Abstract: Provided are methods for reducing the excipient load of pharmaceutical formulations containing 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide as the active pharmaceutical ingredient, and compositions related thereto. In particular, provided is a pharmaceutical product comprising 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide and a stabilizer admixed throughout a solid-form unilamellar matrix, wherein the ratio of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide to stabilizer ranges from about 2:3 to about 1:10, and related methods of forming the pharmaceutical product.

Abstract: Methods and apparatus for forming a housing, such as for an electronic device, from multi-layer materials are disclosed. The multi-layer materials include at least two layers. Typically, one or more of the layers are metal. However, different layers of the multi-layer materials can be different metals. In one embodiment, an inner layer of the multi-layer materials can be provided with or form internal features that can be for attaching parts or components to the multi-layer materials. In another embodiment, processing of an inner layer of the multi-layer materials can facilitate part formation with increased curvature and/or internal part clearance. In another embodiment, the multi-layer materials can include an intermediate layer that facilitates creation of internal features that can be for attaching parts or components to the multi-layer materials.

Abstract: A cutting tool includes one or more cutting portions, each including an insert pocket having a cutting insert releasably retained therein. The cutting insert has a bottom surface, including a plurality of surfaces, engaging a plurality of walls of the insert pocket in a plurality of sloping and non-sloping engagement regions. These engagement means provide secure and stable clamping of the cutting insert, and prevent displacement of the cutting insert during intensive cutting operations, such as high speed milling, e.g., by significantly decreasing the force exerted on the screw that fastens the cutting insert in the insert pocket.

Abstract: A liquid atomizer for agricultural use includes at least one canal in fluid communication via a chamber with an outlet. At least a section of the canal extends along a straight line and tangentially opens into the chamber.

Abstract: A method, system, and apparatus for monitoring electrical safety conditions and managing energy consumption using a microcontroller embedded in a circuit breaker. The microcontroller receives a plurality of inputs detected by a plurality of sensors in the circuit breaker. An amount of energy consumed during a preset interval of time is determined. A temperature of a circuit breaker panel board detected by a temperature sensor is received and compared with a preset temperature alarm threshold value to determine a panel board overheating condition. A condition of the neutral conductor is determined based on a plurality of line voltages and currents received from a plurality of voltage and current sensors by comparing a voltage differential with a preset threshold differential voltage value.

Abstract: An apparatus and method for manufacturing a rod member for a cigarette filter element is provided. Each rod member defines a longitudinal axis and includes a generally longitudinally-extending filter material. A rod-forming unit is configured to form a continuous supply of a filter material into a continuous cylindrical rod member. An object insertion unit is configured to introduce a plurality of objects into engagement with the rod member along the longitudinal axis. A dispensing device is configured to selectively dispense a liquid substance into the filter material, substantially commensurately with the introduction of the plurality of objects into engagement with the rod member, wherein the liquid substance is configured to affect an attribute associated with the objects. A rod-dividing unit is configured to divide the rod member into a plurality of rod portions such that each rod portion includes at least one object and a portion of the liquid substance.

Abstract: The present invention relates to the use of an antisecretory protein or a derivative, homologue, and/or fragment thereof, having antisecretory activity, and/or a pharmaceutically active salt thereof, for the manufacture of a pharmaceutical composition and/or a medical food for the treatment and/or prevention of compartment syndrome. A compartment syndrome may be caused by or a cause of a variety of other conditions which are also encompassed by the present invention, such as viral and bacterial infections. Furthermore, the invention relates to a method for the treatment and/or prevention of compartment syndrome in a mammal in need thereof.

Abstract: A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relics on the combination of three functional elements: the AC electric field-induced assembly of planar aggregates; the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The present invention provides a set of fundamental operations enabling interactive control over the creation and placement of planar arrays of several types of particles and biomolecules and manipulation of array shape and size. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations.

Abstract: Various containers with an enlarged base for receiving a food item are provided. The containers may be formed from various sleeves for heating, browning, and crisping a food item. Blanks for forming such sleeves and containers also are provided. The blanks, sleeves, and/or containers may include a removable portion at least partially defined by a line of disruption.

Abstract: An air cargo loading system also includes a controller, a main control panel and a plurality of PDUs (PDUs), at least the controller and the PDUs being connected by a wired network. Each PDU has a motor, at least one driver roller element coupled to said motor, a light source, a light detector, and a processor. The light detector of each PDU is configured to receive and process an incoming coded light signal from a wireless remote control handset. The PDU's processor determines whether the received coded light signal is a valid command signal and, if so, provides a command information signal to the controller via the wired network. The controller decodes the command information signal and, in view of its knowledge of container locations, various switch settings and other status information, the controller then sends the appropriate control signals to turn on the required PDUs in response thereto.

Abstract: An access pad is used to provide access to a functional block of an integrated circuit (IC) device. The access pad is formed using dummy metal in an open space in a metallization level that is between a top metallization level and a base level on which the functional block is formed in the IC device. The access pad at the metallization level provides a contact to access an underlying circuit of the functional block so that the functional integrity of the functional block of the IC device can be verified during probing.

Abstract: A cutting insert is removably mountable on an insert seat formed in a peripheral of a tool body rotated around an axis O and of substantial disc shape. The cutting insert includes a substantially planar insert body of a substantially square shape in plan view, a flank at an upper face of the body, a rake face at a side of the body intersecting with the flank, and a cutting edge at an intersection ridge between the rake face and the flank. The cutting edge is a substantial involute in side view of the body, the rake face is inclined to an inside of the body from an upper toward a lower face, and at least a front end arranged in a peripheral of the tool body is concave constituting a part of a substantially conical side face.

Abstract: A tool holder for holding a shank of a cutting member. The tool holder has a socket for receiving the shank and a set screw rotatable in a set screw hole to advance along a first direction; and at least one clamping member that applies a force to the shank along a second direction responsive to advance of the set screw in the first direction to clamp the shank in the socket.

Abstract: By being embedded in a portable computing device, a battery pack is made essentially inaccessible to unauthorized users, thereby allowing for a battery pack that can be made smaller and of lighter construction material, thereby facilitating greater component density within the portable computing device, lower cost to manufacture, and more environmentally secure.