Patents Represented by Attorney, Agent or Law Firm William A. Teoli, Jr.
  • Patent number: 6235684
    Abstract: A method of combating phytopathogenic diseases on crop plants which comprises applying to the crop plants or the locus thereof being infested with said phytopathogenic disease an effective amount of a combination of a) a 2-(5-phenyl-3,6-diaza-2,7-dioxa-octa-3,5-dienyl)phenylacrylamide of formula I wherein R1 is hydrogen, fluoro or chloro, R2 is methyl, ethyl, trifluoromethyl, trifluoromethoxy, cyano, fluoro, chloro or bromo, with the proviso that R2 cannot be fluoro, chloro or bromo, when R1 is hydrogen; in association with b) a broad variety of otherplant fungicides is particularly effective in combating or preventing fungal diseases of crop plants. These combinations exhibit synergistic fungicidal activity.
    Type: Grant
    Filed: February 28, 2000
    Date of Patent: May 22, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Gertrude Knauf-Beiter, René Zurflüh, Bettina Gsell
  • Patent number: 6228884
    Abstract: If the R-enantiomer of metalaxyl, furalaxyl or benalaxyl is used, this results in a markedly increased biodegradability of these plant fungicides in the soil and a higher activity on the plants, as compared with the data of the racemic active ingredients. Fungicidal compositions exhibiting said improved properties comprise either of these fungicides with a content of R-enantiomer of more than 70 percent by weight based on the total amount of active ingredient.
    Type: Grant
    Filed: October 19, 1998
    Date of Patent: May 8, 2001
    Assignee: Syngenta Investment Corporation
    Inventors: Cosima Nuninger, John Edward Nicholas Goggin, Dino Sozzi, Holm Ellgehausen
  • Patent number: 6225319
    Abstract: An agrochemical composition, comprising at least two active ingredient components together with a suitable carrier, wherein component I is I) difenoconazole (=cis,trans-3chloro-4-[4-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl]phenyl 4-chlorophenyl ether) and wherein component II is IIA) fluquinconazole (=3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin) or IIB) 4,5-dimethyl-N-2-propenyl-2-(trimethylsilyl)-3-thiophencarboxamid which is especially suitable in the control and prevention of disease infestation on seed.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: May 1, 2001
    Assignee: Syngenta Crop Protection, Inc.
    Inventor: Birgit Forster
  • Patent number: 6222037
    Abstract: A process for the preparation of a compound of formula I wherein R1 is selected from the group consisting of —CO2CH3, —CON(CH3)2, —OCH2CF3, —N(CH3)COCH3, —N(CH3)SO2CH3, —CF3, and —SO2C2H5; R2 is selected from the group consisting of hydrogen and —CF3; and M is selected from the group consisting of sodium and potassium; comprising: reacting a compound of formula IV in an aprotic, organic solvent with a compound of formula V wherein R1, R2, and M are as defined above.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: April 24, 2001
    Assignee: Syngenta Crop Protection, Inc.
    Inventor: Andrea Rolf Sting
  • Patent number: 6218559
    Abstract: Reaction products of an iridium(III) salt or a hydrate thereof, a diphosphine having secondary phosphine groups and a metal or ammonium chloride, bromide or iodide are excellent hydrogenation catalysts for ketimine. Using chiral diphosphines and prochiral ketimines, diastereoisomeric secondary amines are obtained in high optical yields.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: April 17, 2001
    Assignee: Novaritis Corporation
    Inventors: Felix Spindler, Ulrich Pittelkow
  • Patent number: 6211381
    Abstract: The invention relates to a process for preparing a compound of formula (I), in which X is CH or N, Y is NO2 or CN, Z is CHR3, O, NR3 or S, R1 and R2 are either each, independently of the other, hydrogen or unsubstituted or R4-substituted alkyl or together a two- or three-membered alkylene bridge or a two- or three-membered alkylene bridge in which one member is replaced by a hetero member selected from the group, consisting of NR5, O and S, R3 is H or unsubstituted or R4-substituted alkyl, R4 is an unsubstituted or substituted aryl or heteroaryl group, and R5 is H or alkyl, which comprises a) reacting a compound of formula (II) with a chlorinating agent or b1) initially reacting a compound of formula (IV) with a compound of formula (V) and b2) further reacting the compound of formula (II) obtainable thereby, with or without intermediate isolation, with a chlorinating agent, to intermediates used in this process, to the use of these intermediates and to a process for the preparation of these intermediates.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: April 3, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Henry Szczepanski, Thomas Göbel, Ottmar Franz Hüter, Anthony Cornelius O'Sullivan, Marcel Senn, Thomas Rapold, Peter Maienfisch, Thomas Pitterna
  • Patent number: 6207830
    Abstract: Aryl- or heteroaryluracils of formula I wherein R1 signifies methyl or ethyl; R2 signifies —CF3, —CClF2, —CCl2F, or —C2F5; and Q is an aryl or heteroaryl group; are produced whereby a compound of formula II O═C═N—Q  (II) is reacted at a temperature of −5° C. to +40° C. with an enamine of formula III wherein R19 signifies C1-C6-alkyl, in the presence of a solvent and of 0.1 to 0.4 equivalents of a base with respect to the employed enamine of formula III. The compounds of formula I are useful as herbicides. An example of the compounds of formula I is 2-chloro-5-(3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1-(2H)pyrimidinyl)-benzoic acid 1-aalyloxycarbonyl-1-methyl-ethyl-ester.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: March 27, 2001
    Assignee: Syngenta Crop Protection, Inc.
