6689880
    Abstract: The present invention provides a DNA construct composition that relates to transgenic glyphosate tolerant wheat plants. The invention relates to the wheat plant 33391, the progeny thereof and to methods for the detection of wheat plant 33391 and its progeny and compositions thereof.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: February 10, 2004
    Assignee: Monsanto Technology LLC
    Inventors: Guilan Chen, Catherine M. Hironaka, Hua-ping Zhou
  • Patent number: 6663906
    Abstract: Fructose-1,6-bisphosphate aldolase (FDA) is an enzyme reversibly catalyzing the reaction converting triosephosphate into fructose-1,6-bisphosphate. In the leaf, this enzyme is located in the chloroplast (starch synthesis) and the cytosol (sucrose biosynthesis). Transgenic plants were generated that express the E. coli fda gene in the chloroplast to improve plant yield by increasing leaf starch biosynthetic ability in particular and sucrose production in general. Leaves from plants expressing the fda transgene showed a significantly higher starch accumulation, as compared to control plants expressing the null vector, particularly early in the photoperiod, but had lower leaf sucrose. Transgenic plants also had a significantly higher root mass. Furthermore, transgenic potatoes expressing fda exhibited improved uniformity of solids.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: December 16, 2003
    Assignee: Monsanto Technology LLC
    Inventors: Gerard F. Barry, Nordine Cheikh, Ganesh M. Kishore
  • Patent number: 6600088
    Abstract: Improved methods for the identification of transgenic plants containing NPTII protein are disclosed. Application of organosilicone surfactant in combination with kanamycin and/or paromomycin facilitates the identification of plants containing NPTII protein.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: July 29, 2003
    Assignee: Monsanto Company
    Inventors: Arlene R. Howe, Paul C. C. Feng
  • Patent number: 6596538
    Abstract: By this invention, nucleic acid sequences encoding for fatty acyl-CoA: fatty alcohol acyltransferase (wax synthase) are provided, wherein said wax synthase is active in the formation of a wax ester from fatty alcohol and fatty acyl-CoA substrates. Of special interest is are nucleic acid sequences obtainable from a jojoba embryo wax synthase having an apparent molecular mass of approximately 33 kD. Also considered are amino acid and nucleic acid sequences obtainable from wax synthase proteins and the use of such sequences to provide transgenic host cells capable of producing wax esters.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: July 22, 2003
    Assignee: Calgene LLC
    Inventors: Kathryn Dennis Lardizabal, James George Metz, Michael W. Lassner
  • Patent number: 6521603
    Abstract: A method of controlling Take-all disease of plants, by applying, preferably to the seeds prior to planting, a fungicide of the formula wherein Z1, and Z2 are C and are part of an aromatic ring which is benzene.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: February 18, 2003
    Assignee: Monsanto Technology LLC
    Inventors: Dennis Paul Phillion, Diane Susan Braccolino, Matthew James Graneto, Wendell Gary Phillips, Karey Alan Van Sant, Daniel Mark Walker, Sai Chi Wong
  • Patent number: 6441277
    Abstract: Fructose-1,6-bisphosphate aldolase (FDA) is an enzyme reversibly catalyzing the reaction converting triosephosphate into fructose-1,6-bisphosphate. In the leaf, this enzyme is located in the chloroplast (starch synthesis) and the cytosol (sucrose biosynthesis). Transgenic plants were generated that express the E. coli fda gene in the chloroplast to improve plant yield by increasing leaf starch biosynthetic ability in particular and sucrose production in general. Leaves from plants expressing the fda transgene showed a significantly higher starch accumulation, as compared to control plants expressing the null vector, particularly early in the photoperiod, but had lower leaf sucrose. Transgenic plants also had a significantly higher root mass. Furthermore, transgenic potatoes expressing fda exhibited improved uniformity of solids.
