Patents Assigned to A. Menarini Industrie Farmaceutiche Riunite S.r.l.
  • Patent number: 8309362
    Abstract: A process is described for the preparation of modified electrodes useful for the measurement of analytes in biological fluids, comprising the deposition of Prussian blue on screen printed electrodes, and the modified electrodes prepared via said process; the enzymatic electrodes and the biosensors comprising said modified electrodes and the method for the determination of analytes in biological fluids which uses said modified electrodes are also described.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: November 13, 2012
    Assignee: A. Menarini Industrie Farmaceutiche Riunite S.R.L.
    Inventors: Giuseppe Palleschi, Francesco Ricci, Danila Moscone, Alessandro Poscia
  • Patent number: 8273228
    Abstract: Portable device for the measurement and control of analytes in biological fluids, provided with biosensor for measurement and control of biological fluids such as glucose and other analytes characterized by the possibility of using electrolytic cells with two, three or more electrodes, with polarization voltage between a few millivolts and 100 millivolts; the possibility of measuring the fluid temperature at the outlet of the electrolytic cell in high resolution mode for diagnostic purposes, hence it can also be used for performing very accurate thermal compensation of the electrochemical measurement; the possibility of performing optimised correction of both the systematic and random errors in the measurement performed; the possibility of calibrating the sensors used more accurately and efficiently and, lastly, the possibility of performing the measurement with much lower polarization voltages at the electrodes than the equipment in the state of the art with consequent benefits in terms of reduced wear of th
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: September 25, 2012
    Assignee: A. Menarini Industrie Farmaceutiche Riunite S.R.L.
    Inventors: Giorgio Dall'Oglio, Francesco Valgimigli
  • Patent number: 7989008
    Abstract: The invention relates to a new derivative of aryldimethylpyrazolone of formula (I) which is effective in reducing unsightly cellulite, and compositions containing it.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: August 2, 2011
    Assignee: Menarini Industrie Farmaceutiche Riunite S.R.L.
    Inventor: Alberto Aleotti
  • Publication number: 20100112104
    Abstract: The invention relates to a new derivative of aryldimethylpyrazolone of formula (I) which is effective in reducing unsightly cellulite, and compositions containing it.
    Type: Application
    Filed: March 20, 2008
    Publication date: May 6, 2010
    Applicant: A.MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L.
    Inventor: Alberto Aleotti
  • Patent number: 6618603
    Abstract: An apparatus for the continuous measurement of glucose and lactate in interstitial fluids including a glucose measurement cell, an A/D conversion block, a memory block and a bi-directional communication between the interface block and an external calculation unit.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: September 9, 2003
    Assignee: Menarini Industrie Farmaceutiche Riunite S.r.L.
    Inventors: Maurizio Claudio Varalli, Alessandro Poscia
  • Patent number: 6153747
    Abstract: Process for the preparation of 2-halomethyl-penems (I) comprising (a) reacting an acetoxy-(protected hydroxyethyl)-2-azetidinone (III) with a 2-halothioacetic acid to form a 3-haloacetylthioazetidinone (V), (b) reacting (V) with oxalyl chloride to give an intermediate (VII), acylated on the beta-lactamic nitrogen, and (c) cyclizing (VII) in the presence of an organic phosphate or phosphonite to produce the corresponding 2-halomethyl-penem (I).
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: November 28, 2000
    Assignees: A. Menarini Industrie Farmaceutiche Riunite S.r.l., Istituto Luso Farmaco D'Italia S.p.A.
    Inventors: Enzo Perrotta, Maria Altamura
  • Patent number: 6150325
    Abstract: This invention relates to novel compounds of general formula (I): ##STR1## and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: November 21, 2000
    Assignee: A. Menarini Industrie Farmaceutiche Riunite S.r.l.
    Inventors: Federico Arcamone, Carlo Alberto Maggi, Laura Quartara, Danilo Giannotti
  • Patent number: 5849795
    Abstract: The present invention refers to tachykinins antagonists of general formula (I) ##STR1## their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: December 15, 1998
    Assignee: A Menarini Industrie Farmaceutiche Riunite S.r.l.
