Patents Represented by Law Firm Wyatt, Gerber Shoup and Badie
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Patent number: 4824436Abstract: Process for local administration of heparin or other agents to inhibit arterial smooth muscle cell proliferation utilizing a catheter.Type: GrantFiled: April 21, 1987Date of Patent: April 25, 1989Inventor: Harvey Wolinsky
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Patent number: 4784948Abstract: Methods and compositions are provided for the cloning and expression of Streptococcus pyogenes M protein genes, and, in particular, types 5, 6 and 24 genes in single-cell host organisms. The streptococcal M protein produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against S. pyogenes infections. The gene for the M protein may further be employed as a molecular probe for the accurate identification of streptococci in infected body tissues and fluids.Type: GrantFiled: June 18, 1984Date of Patent: November 15, 1988Assignees: The Rockefeller University, Emory UniversityInventors: June R. Scott, Vincent A. Fischetti
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Patent number: 4783470Abstract: Anticoagulant is derived from hematin on standing in a slightly alkaline medium and may be isolated therefrom.Type: GrantFiled: January 14, 1986Date of Patent: November 8, 1988Assignee: The Rockefeller UniversityInventor: Robert L. Jones
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Patent number: 4771099Abstract: The silicone rubber composition of the invention comprises, as the peroxide curing agent, a neopentane diol derivative represented by the general formulaR.sup.1 --O--O--CO--O--CH.sub.2 --C(CH.sub.3).sub.2 --CH.sub.2 --O--CO--O--O--R.sup.2,in which R.sup.1 and R.sup.2 are each, independently from the other, a monovalent hydrocarbon group having 3 to 10 carbon atoms or a silyl group of the general formula --SiR.sup.3.sub.3, R.sup.3 being a methyl, ethyl or phenyl group, such as trimethyl silyl, in admixture with a diorganopolysiloxane and a reinforcing silica filler. By virtue of this unique formulation, the silicone rubber composition is suitable for hot-air vulcanization without compression as in the vulcanization process by extrusion molding followed by heating in a hot-air oven.Type: GrantFiled: November 16, 1987Date of Patent: September 13, 1988Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Kunio Itoh, Takeo Yoshida, Masaharu Takahashi
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Patent number: 4764396Abstract: A method for preventing aluminum corrosion in electronic parts which comprises adding lead hydroxy apatite and/or cadmium hydroxy apatite to constituents of the electronic parts through which halogen ions pass, so that said ions may be captured by said apatites in said constituents.Type: GrantFiled: September 24, 1987Date of Patent: August 16, 1988Assignee: Toagosei Chemical Industry Co., Ltd.Inventors: Hideki Kato, Noriyuki Yamamoto
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Patent number: 4760092Abstract: Method of treating demyelinating diseases such as multiple sclerosis by treatment with colchicine or colchiceine.Type: GrantFiled: December 3, 1986Date of Patent: July 26, 1988Assignee: The Rockefeller UniversityInventor: Herman J. Weinreb
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Patent number: 4758808Abstract: An impedance element having a longitudinal current path surrounded by ferromagnetic material is implemented by the combination of a single rectangular ferrite chip, some through holes provided through said chip, through hole conductors plated on surface of said through holes, a pair of terminal conductors plated at ends of said chip, a surface conductive pattern deposited on front and back surfaces of said ferrite chip so that said through hole conductors are connected in series to one another between said terminal conductors, and insulation layers covering said surface conductors and said through hole conductors on both front and back surfaces of said ferrite chip. The present impedance element is small in size with relatively large impedance, and is applicable for instance to a high frequency noise filter.Type: GrantFiled: June 29, 1987Date of Patent: July 19, 1988Assignee: TDK CorporationInventors: Yoshinori Sasaki, Toshio Watanabe, Isao Yokoyama
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Patent number: 4756952Abstract: The inventive water-swellable caulking material for water-leakage prevention is of the type formed of a composition comprising a rubbery polymer and a highly water-absorptive resin and useful in the caulking works of a construction joint of concrete. Different from the conventional caulking materials of the type, the inventive caulking material is provided on the surface of a shaped body of the water-swellable composition with a coating film which is impervious to neutral water but exhibits water-permeability when contacted with an alkaline water of an alkalinity such as in an uncured concrete mixture so that the caulking material is prevented from premature or untimely expansion by swelling even when inadvertently contacted with water prior to application to the working site but capable of promptly expanding when contacted with an uncured concrete mixture with alkalinity.Type: GrantFiled: April 8, 1985Date of Patent: July 12, 1988Assignee: C.I. Kasei Co., Ltd.Inventors: Hiroharu Sasayama, Yuji Ishihara
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Patent number: 4757121Abstract: The inventive composition is a silicone-based softening agent for synthetic fibers such as waddings of polyester fibers without the disadvantage of yellowing caused by heat or in the lapse of time. The essential ingredients of the inventive composition are a combination of two different amino-substituted organopolysiloxanes, an opoxy-containing alkoxysilane compound such as 3-glycidyloxypropyl methyl dimethoxy silane and a monoepoxy compound such as glycidyl alcohol each in a specified amount. Characteristically, one of the amino-substituted organopolysiloxane components is a reaction product of an amino-substituted organopolysiloxane and an organic opoxy compound.Type: GrantFiled: September 15, 1987Date of Patent: July 12, 1988Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Masaki Tanaka, Hiroshi Ohashi
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Patent number: 4757134Abstract: Describes IgA binding protein isolatable from Group B streptococci, methods of isolation and use in immunological testing procedures.Type: GrantFiled: February 13, 1986Date of Patent: July 12, 1988Assignee: The Rockefeller UniversityInventors: Milan Blake, Emil Gotschlich, Gregory J. Russell-Jones
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Patent number: 4749700Abstract: Invention relates to nasal administration of physiologically active therapeutic agents and dosage forms useful for such administration.Type: GrantFiled: April 24, 1987Date of Patent: June 7, 1988Assignee: Nastech Pharmaceutical Co, Inc.Inventor: Jeffrey Wenig
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Patent number: 4743538Abstract: Monoclonal antibodies which react specifically with a complementary rheumatic fever associated antigen on human B-lymphocytes derived from hybridoma cell line HB8783, process for preparing such antibodies, the use of antibodies for detecting rheumatic fever in mammals and test kit containing the antibodies.Type: GrantFiled: April 17, 1985Date of Patent: May 10, 1988Assignee: The Rockefeller UniversityInventors: John B. Zabriskie, Daniel R. Buskirk
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Patent number: 4743667Abstract: The invention relates to novel multifunctional organosiloxane monomers which can be represented by the general formulas: ##STR1## wherein, at least one of "X.sup.1 "-"X.sup.7 " is a group of the following structure: ##STR2## and its copolymerization with monofunctional organosiloxane monomers which can be represented by the general formulas: ##STR3## and alkyl and/or cyclic alkyl esters of acrylic, methacrylic acids and/or itaconate esters, and in some cases fluoroalkyl esters of acrylic, methacrylic acids and/or fluoroalkyl itaconate esters to produce excellent oxygen permeable hard contact lens material.Preferably, the copolymer includes cross-linking agents and wetting agents.Contact lenses manufactured from the materials can be easily machined and polished into hard contact lenses having solvent-resistance and sufficient permeabilities.Type: GrantFiled: July 22, 1986Date of Patent: May 10, 1988Assignee: Nippon Contact Lens, Inc.Inventors: Yutaka Mizutani, Tatsuo Harata, Naokatsu Tanahashi