Abstract: The invention includes a cell-growth-on-bead assay for screening a one-bead-one-compound combinatorial bead library to identify synthetic ligands for cell attachment and growth or proliferation of epithelial and non-epithelial cells. Cells are incubated with a compound bead library for 24 to 72-hours, allowing them to attach and grow on the beads. Those beads with cells growing are removed, and the ligand on the bead is identified. Also provided are ligands specific for cancer cells.
Abstract: An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into container adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the container to control the operation of valves directing the collection of each component. Each component may then be separated into its own storage container.
Type:
Grant
Filed:
April 8, 2002
Date of Patent:
July 10, 2007
Assignee:
ThermoGenesis Corporation
Inventors:
Philip H. Coelho, Eric Sommer, Richard Klosinski, Jim Hobbs
Abstract: A loading station having a dispensing manifold for loading syringe pairs with thrombin and adhesive and clotting proteins for use as a biological adhesive. The resulting loaded syringe pairs are compatible with a variety of biological adhesive dispensers and may be used in a surgical setting.
Type:
Grant
Filed:
December 15, 2003
Date of Patent:
February 27, 2007
Assignee:
ThermoGenesis Corp.
Inventors:
Eric Sommer, Philip Henry Coelho, Phil Kingsley
Abstract: In a method and apparatus for severing roots of bean sprouts, a severing table has a plurality of ridges formed at predetermined intervals and extending in parallel with a direction in which a cutter blade is moved. Each ridge is formed with a number of severing slits each of which has such a width that a root of a bean sprout falls into each severing slit. The bean sprouts are continuously supplied onto the severing table while a cutter blade is moved along an upper face of the severing table and water is being sprinkled over the severing table so that roots of the bean sprouts on the severing table flow into the severing slits. The roots of the bean sprouts fallen in the severing slits are severed by the cutter blade. The bean sprouts from which the roots have been severed are conveyed out of the severing table with movement of the cutter blade.