Patents Represented by Law Firm Wyatt, Gerber Shoup and Badie
  • Patent number: 4824436
    Abstract: Process for local administration of heparin or other agents to inhibit arterial smooth muscle cell proliferation utilizing a catheter.
    Type: Grant
    Filed: April 21, 1987
    Date of Patent: April 25, 1989
    Inventor: Harvey Wolinsky
  • Patent number: 4784948
    Abstract: Methods and compositions are provided for the cloning and expression of Streptococcus pyogenes M protein genes, and, in particular, types 5, 6 and 24 genes in single-cell host organisms. The streptococcal M protein produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against S. pyogenes infections. The gene for the M protein may further be employed as a molecular probe for the accurate identification of streptococci in infected body tissues and fluids.
    Type: Grant
    Filed: June 18, 1984
    Date of Patent: November 15, 1988
    Assignees: The Rockefeller University, Emory University
    Inventors: June R. Scott, Vincent A. Fischetti
  • Patent number: 4783470
    Abstract: Anticoagulant is derived from hematin on standing in a slightly alkaline medium and may be isolated therefrom.
    Type: Grant
    Filed: January 14, 1986
    Date of Patent: November 8, 1988
    Assignee: The Rockefeller University
    Inventor: Robert L. Jones
  • Patent number: 4771099
    Abstract: The silicone rubber composition of the invention comprises, as the peroxide curing agent, a neopentane diol derivative represented by the general formulaR.sup.1 --O--O--CO--O--CH.sub.2 --C(CH.sub.3).sub.2 --CH.sub.2 --O--CO--O--O--R.sup.2,in which R.sup.1 and R.sup.2 are each, independently from the other, a monovalent hydrocarbon group having 3 to 10 carbon atoms or a silyl group of the general formula --SiR.sup.3.sub.3, R.sup.3 being a methyl, ethyl or phenyl group, such as trimethyl silyl, in admixture with a diorganopolysiloxane and a reinforcing silica filler. By virtue of this unique formulation, the silicone rubber composition is suitable for hot-air vulcanization without compression as in the vulcanization process by extrusion molding followed by heating in a hot-air oven.
    Type: Grant
    Filed: November 16, 1987
    Date of Patent: September 13, 1988
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Kunio Itoh, Takeo Yoshida, Masaharu Takahashi
  • Patent number: 4764396
    Abstract: A method for preventing aluminum corrosion in electronic parts which comprises adding lead hydroxy apatite and/or cadmium hydroxy apatite to constituents of the electronic parts through which halogen ions pass, so that said ions may be captured by said apatites in said constituents.
    Type: Grant
    Filed: September 24, 1987
    Date of Patent: August 16, 1988
    Assignee: Toagosei Chemical Industry Co., Ltd.
    Inventors: Hideki Kato, Noriyuki Yamamoto
  • Patent number: 4760092
    Abstract: Method of treating demyelinating diseases such as multiple sclerosis by treatment with colchicine or colchiceine.
    Type: Grant
    Filed: December 3, 1986
    Date of Patent: July 26, 1988
    Assignee: The Rockefeller University
    Inventor: Herman J. Weinreb
  • Patent number: 4758808
    Abstract: An impedance element having a longitudinal current path surrounded by ferromagnetic material is implemented by the combination of a single rectangular ferrite chip, some through holes provided through said chip, through hole conductors plated on surface of said through holes, a pair of terminal conductors plated at ends of said chip, a surface conductive pattern deposited on front and back surfaces of said ferrite chip so that said through hole conductors are connected in series to one another between said terminal conductors, and insulation layers covering said surface conductors and said through hole conductors on both front and back surfaces of said ferrite chip. The present impedance element is small in size with relatively large impedance, and is applicable for instance to a high frequency noise filter.