    Inventors: Alessandro Sisto, Edoardo Potier, Stefano Manzini, Christopher Fincham, Paolo Lombardi, Federico Arcamone
  • Patent number: 5814608
    Abstract: 8-fluoro-anthracyclines of formula (I) have anti-tumor activity. ##STR1## wherein: R is chosen in the group consisting of H, OH, OR.sub.4 wherein R.sub.4 is chosen in the group consisting of CHO, COCH.sub.3, acyl derivative of a carboxylic acid containing up to 6 carbon atoms;R.sub.1 is chosen in the group consisting of: H, OH, OCH.sub.3 ;R.sub.2 is chosen in the group consisting of: H, OH, NH.sub.2R.sub.3 is chosen in the group consisting of: H, OH, NH.sub.2, residue of formula (A) ##STR2## The compounds are characterized by having cis-stereochemistry between the groups 8--F and 9--OH. Their preparation and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: April 21, 1997
    Date of Patent: September 29, 1998
    Assignees: Bristol-Myers Squibb, S.p.A., A. Menarini Industrie Farmaceutiche Riunite S.R.L.
    Inventors: Fabio Animati, Federico Arcamone, Giuseppe Giannini, Paolo Lombardi, Edith Monteagudo
  • Patent number: 5807835
    Abstract: New 8-fluoroanthracycline derivatives of formula I possessing antitumoral properties are described, together with their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: May 14, 1991
    Date of Patent: September 15, 1998
    Assignee: A. Menarini Industrie Farmaceutiche Riunite S.r.l.
    Inventors: Fabio Animati, Paolo Lombardi, Federico Arcamone
  • Patent number: 5801152
    Abstract: The present invention is referred to compounds of general formula (I) and (II), respectively ##STR1## their pharmaceutically acceptable salts, the process for their preparation, and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 28, 1996
    Date of Patent: September 1, 1998
    Assignees: A. Menarini Industrie Farmaceutiche Riunite S.r.l., Bristol-Myers Squibb S.p.A.
    Inventors: Fabio Animati, Paolo Lombardi, Frederico Arcamone, Amalia Cipollone
  • Patent number: 5760248
    Abstract: A description is given of tachykinin receptor antagonists having general formula (I) ##STR1## their preparation and use in pharmaceutical formulations.
    Type: Grant
    Filed: May 31, 1996
    Date of Patent: June 2, 1998
    Assignee: A.Menarini Industrie Farmaceutiche Riunite S.r.l.
    Inventors: Alessandro Sisto, Christopher Fincham, Edoardo Potier, Stefano Manzini, Federico Arcamone, Paolo Lombardi
  • Patent number: 5698710
    Abstract: The present invention refers to tachykinins antagonists of general formula (I) ##STR1## their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 8, 1996
    Date of Patent: December 16, 1997
    Assignee: A. Menarini Industrie Farmaceutiche Riunite S.r.l.
    Inventors: Alessandro Sisto, Edoardo Potier, Stefano Manzini, Christopher Fincham, Paolo Lombardi, Federico Arcamone
  • Patent number: 5472976
    Abstract: This invention relates to polyaminopyrrolecarboxyamide derivatives of general formula (I) and their pharmaceutically acceptable salts, in which A represents a chemical bond or an aromatic or heteroaromatic radical, and:if A is a chemical bond, R is hydrogen, alkyl, dialkylaminoalkyl, alkenyl, cycloalkyl, arylalkyl, arylalkenyl, haloalkyl, or an aromatic or heteroaromatic radical;whereas if A is an aromatic or heteroaromatic radical, R is nitro, amino or formylamino;n is 0 or a whole number between 1 and 4;Z is an alkylene or aromatic radical.
    Type: Grant
    Filed: August 6, 1993
    Date of Patent: December 5, 1995
    Assignees: A. Menarini Industrie Farmaceutiche Riunite S.r.l., Bristol-Meyers Squibb S.p.A.
    Inventors: Fabio Animati, Federico Arcamone, Giuseppe Giannini, Paolo Lombardi
  • Patent number: 5128447
    Abstract: A synthetic peptide corresponding to the following formula:X--Asp--Y--DTrp--Val--DTrp--Z--K--NH.sub.2where:X=H, Arg, DArg, Lys, DLys, Thr, DThrY=Tyr, Trp, DTrp, Ser, MetZ=Trp, DTrpK=Arg, Phe, DTrp, Tyr, Metand pharmaceutically acceptable salts thereof with organic and inorganic acids as competitive antagonists against neurokinin A (NK-2 receptor).
    Type: Grant
    Filed: May 24, 1990
    Date of Patent: July 7, 1992
    Assignee: A. Menarini Industrie Farmaceutiche Riunite S.r.l.
    Inventors: Paolo Rovero, Vittorio Pestellini, Carlo A. Maggi, Riccardo Patacchini, Paolo Santicioli, Sandro Giuliani, Alberto Meli