Abstract: A system includes a tubing set and a drive assembly. The tubing set includes inlet tubing couplable to a source of fluid, a valve coupled to the inlet tubing, a syringe coupled to the inlet tubing via the valve, and outlet tubing coupled to the valve. The valve is configured to allow fluid to be drawn from the source of fluid via the inlet tubing into a syringe body of the syringe and to be expelled from the syringe body and through the outlet tubing, and to prevent fluid from being drawn from the outlet tubing into the syringe body and to prevent fluid expelled from the syringe body from flowing through the inlet tubing. The drive assembly is configured to reversibly receive the tubing set such that a drive mechanism is engaged with a plunger of the syringe to reciprocally translate the plunger relative to the syringe body.

Abstract: In some embodiments, a housing can define a reservoir. A lower cap can be coupled to the housing and define an outlet, and an upper cap can be coupled to the housing and can define an inlet. The upper cap can include an extending portion extending laterally a distance beyond an outermost extending portion of the lower cap relative to a central axis of the housing such that, when the lower cap and the extending portion of the upper cap contact a horizontal surface, the central axis of the housing is transverse to the surface and a sealing member is configured to sealingly engage a sealing surface of a valve seat prior to a liquid fluid level within a reservoir decreasing below a minimum threshold fluid level.

Abstract: In some embodiments, a system can include a fluid delivery assembly and a drive assembly. The fluid delivery assembly is configured to be releasably mechanically and, optionally, electrically coupled to the drive assembly. When the fluid delivery assembly is releasably coupled to the drive assembly, the drive assembly can control delivery of fluid from the fluid delivery assembly (e.g., to a patient). For example, the drive assembly can be releasably coupled to the fluid delivery assembly to control delivery of fluid from the fluid delivery assembly to provide continuous (e.g., non-pulsatile) fluid flow from the fluid delivery assembly.

Abstract: A system includes a tubing set and a drive assembly. The tubing set includes inlet tubing couplable to a source of fluid, a valve coupled to the inlet tubing, a syringe coupled to the inlet tubing via the valve, and outlet tubing coupled to the valve. The valve is configured to allow fluid to be drawn from the source of fluid via the inlet tubing into a syringe body of the syringe and to be expelled from the syringe body and through the outlet tubing, and to prevent fluid from being drawn from the outlet tubing into the syringe body and to prevent fluid expelled from the syringe body from flowing through the inlet tubing. The drive assembly is configured to reversibly receive the tubing set such that a drive mechanism is engaged with a plunger of the syringe to reciprocally translate the plunger relative to the syringe body.

Abstract: In some embodiments, a housing can define a reservoir. A lower cap can be coupled to the housing and define an outlet, and an upper cap can be coupled to the housing and can define an inlet. The upper cap can include an extending portion extending laterally a distance beyond an outermost extending portion of the lower cap relative to a central axis of the housing such that, when the lower cap and the extending portion of the upper cap contact a horizontal surface, the central axis of the housing is transverse to the surface and a sealing member is configured to sealingly engage a sealing surface of a valve seat prior to a liquid fluid level within a reservoir decreasing below a minimum threshold fluid level.

Abstract: In some embodiments, a system can include a fluid delivery assembly and a drive assembly. The fluid delivery assembly is configured to be releasably mechanically and, optionally, electrically coupled to the drive assembly. When the fluid delivery assembly is releasably coupled to the drive assembly, the drive assembly can control delivery of fluid from the fluid delivery assembly (e.g., to a patient). For example, the drive assembly can be releasably coupled to the fluid delivery assembly to control delivery of fluid from the fluid delivery assembly to provide continuous (e.g., non-pulsatile) fluid flow from the fluid delivery assembly.

Abstract: An infusion device includes a housing with an interior chamber sized and configured to hold at least a flange and plunger of a syringe, a trigger held by the housing, and a lever in communication with the trigger and including an upwardly extending cam with a cam path having an upper end. The cam is in communication with the flange of the syringe. In response to actuation of the trigger to dispense fluid from the syringe, the upper end of the cam travels upward above the syringe and longitudinally toward a dispensing end of the syringe to linearly translate the plunger of the syringe in a first direction to dispense fluid from the syringe. To refill fluid into the syringe, the upper end of the cam travels downward and longitudinally away from the dispensing end of the syringe to linearly translate the plunger in a second direction to intake fluid.

