Abstract: The invention concerns a cosmetic or pharmaceutical composition. This composition is characterised in that it contains a microbial culture compatible in cosmetics or in pharmacy or in therapy, in particular a culture of micro-organisms selected among the acetic or lactic bacteria, freeze-dried yeast, suspensions of micro-organisms, fermented organic substances, for example fermented pollen, or an inactivated culture of bacteria of the genus bifidobacterium or of bacteria related to this genus mixed with an essential oil and an acid preferably an organic acid, such as citric acid. This composition has an activity for regenerating the skin, in particular anti-wrinkle properties, for erasing old scars, for repairing burnt tissues, for promoting skin healing, for eliminating pigmentary spots and also for promoting growth or fresh growth of superficial body growth including nails, hair or hairs.