Patents Represented by Attorney Timothy H. Bencen & Van Dyke, P.A. Van Dyke, Esq.

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  • Adenovirus vectors for gene therapy
    Patent number: 6140087
    Abstract: The invention comprises a series of adenovirus-based vectors having deletions in the E1 and/or E3 regions, and also insertions of pBR322 sequences, which can be used to deliver nucleic acid inserts into host cells, tissues or organisms that then can express the insert. The invention includes the use of the vectors in introducing genes into cells, in making vaccines and in gene therapy.
    Type: Grant
    Filed: May 31, 1994
    Date of Patent: October 31, 2000
    Assignee: AdVec, Inc.
    Inventors: Frank L. Graham, Andrew Bett, Ludvik Prevec, Wael M. Haddara