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: August 27, 2002
    Assignee: Monsanto Technology LLC
    Inventors: Gerard F. Barry, Nordine Cheikh, Ganesh M. Kishore
  • Patent number: 6410558
    Abstract: A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula wherein Z1 and Z2 are C or N and are part of an aromatic ring selected from benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole, and isothiazole; A is selected from —C(X)-amine, —C(O)—SR3, —NH—C(X)R4, and —C(═NR3)—XR7; B is —Wm—Q(R2)3 or selected from o-tolyl, 1-naphthyl, 2-naphthyl, and 9-phenanthryl, each optionally substituted with halogen or R4; Q is C, Si, Ge, or Sn; W is —C(R3)pH(2−p)—; or when Q is C, W is selected from —C(R3)pH(2−p)—, —N(R3)mH(1−m)—, —S(O)p—, and —O—; X is O or S; n is 0, 1, 2, or 3; m is 0 or 1; p is 0, 1, or 2; each R is independently selected from a) halo, formyl, cyano, amino, nitro, thiocyanato, isothiocyanato, trimethylsilyl, and hydroxy; b) C1-C4 alkyl, alkenyl, alkynyl,
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: June 25, 2002
    Assignee: Monsanto Technology LLC
    Inventors: Dennis Paul Phillion, Diane Susan Braccolino, Matthew James Graneto, Wendell Gary Phillips, Karey Alan Van Sant, Daniel Mark Walker, Sai Chi Wong
  • Patent number: 6359156
    Abstract: The invention relates to compounds having usefulness in the control of Take-All disease in plants, particularly cereals, a method for the control of Take-All disease, and fungicidal compositions for carrying out the method. Compounds of the invention are oximes or hydrazones of arylgloxamides or heteroarylglyoxamides or cycloalkenylglyoxamides.
    Type: Grant
    Filed: August 21, 2001
    Date of Patent: March 19, 2002
    Assignee: Monsanto Technology LLC
    Inventor: Dennis P. Phillion
  • Patent number: 6297271
    Abstract: The invention relates to compounds having usefulness in the control of Take-All disease in plants, particularly cereals, a method for the control of Take-All disease, and fungicidal compositions for carrying out the method. Compounds of the invention are oximes or hydrazones of arylgloxamides or heteroarylglyoxamides or cycloalkenylglyoxamides.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: October 2, 2001
    Assignee: Monsanto Technology LLC
    Inventor: Dennis P. Phillion
  • Patent number: 6291513
    Abstract: The fungicidal compound 4,5-dimethyl-N-2-propenyl-2-(trimethylsilyl)-3-thiophenecarboxamide (Formula (I)) has shown superior and unexpected control of the growth of the soil-borne fungus Gaeumannomyces graminis (Gg). The present invention provides a novel compound for synthesizing the compound of Formula (I) which uses the compound 4-hydroxy-4,5-dimethyl-2-trimethylsilanyl-dihydrothiophene-3-carboxylic acid allylamide (Formula (II)) as well as novel compounds of synthesizing the allylamide. In addition, Formula (II) itself has unexpectedly been found to provide control of Gg.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: September 18, 2001
    Assignee: Monsanto company
    Inventors: Wendell G. Phillips, Michael K. Mao, Chun Ma, Thomas L. Fevig
  • Patent number: 6225114
    Abstract: DNA encoding glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate (EPSP) synthases, plant genes encoding the glyphosate-tolerant enzymes, and plant transformation vectors containing the genes are disclosed. The DNA encodes glyphosate-tolerant EPSP synthases modified by substitution of an alanine residue for a glycine residue in a first conserved sequence found between positions 80 and 120, and a threonine residue for an alanine residue in a second conserved sequence found between positions 170 and 210 in the mature wild type EPSP synthase.
    Type: Grant
    Filed: February 1, 1999
    Date of Patent: May 1, 2001
    Assignee: Monsanto Company
    Inventors: David Alan Eichholtz, Charles Scott Gasser, Ganesh Murthy Kishore