Abstract: In some embodiments, a tube portion can be configured to be fluidically coupled to a patient access component. A source of pressurized fluid can be coupled to the tube portion and can be configured to deliver fluid to the tube portion at a source pressure. A fluid pressure regulating device can include an expandable reservoir and can be coupled to the tube portion such that the expandable reservoir is in fluidic communication with the tube portion. The fluid pressure regulating device can be configured such that, when fluid is delivered from the source of pressurized fluid to the lumen of the tube portion at the source pressure, the expandable reservoir of the fluid pressure regulating device can receive fluid such that the expandable reservoir of the fluid pressure regulating device expands and fluid is delivered from the lumen of the tube portion to the patient via the patient access component.

Abstract: In some embodiments, a housing can define a reservoir. A lower cap can be coupled to the housing and define an outlet, and an upper cap can be coupled to the housing and can define an inlet. The upper cap can include an extending portion extending laterally a distance beyond an outermost extending portion of the lower cap relative to a central axis of the housing such that, when the lower cap and the extending portion of the upper cap contact a horizontal surface, the central axis of the housing is transverse to the surface and a sealing member is configured to sealingly engage a sealing surface of a valve seat prior to a liquid fluid level within a reservoir decreasing below a minimum threshold fluid level.

Abstract: In some embodiments, a housing can define a reservoir. A lower cap can be coupled to the housing and define an outlet, and an upper cap can be coupled to the housing and can define an inlet. The upper cap can include an extending portion extending laterally a distance beyond an outermost extending portion of the lower cap relative to a central axis of the housing such that, when the lower cap and the extending portion of the upper cap contact a horizontal surface, the central axis of the housing is transverse to the surface and a sealing member is configured to sealingly engage a sealing surface of a valve seat prior to a liquid fluid level within a reservoir decreasing below a minimum threshold fluid level.

Abstract: An infusion device includes a housing with an interior chamber sized and configured to hold at least a flange and plunger of a syringe, a trigger held by the housing, and a lever in communication with the trigger and including an upwardly extending cam with a cam path having an upper end. The cam is in communication with the flange of the syringe. In response to actuation of the trigger to dispense fluid from the syringe, the upper end of the cam travels upward above the syringe and longitudinally toward a dispensing end of the syringe to linearly translate the plunger of the syringe in a first direction to dispense fluid from the syringe. To refill fluid into the syringe, the upper end of the cam travels downward and longitudinally away from the dispensing end of the syringe to linearly translate the plunger in a second direction to intake fluid.

Abstract: An infusion device includes a housing with an interior chamber sized and configured to hold at least a flange and plunger of a syringe, a trigger held by the housing, and a lever in communication with the trigger and including an upwardly extending cam with a cam path having an upper end. The cam is in communication with the flange of the syringe. In response to actuation of the trigger to dispense fluid from the syringe, the upper end of the cam travels upward above the syringe and longitudinally toward a dispensing end of the syringe to linearly translate the plunger of the syringe in a first direction to dispense fluid from the syringe. To refill fluid into the syringe, the upper end of the cam travels downward and longitudinally away from the dispensing end of the syringe to linearly translate the plunger in a second direction to intake fluid.

Abstract: A kit of components for a medical infusion includes a syringe having a syringe body with a liquid chamber having a volumetric capacity in a range of 5 ml to 30 ml, large bore tubing having an inner diameter greater than 3 mm and less than or equal to 6 mm and a length in a range of 4 feet to 10 feet, a valve with an axially extending valve body with opposing first and second ends, and a package holding the syringe pre-attached to the valve body and the large bore tubing in a sterile condition to thereby provide components in a ready-to-use configuration for insertion of the syringe and valve into an infusion device. The valve body includes an inlet tube residing between the first and second ends of the valve body and an exit port on the first end of the valve body.

Abstract: An infusion device includes a housing with an interior chamber sized and configured to hold at least a flange and plunger of a syringe, a trigger held by the housing, and a lever in communication with the trigger and including an upwardly extending cam with a cam path having an upper end. The cam is in communication with the flange of the syringe. In response to actuation of the trigger to dispense fluid from the syringe, the upper end of the cam travels upward above the syringe and longitudinally toward a dispensing end of the syringe to linearly translate the plunger of the syringe in a first direction to dispense fluid from the syringe. To refill fluid into the syringe, the upper end of the cam travels downward and longitudinally away from the dispensing end of the syringe to linearly translate the plunger in a second direction to intake fluid.