    Inventor: Andrea Rolf Sting
  • Patent number: 6204221
    Abstract: Compounds of formula (I) in which A is ═N— or (a); W is a group (W1), (W2) or (W3); R11 is hydrogen, fluorine, chlorine, bromine or methyl; and R1 to R5, R13,n1 and n13 are as defined in claim 1, and the pyrazole N-oxydes, agrochemically tolerated salts and stereoisomers of these compounds of formula (I), have good pre- and post-emergent selective herbicidal properties. The preparation of these compounds and their use as herbidical active substances are described.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: March 20, 2001
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Kurt Nebel, Hans-Georg Brunner, Rolf Schurter
  • Patent number: 6194463
    Abstract: &agr;-Amino acid amides of formula (I) wherein the substituents are defined as follows: n is a number zero or one; R1 to R7 are as defined herein; R8 is C1-C6alkyl, C3-C6alkenyl or C3-C6alkynyl; R9 is C3-C8cycloalkyl; a C1-C6alkyl, C3-C6alkenyl or C3-C6alkynyl group substituted by one or more halogen atoms; or a group (a) wherein p and q are identical or different and are each independently of the other a number zero or one; and R13, R14, R15 and R16 are identical or different and are each independently of the others hydrogen or C1-C4alkyl; X is hydrogen, in which case p and q must have the value zero; phenyl, unsubstituted or mono- or poly-substituted by halogen, nitro, cyano, carboxy, C2-C6alkenyl, C2-C6alkenyl, C1-C6haloalkyl, C3-C6alkenyloxy, C3-C6alkynyloxy, C3-C7cycloalkyl, C1-C6haloalkoxy, C1-C6alkylthio, C1-C6alkoxycarbonyl, C3-C6alkenyloxycarbonyl, C3-C6alkynyloxycarbonyl, C1-C6or by C1-C6alkoxy, cyano, —COOR17; —COR18 or a group (b) wherein R17 and R21 are each independently of the other
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: February 27, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventor: Martin Zeller
  • Patent number: 6194611
    Abstract: &agr;-Amino acid amides of formula (I) wherein the substituents are defined as follows: n is the number zero or one; R1 to R7 are as herein defined; R8 is C1-C6alkyl, C3-C6alkenyl or C3-C6alkynyl; R9 is C3-C8cycloalkyl; a C1-C6alkyl, C3-C6alkenyl or C3-C6alkynyl group substituted by one or more halogen atoms; or a group (a) wherein p and q are identical or different and are each independently of the other the number zero or one; and R13, R14, R15 and R16 are identical or different and are each independently of the others hydrogen or C1-C4alkyl; and X is hydrogen, in which case p and q must have the value zero; phenyl unsubstituted or mono- or poly-substituted by halogen, nitro, cyano, carboxy, C2-C6alkenyl, C2-C6alkynyl, C1-C6haloalkyl, C3-C6alkenyloxy, C3-C6alkynyloxy, C3-C7cycloalkyl, C1-C6haloalcoxy, C1-C6alkylthio, C1-C6alcoxycarbonyl, C3-C6alkenyloxycarbonyl, C3-C6alkynyloxycarbonyl, C1-C6alkyl or by C1-C6alkoxy; cyano; —COOR17; —COR18 or a group (b) wherein R17 and R21 are each independently
    Type: Grant
    Filed: April 16, 1998
    Date of Patent: February 27, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventor: Martin Zeller
  • Patent number: 6187800
    Abstract: A method for treating or preventing mastitis in mammals is disclosed. The method contemplates the intramammary injection or dipping the teat with micrococcin antibiotics, preferably micrococcin P1 or P2, which do not interfere with the production of cheese and yoghurt using milk from treated animals. Hydrophobic antibiotics such as micrococcin P1 or P2 can be administered prior to infection to effectively suppress the rate, severity, and duration of subsequent bacterial infection, or can be administered subsequent to infection to effectively treat mastitis.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: February 13, 2001
    Assignee: Novartis Animal Health U.S., Inc.
    Inventors: Bruno Suri, Catherine Georges, John Edmondson Peel
  • Patent number: 6187927
    Abstract: The invention relates to a process for preparing a compound of formula (I) in which A is chlorine or 3-methyl-4-nitroimino-perhydro-1,3,5-oxadiazin-5-yl; to intermediates used in this process; to the use of these intermediates; and to a process for the preparation of these intermediates. The compounds of formula (I) are valuable intermediates in the process of preparing pesticidal, especially insecticidal or acaricidal, formulations.
