Abstract: The invention teaches a hinged clip (10) comprising two arms (22), each arm having a free end (34) and an extension forming the other end, resilient bias means urging the free ends together, the extensions being movable towards one another against the force of the resilient bias means to separate the said free ends characterised in that the resilient bias means is non-removably secured to each arm. An edge protector for an article (14) having sides (16) joined by an edge (12) is also taught, as is the method of manufacture and use.
Abstract: A filtration cassette of a type comprising filter sheets arranged in a multilaminate, peripherally bonded array, wherein the filter sheets alternate with permeate and retentate sheets. A stacked assembly of such filtration cassettes may be employed to form a stacked cassette filter. The filtration cassettes and filter of the invention may be advantageously employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.
Abstract: An artificial insemination apparatus for insertion into a cervix of a sow, including a tubular passage member which is helically coiled at a distal end. The helically coiled distal end terminates in an open tip including an opening communicating with a bore of the tubing. The helically coiled distal end is inserted into and is secured by the muscular folds in the cervix, and semen is transmitted therethrough.
Abstract: Fungi and fungal spores which are modified to confer a transmissible hypovirulent phenotype, related polynucleotides, and use of these fungi to control fungal diseases.
Type:
Grant
Filed:
June 2, 1995
Date of Patent:
February 2, 1999
Assignee:
University of Maryland Biotechnology Institute
Abstract: The invention relates to a method of combating an animal parasite in a host which comprises delivering an anti-parasitic protein to the parasite or to a locus thereof by administering the protein to the host animal as a medicament or as a food. The anti-parasitic protein may be an inhibitor of an enzyme of the parasite, for example an inhibitor of a digestive enzyme such as a cysteine protease inhibitor. The parasite may be a helminth or a protozoan, for example, a nematode. According to one embodiment the anti-parasitic protein is expressed in a transgenic plant which may be a dietary crop for the host animal.
Type:
Grant
Filed:
December 20, 1996
Date of Patent:
January 26, 1999
Assignee:
The University of Leeds
Inventors:
Howard John Atkinson, Vas Michael Koritsas, Donald Lewis Lee, Andrew Neilson MacGregor, Judith Elizabeth Smith
Abstract: A method for the treatment or prophylaxis of one or more conditions or disorders selected from the group consisting of physiological pain, diarrhea, urinary incontinence, mental illness, drug and alcohol addiction/overdose, lung edema, depressioysema, apnea, cognitive disorders and gastrointestinal disorders, comprising administration to a subject in need of such treatment or prophylaxis, of a diarylmethylpiperazine or piperidine opioid compound.
Type:
Grant
Filed:
May 28, 1997
Date of Patent:
December 29, 1998
Assignee:
Delta Pharmaceuticals, Inc.
Inventors:
Kwen-Jen Chang, Grady Evan Boswell, Dulce Garrido Bubacz, Mark Allan Collins, Ann Otstot Davis, Robert Walton McNutt, Jr.
Abstract: The present invention relates to, inter alia, methods and compositions for reducing, treating or preventing respiratory depression in an animal, using a compound of the formula: ##STR1## wherein: Ar, G, Z, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are as defined in specification,or a pharmaceutically acceptable ester or salt thereof.
Type:
Grant
Filed:
June 5, 1996
Date of Patent:
September 15, 1998
Assignee:
Delta Pharmaceutical, Inc.
Inventors:
Kwen-Jen Chang, Robert W. McNutt, Jr., Hugh O. Pettit, Michael J. Bishop