    Type: Grant
    Filed: June 29, 1987
    Date of Patent: July 19, 1988
    Assignee: TDK Corporation
    Inventors: Yoshinori Sasaki, Toshio Watanabe, Isao Yokoyama
  • Patent number: 4756952
    Abstract: The inventive water-swellable caulking material for water-leakage prevention is of the type formed of a composition comprising a rubbery polymer and a highly water-absorptive resin and useful in the caulking works of a construction joint of concrete. Different from the conventional caulking materials of the type, the inventive caulking material is provided on the surface of a shaped body of the water-swellable composition with a coating film which is impervious to neutral water but exhibits water-permeability when contacted with an alkaline water of an alkalinity such as in an uncured concrete mixture so that the caulking material is prevented from premature or untimely expansion by swelling even when inadvertently contacted with water prior to application to the working site but capable of promptly expanding when contacted with an uncured concrete mixture with alkalinity.
    Type: Grant
    Filed: April 8, 1985
    Date of Patent: July 12, 1988
    Assignee: C.I. Kasei Co., Ltd.
    Inventors: Hiroharu Sasayama, Yuji Ishihara
  • Patent number: 4757121
    Abstract: The inventive composition is a silicone-based softening agent for synthetic fibers such as waddings of polyester fibers without the disadvantage of yellowing caused by heat or in the lapse of time. The essential ingredients of the inventive composition are a combination of two different amino-substituted organopolysiloxanes, an opoxy-containing alkoxysilane compound such as 3-glycidyloxypropyl methyl dimethoxy silane and a monoepoxy compound such as glycidyl alcohol each in a specified amount. Characteristically, one of the amino-substituted organopolysiloxane components is a reaction product of an amino-substituted organopolysiloxane and an organic opoxy compound.
    Type: Grant
    Filed: September 15, 1987
    Date of Patent: July 12, 1988
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Masaki Tanaka, Hiroshi Ohashi
  • Patent number: 4757134
    Abstract: Describes IgA binding protein isolatable from Group B streptococci, methods of isolation and use in immunological testing procedures.
    Type: Grant
    Filed: February 13, 1986
    Date of Patent: July 12, 1988
    Assignee: The Rockefeller University
    Inventors: Milan Blake, Emil Gotschlich, Gregory J. Russell-Jones
  • Patent number: 4749700
    Abstract: Invention relates to nasal administration of physiologically active therapeutic agents and dosage forms useful for such administration.
    Type: Grant
    Filed: April 24, 1987
    Date of Patent: June 7, 1988
    Assignee: Nastech Pharmaceutical Co, Inc.
    Inventor: Jeffrey Wenig
  • Patent number: 4743538
    Abstract: Monoclonal antibodies which react specifically with a complementary rheumatic fever associated antigen on human B-lymphocytes derived from hybridoma cell line HB8783, process for preparing such antibodies, the use of antibodies for detecting rheumatic fever in mammals and test kit containing the antibodies.
    Type: Grant
    Filed: April 17, 1985
    Date of Patent: May 10, 1988
    Assignee: The Rockefeller University
    Inventors: John B. Zabriskie, Daniel R. Buskirk
  • Patent number: 4743667
    Abstract: The invention relates to novel multifunctional organosiloxane monomers which can be represented by the general formulas: ##STR1## wherein, at least one of "X.sup.1 "-"X.sup.7 " is a group of the following structure: ##STR2## and its copolymerization with monofunctional organosiloxane monomers which can be represented by the general formulas: ##STR3## and alkyl and/or cyclic alkyl esters of acrylic, methacrylic acids and/or itaconate esters, and in some cases fluoroalkyl esters of acrylic, methacrylic acids and/or fluoroalkyl itaconate esters to produce excellent oxygen permeable hard contact lens material.Preferably, the copolymer includes cross-linking agents and wetting agents.Contact lenses manufactured from the materials can be easily machined and polished into hard contact lenses having solvent-resistance and sufficient permeabilities.
    Type: Grant
    Filed: July 22, 1986
    Date of Patent: May 10, 1988
    Assignee: Nippon Contact Lens, Inc.
    Inventors: Yutaka Mizutani, Tatsuo Harata, Naokatsu Tanahashi