    Type: Grant
    Filed: March 6, 1998
    Date of Patent: February 13, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventor: Thomas Pitterna
  • Patent number: 6180563
    Abstract: A herbicidal composition comprising, in addition to conventional inert formulation adjuvants, the compound of formula I in admixture with a synergistically effective amount of at least one active ingredient from the substance classes of formula IV e.g., glyphosate or glufosinate.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: January 30, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Willy R{umlaut over (u)}egg, Manfred Hudetz
  • Patent number: 6175018
    Abstract: (R)(+)-2-[4-(5-chloro 3-fluoropyridin-2-yloxy)-phenoxy]-propionic acid propinyl ester is produced by converting a compound of formula II in an inert organic solvent, without isolation of the intermediate products, with M2CO3, in which M is sodium or potassium, into the compound of formula III reacting this with the compound of formula IV to form the compound of formula V and converting this with a compound of formula VI wherein Z signifies phenylsulphonyl, tosyl, methylsulphonyl, nosyl, bromophenyl, Cl-, Br- or CICO-, into the compound of formula I.
    Type: Grant
    Filed: March 16, 1999
    Date of Patent: January 16, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Gottfried Seifert, Andrea Rolf Sting, Bernhard Urwyler
  • Patent number: 6162762
    Abstract: A selective herbicidal composition for controlling grasses and weeds in crops of cultivated plants, comprising a) a herbicidally effective amount of a herbicide of formula I ##STR1## and b) to antagonise the herbicide, an antidotally effective amount of a safener selected from the group of the compounds of formula 1.01 (CGA 185,072), 2.01, 2.05, 3.03, 4.001, 5.006 (benoxacor), and 6.02 (fluxofenim).
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: December 19, 2000
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Derek Cornes, Jutta Glock
  • Patent number: 6159899
    Abstract: A herbicidal composition comprising a compound of formula A ##STR1## or an agrochemically acceptable salt thereof and at least one compound from the substance classes of formulae I-VII.
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: December 12, 2000
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Manfred Hudetz, Norbert Nelgen
  • Patent number: 6156923
    Abstract: The invention relates to a process for the preparation of compounds of the formula ##STR1## or, if appropriate, a tautomer thereof, in each case in the free form or in salt form, in whichA, X, Y, Z, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.7, R.sub.9 and n are as defined in claim 1 and the C.dbd.N double bond marked with E has the E configuration, which comprisesa1) reacting either a compound of the formula (II) mentioned above with a compound of the formula (III) mentioned above, in which X.sub.1 is a leaving group, ora2) a compound of the formula (IV) mentioned above, if appropriate in the presence of a base, with a compound of the formula (V) mentioned above, orb1) reacting a compound of the formula (VI) mentioned above with a compound of the formula R.sub.7 --A--X.sub.2 (VII), in which X.sub.
    Type: Grant
    Filed: December 6, 1996
    Date of Patent: December 5, 2000
    Assignee: Novartis Corporation
    Inventors: Saleem Farooq, Stephan Trah, Hugo Ziegler, Rene Zurfluh
  • Patent number: 6156704
    Abstract: The invention relates to the compounds of Formula XA ##STR1## wherein X and Y represent independently hydrogen, fluorine or chlorine, Z.sub.1 is fluorine or chlorine and M is hydrogen or a salt forming moiety and Z.sub.2 ' is chlorine or fluorine; and the corresponding herbicidal composition and methods of use. The compounds of the invention are useful as auxin transport inhibitors (i.e. useful as herbicides) and useful as potentiators or enhancers of herbicides.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 5, 2000
    Assignee: Novartix AG
    Inventors: Richard J. Anderson, Ian S. Cloudsdale, Robert J. Lamoreaux, Kristine J. Schaefer, Jost Harr
  • Patent number: 6150386
    Abstract: Compounds of formula (I) and their possible isomers and isomer mixtures, in which (Z) is a group (a), (b), (c) or (d) and in which the other substituents are as defined herein.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: November 21, 2000
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Stephan Trah, Rene Zurfluh
  • Patent number: 6136816
    Abstract: This invention relates to fungicidal active ingredient mixtures comprising at least two active ingredient components together with a suitable carrier material, wherein component I is cyprodinil [=2-anilino-4-cyclopropyl-6-methyl-pyrimidine] and wherein component II is A) myclobutanil [=2-p-chlorophenyl-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile]; or B) iprodione [=3-(3,5-dichlorophenyl)-N-isopropyl-2,4-dioxoimidazolidine-1-carboxamide] , and to methods of using such mixtures in crop protection, especially in the control and prevention of disease infestation.
    Type: Grant
    Filed: October 9, 1998
    Date of Patent: October 24, 2000
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Gertrude Knauf-Beiter, Hans Steiner